STRINGSTRING
AFM17918.1 AFM17918.1 murI murI murA murA AFM18505.1 AFM18505.1 AFM18692.1 AFM18692.1 AFM18708.1 AFM18708.1 glmU glmU AFM18929.1 AFM18929.1 AFM19164.1 AFM19164.1 AFM19245.1 AFM19245.1 AFM19350.1 AFM19350.1 AFM19431.1 AFM19431.1 AFM19548.1 AFM19548.1 AFM19549.1 AFM19549.1 AFM14990.1 AFM14990.1 AFM19659.1 AFM19659.1 AFM19665.1 AFM19665.1 AFM19666.1 AFM19666.1 AFM19667.1 AFM19667.1 AFM19668.1 AFM19668.1 AFM19597.1 AFM19597.1 AFM14974.1 AFM14974.1 AFM14851.1 AFM14851.1 AFM14850.1 AFM14850.1 AFM19669.1 AFM19669.1 AFM19670.1 AFM19670.1 AFM19671.1 AFM19671.1 AFM19681.1 AFM19681.1 AFM19682.1 AFM19682.1 AFM19684.1 AFM19684.1 AFM19685.1 AFM19685.1 AFM19703.1 AFM19703.1 AFM20009.1 AFM20009.1 AFM15002.1 AFM15002.1 AFM15011.1 AFM15011.1 AFM15049.1 AFM15049.1 AFM15066.1 AFM15066.1 uppP uppP AFM15373.1 AFM15373.1 murB murB AFM15583.1 AFM15583.1 AFM15669.1 AFM15669.1 AFM15973.1 AFM15973.1 AFM15986.1 AFM15986.1 AFM16135.1 AFM16135.1 AFM16167.1 AFM16167.1 AFM16206.1 AFM16206.1 AFM16255.1 AFM16255.1 AFM16602.1 AFM16602.1 ddl ddl AFM16694.1 AFM16694.1 AFM16695.1 AFM16695.1 AFM16699.1 AFM16699.1 AFM16702.1 AFM16702.1 AFM16736.1 AFM16736.1 AFM16799.1 AFM16799.1 AFM16967.1 AFM16967.1 mltG mltG AFM17222.1 AFM17222.1 AFM17239.1 AFM17239.1 AFM17698.1 AFM17698.1 uppP-2 uppP-2 murC murC murG murG murD murD mraY mraY murF murF murE murE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFM17918.1Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. (639 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (277 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (412 aa)
AFM18505.1UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; PFAM: Glycosyl transferase family 4. (403 aa)
AFM18692.1Putative regulator of cell autolysis; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (408 aa)
AFM18708.1Putative RND superfamily drug exporter; PFAM: MMPL family. (764 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase, UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (489 aa)
AFM18929.1PFAM: Probable lipoprotein LpqN. (235 aa)
AFM19164.1Transcriptional attenuator, LytR family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. (668 aa)
AFM19245.1D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (232 aa)
AFM19350.1Hypothetical protein. (823 aa)
AFM19431.1D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family. (457 aa)
AFM19548.1UDP-N-acetylmuramyl tripeptide synthase; PFAM: Domain of unknown function (DUF1727); Mur ligase middle domain. (408 aa)
AFM19549.1PFAM: CobB/CobQ-like glutamine amidotransferase domain. (238 aa)
AFM14990.1Hypothetical protein; PFAM: L,D-transpeptidase catalytic domain. (339 aa)
AFM19659.1Putative glycosyltransferase; PFAM: Glycosyl transferase family 2. (336 aa)
AFM19665.1Putative membrane protein; PFAM: GtrA-like protein. (132 aa)
AFM19666.1FAD/FMN-dependent dehydrogenase; PFAM: D-arabinono-1,4-lactone oxidase; FAD binding domain. (462 aa)
AFM19667.1Short-chain dehydrogenase of unknown substrate specificity; PFAM: short chain dehydrogenase. (260 aa)
AFM19668.1PFAM: Arabinofuranosyltransferase N terminal; Arabinofuranosyltransferase A C terminal. (657 aa)
AFM19597.1Putative RND superfamily drug exporter; PFAM: MMPL family. (738 aa)
AFM14974.1ATP-grasp enzyme, D-alanine-D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus. (348 aa)
AFM14851.1Bacterial cell division membrane protein; PFAM: Cell cycle protein; Belongs to the SEDS family. (471 aa)
AFM14850.1Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain. (491 aa)
AFM19669.1PFAM: Mycobacterial cell wall arabinan synthesis protein. (1080 aa)
AFM19670.1PFAM: Mycobacterial cell wall arabinan synthesis protein. (1084 aa)
AFM19671.1PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase; PFAM: Mycobacterial cell wall arabinan synthesis protein. (1080 aa)
AFM19681.1Hypothetical protein. (660 aa)
AFM19682.14-hydroxybenzoate polyprenyltransferase-like prenyltransferase; PFAM: UbiA prenyltransferase family; Belongs to the UbiA prenyltransferase family. (327 aa)
AFM19684.1Putative glycosyltransferase; PFAM: Glycosyl transferase family 2. (647 aa)
AFM19685.1PFAM: UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase. (407 aa)
AFM19703.1Transcriptional attenuator, LytR family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. (310 aa)
AFM20009.1Putative RNA-binding protein; PFAM: R3H domain. (189 aa)
AFM15002.1Putative RND superfamily drug exporter; PFAM: MMPL family. (974 aa)
AFM15011.1Putative RND superfamily drug exporter; PFAM: MMPL family. (1011 aa)
AFM15049.1PFAM: F5/8 type C domain; Domain of unknown function (DUF3367). (1399 aa)
AFM15066.1PFAM: Protein of unknown function (DUF2910); manually curated. (224 aa)
uppPPutative bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (301 aa)
AFM15373.1PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain; manually curated. (545 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (341 aa)
AFM15583.1Putative RND superfamily drug exporter; PFAM: MMPL family. (730 aa)
AFM15669.1Putative RND superfamily drug exporter; PFAM: MMPL family; manually curated; non-canonical start codon. (746 aa)
AFM15973.1PFAM: D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (400 aa)
AFM15986.1Putative RND superfamily drug exporter; PFAM: MMPL family. (739 aa)
AFM16135.1Transcriptional attenuator, LytR family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. (490 aa)
AFM16167.1Putative phosphohydrolase. (310 aa)
AFM16206.1Hypothetical protein. (404 aa)
AFM16255.1Hypothetical protein; PFAM: L,D-transpeptidase catalytic domain. (303 aa)
AFM16602.1WD40-like repeat protein. (426 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (367 aa)
AFM16694.1PFAM: D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (278 aa)
AFM16695.1PFAM: D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (297 aa)
AFM16699.1Putative RNA-binding protein (contains KH domain); Belongs to the UPF0109 family. (80 aa)
AFM16702.1Beta-lactamase class A. (313 aa)
AFM16736.1Hypothetical protein. (255 aa)
AFM16799.1GNAT-family acetyltransferase TIGR03103; PFAM: RimK-like ATP-grasp domain; Acetyltransferase (GNAT) family; TIGRFAM: GNAT-family acetyltransferase TIGR03103. (594 aa)
AFM16967.1PFAM: Protein of unknown function (DUF2029); manually curated. (427 aa)
mltGPutative periplasmic solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (415 aa)
AFM17222.1Hypothetical protein. (573 aa)
AFM17239.1Cell wall-associated hydrolase, invasion-associated protein; PFAM: NlpC/P60 family. (484 aa)
AFM17698.1PFAM: Beta-lactamase. (308 aa)
uppP-2Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (276 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (487 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (379 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (484 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (359 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (507 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (492 aa)
Your Current Organism:
Mycolicibacterium chubuense
NCBI taxonomy Id: 710421
Other names: M. chubuense NBB4, Mycobacterium chubuense NBB4, Mycolicibacterium chubuense NBB4
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