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cbiN cbiN cbiA cbiA cbiC cbiC cbiD cbiD ALA94790.1 ALA94790.1 ALA94791.1 ALA94791.1 ALA94793.1 ALA94793.1 ALA94794.1 ALA94794.1 cbiF cbiF ALA94797.1 ALA94797.1 ALA94798.1 ALA94798.1 ALA96550.1 ALA96550.1 ALA96553.1 ALA96553.1 ALA94815.1 ALA94815.1 ribH ribH pckA pckA ALA94676.1 ALA94676.1 ALA94686.1 ALA94686.1 ALA94742.1 ALA94742.1 metE metE ALA94818.1 ALA94818.1 ALA94757.1 ALA94757.1 cobQ cobQ cobD cobD ALA96546.1 ALA96546.1 ALA94777.1 ALA94777.1 cobS cobS ALA94782.1 ALA94782.1 cbiM cbiM ALA96475.1 ALA96475.1 ALA96466.1 ALA96466.1 ALA96448.1 ALA96448.1 ALA96444.1 ALA96444.1 pgi pgi ALA96413.1 ALA96413.1 pgk pgk ALA96398.1 ALA96398.1 ALA96397.1 ALA96397.1 ALA96383.1 ALA96383.1 acpS acpS folD folD ALA96265.1 ALA96265.1 apt apt tgt tgt ALA96247.1 ALA96247.1 ALA96730.1 ALA96730.1 ALA96242.1 ALA96242.1 ALA96207.1 ALA96207.1 ALA96180.1 ALA96180.1 ALA96165.1 ALA96165.1 ALA96721.1 ALA96721.1 ALA96148.1 ALA96148.1 queA queA proB proB proA proA proC proC ALA96071.1 ALA96071.1 ALA96030.1 ALA96030.1 ALA96711.1 ALA96711.1 aroB aroB aroA aroA aroC aroC ALA96702.1 ALA96702.1 ilvD ilvD ALA95981.1 ALA95981.1 ALA95980.1 ALA95980.1 ALA95979.1 ALA95979.1 ALA95966.1 ALA95966.1 leuC leuC leuD leuD leuB leuB ilvC ilvC ALA95945.1 ALA95945.1 accD accD accA accA asnA asnA glyA glyA ALA95919.1 ALA95919.1 lysA lysA ALA95913.1 ALA95913.1 dapF dapF asd asd ALA96695.1 ALA96695.1 aroE aroE aroK aroK aroQ aroQ ALA96691.1 ALA96691.1 ALA96683.1 ALA96683.1 ALA95827.1 ALA95827.1 metAA metAA ALA95779.1 ALA95779.1 serS serS ALA96670.1 ALA96670.1 ALA96668.1 ALA96668.1 ALA95742.1 ALA95742.1 ALA95741.1 ALA95741.1 fbp fbp purC purC ALA95713.1 ALA95713.1 ALA96658.1 ALA96658.1 fabZ fabZ ALA95660.1 ALA95660.1 ALA95640.1 ALA95640.1 ALA95631.1 ALA95631.1 ALA95616.1 ALA95616.1 ALA95615.1 ALA95615.1 ALA96648.1 ALA96648.1 ALA95549.1 ALA95549.1 acpP acpP ALA95547.1 ALA95547.1 fabH fabH ALA95533.1 ALA95533.1 ALA95480.1 ALA95480.1 thrB thrB ALA95463.1 ALA95463.1 ALA95452.1 ALA95452.1 ALA95426.1 ALA95426.1 ALA95425.1 ALA95425.1 ALA95424.1 ALA95424.1 ALA96631.1 ALA96631.1 ALA95399.1 ALA95399.1 ALA95372.1 ALA95372.1 ALA95371.1 ALA95371.1 fabV fabV ALA95363.1 ALA95363.1 dapB dapB ALA95356.1 ALA95356.1 kdsA kdsA ALA95270.1 ALA95270.1 ALA96616.1 ALA96616.1 thiI thiI ALA95146.1 ALA95146.1 ALA95091.1 ALA95091.1 tpiA tpiA ALA95012.1 ALA95012.1 ALA95006.1 ALA95006.1 ALA94975.1 ALA94975.1 ALA94957.1 ALA94957.1 ALA94938.1 ALA94938.1 pdxS pdxS pdxT pdxT ALA96568.1 ALA96568.1 trpD trpD ALA94918.1 ALA94918.1 trpF trpF trpB trpB trpA trpA xpt xpt ALA94875.1 ALA94875.1 ribBA ribBA ALA94819.1 ALA94819.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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cbiNCobalt transporter; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (100 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (447 aa)
cbiCCatalyzes the interconversion of precorrin-8X and cobyrinic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (374 aa)
ALA94790.1precorrin-6Y C5,15-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
ALA94791.1precorrin-8W decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
ALA94793.1Precorrin-2 C20-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (238 aa)
ALA94794.1Pyridoxamine 5-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
cbiFCatalyzes the formation of cobalt-precorrin-5 from cobalt-precorrin-4; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
ALA94797.1Cobalamin biosynthesis protein CbiG; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ALA94798.1cobalt-precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (246 aa)
ALA96550.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
ALA96553.1Cobalamin biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
ALA94815.1Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (154 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (527 aa)
ALA94676.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
ALA94686.1Prenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
ALA94742.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (762 aa)
ALA94818.15-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (382 aa)
ALA94757.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (512 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (317 aa)
ALA96546.1Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (336 aa)
ALA94777.1Precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (242 aa)
ALA94782.1Cobalt chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
cbiMCobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (235 aa)
ALA96475.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
ALA96466.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
ALA96448.1Carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
ALA96444.1Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (175 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (451 aa)
ALA96413.1[FeFe] hydrogenase H-cluster radical SAM maturase HydG; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (408 aa)
ALA96398.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
ALA96397.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
ALA96383.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (122 aa)
folD5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (282 aa)
ALA96265.1acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (384 aa)
ALA96247.1Carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
ALA96730.1Glycine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
ALA96242.1Glycine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
ALA96207.1Selenophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
ALA96180.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
ALA96165.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
ALA96721.1methylcobamide:CoM methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
ALA96148.1Biotin attachment protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
queAS-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (340 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (381 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa)
ALA96071.11-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (587 aa)
ALA96030.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
ALA96711.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (363 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (431 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (368 aa)
ALA96702.1[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (554 aa)
ALA95981.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
ALA95980.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
ALA95979.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
ALA95966.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (191 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (352 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (336 aa)
ALA95945.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa)
accDacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)
accAacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
asnAAsparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa)
ALA95919.1Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (435 aa)
ALA95913.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (400 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (283 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (332 aa)
ALA96695.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (271 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
ALA96691.1Catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (156 aa)
ALA96683.1CDP-glycerol:glycerophosphate glycerophosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
ALA95827.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (160 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (307 aa)
ALA95779.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (250 aa)
serSHypothetical protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (423 aa)
ALA96670.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (173 aa)
ALA96668.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
ALA95742.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ALA95741.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (406 aa)
fbpClass 3; catalyzes the formation of fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (645 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
ALA95713.1Acetylornithine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
ALA96658.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1142 aa)
fabZ3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (141 aa)
ALA95660.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
ALA95640.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (330 aa)
ALA95631.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
ALA95616.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
ALA95615.1Carbamoylphosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ALA96648.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (315 aa)
ALA95549.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (411 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (74 aa)
ALA95547.1Malonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)
ALA95533.1Hypothetical protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (199 aa)
ALA95480.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (302 aa)
ALA95463.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (423 aa)
ALA95452.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
ALA95426.1Ornithine carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (401 aa)
ALA95425.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
ALA95424.1Diaminopropionate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
ALA96631.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
ALA95399.1Cobalamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (188 aa)
ALA95372.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)
ALA95371.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (397 aa)
ALA95363.12,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (231 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (242 aa)
ALA95356.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (278 aa)
ALA95270.1Phosphorylase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (225 aa)
ALA96616.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (395 aa)
ALA95146.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
ALA95091.1Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (429 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa)
ALA95012.1Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
ALA95006.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
ALA94975.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
ALA94957.1UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (235 aa)
ALA94938.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (289 aa)
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa)
ALA96568.1Histidinol phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PHP hydrolase family. HisK subfamily. (285 aa)
trpDAnthranilate synthase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (547 aa)
ALA94918.1Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (242 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (221 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (405 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (253 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (189 aa)
ALA94875.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (403 aa)
ALA94819.1Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
Your Current Organism:
Leptotrichia
NCBI taxonomy Id: 712357
Other names: L. sp. oral taxon 212, Leptotrichia sp. oral taxon 212
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