STRINGSTRING
mdh mdh AME02774.1 AME02774.1 pckA pckA AME03389.1 AME03389.1 AME03445.1 AME03445.1 AME03446.1 AME03446.1 AME03447.1 AME03447.1 AME03448.1 AME03448.1 AME03451.1 AME03451.1 AME03580.1 AME03580.1 sucD sucD sucC sucC AME03899.1 AME03899.1 AME03900.1 AME03900.1 AME03901.1 AME03901.1 AME03922.1 AME03922.1 AME03923.1 AME03923.1 AME03924.1 AME03924.1 AME03977.1 AME03977.1 AME03978.1 AME03978.1 AME03979.1 AME03979.1 AME03980.1 AME03980.1 AME03981.1 AME03981.1 AME04130.1 AME04130.1 AME04131.1 AME04131.1 fumC fumC AME04287.1 AME04287.1 AME04288.1 AME04288.1 AME04289.1 AME04289.1 sdhA sdhA sdhB sdhB AME04362.1 AME04362.1 AME04588.1 AME04588.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa)
AME02774.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (539 aa)
AME03389.1glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (375 aa)
AME03445.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
AME03446.12-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AME03447.12-oxoglutarate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AME03448.12-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AME03451.1L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (319 aa)
AME03580.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
AME03899.1Heterodisulfide reductase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
AME03900.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (318 aa)
AME03901.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
AME03922.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (727 aa)
AME03923.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
AME03924.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AME03977.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
AME03978.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
AME03979.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AME03980.1GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AME03981.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
AME04130.1Involved in the tartrate degradation pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AME04131.1Fumarate hydrolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
fumCClass II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (454 aa)
AME04287.1Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AME04288.1Fumarate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AME04289.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
AME04362.1Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1175 aa)
AME04588.1Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 713030
Other names: S. sp. oral taxon 136, Selenomonas sp. oral taxon 136
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