(29 nodes) Phosphotransferase system (PTS), and Zinc-binding dehydrogenase network (Selenomonas)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AXE86_01795	Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
	AME03081.1	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
	AME03082.1	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
	AME03228.1	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
	AME03232.1	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
	AME03233.1	PTS mannose/fructose/sorbose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
	AME03234.1	PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
	AME03235.1	RpiR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
	AXE86_03550	protein-N(pi)-phosphohistidine--sugar phosphotransferase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
	AME03237.1	Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
	AME03238.1	Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
	AME03631.1	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
	AME03632.1	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
	AME03684.1	Beta-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 26 family. (453 aa)
	AME03795.1	Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)
	AME03796.1	Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
	AME03816.1	PTS mannose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
	AME03817.1	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
	AME04754.1	PTS mannose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
	AME03818.1	PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
	AME03846.1	Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
	AME03898.1	DeoR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
	AME03929.1	PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (633 aa)
	AME03930.1	1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (302 aa)
	AME04207.1	Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
	AME04210.1	PTS sugar transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
	AME04274.1	protein-N(pi)-phosphohistidine--sugar phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
	AME04275.1	Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (483 aa)
	AME04629.1	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)

Your Current Organism:

Selenomonas

NCBI taxonomy Id: 713030
Other names: S. sp. oral taxon 136, Selenomonas sp. oral taxon 136

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AME03081.1	AME03082.1	AXE86_02700	AXE86_02705	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
AME03081.1	AME03238.1	AXE86_02700	AXE86_03560	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
AME03081.1	AME03631.1	AXE86_02700	AXE86_05845	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AME03081.1	AME03632.1	AXE86_02700	AXE86_05850	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AME03081.1	AME03929.1	AXE86_02700	AXE86_07510	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
AME03081.1	AME04207.1	AXE86_02700	AXE86_09025	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
AME03081.1	AME04274.1	AXE86_02700	AXE86_09405	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	protein-N(pi)-phosphohistidine--sugar phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.466
AME03082.1	AME03081.1	AXE86_02705	AXE86_02700	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
AME03082.1	AME03238.1	AXE86_02705	AXE86_03560	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
AME03082.1	AME03631.1	AXE86_02705	AXE86_05845	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AME03082.1	AME03632.1	AXE86_02705	AXE86_05850	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AME03082.1	AME03929.1	AXE86_02705	AXE86_07510	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
AME03082.1	AME04207.1	AXE86_02705	AXE86_09025	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
AME03082.1	AME04274.1	AXE86_02705	AXE86_09405	Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	protein-N(pi)-phosphohistidine--sugar phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.466
AME03228.1	AME03232.1	AXE86_03495	AXE86_03525	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AME03228.1	AME03233.1	AXE86_03495	AXE86_03530	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS mannose/fructose/sorbose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AME03228.1	AME03234.1	AXE86_03495	AXE86_03535	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AME03228.1	AME03238.1	AXE86_03495	AXE86_03560	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AME03228.1	AME03631.1	AXE86_03495	AXE86_05845	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.446
AME03228.1	AME03632.1	AXE86_03495	AXE86_05850	PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.	PTS fructose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.446