STRINGSTRING
AME02616.1 AME02616.1 ispF ispF ispD ispD AME02873.1 AME02873.1 AME02874.1 AME02874.1 AME02901.1 AME02901.1 AME03053.1 AME03053.1 AME03144.1 AME03144.1 AME03190.1 AME03190.1 AME03191.1 AME03191.1 kdsA kdsA kdsB kdsB lpxK lpxK AME03197.1 AME03197.1 lpxA lpxA fabZ fabZ lpxC lpxC AME03290.1 AME03290.1 AME03436.1 AME03436.1 AME03437.1 AME03437.1 AME04746.1 AME04746.1 AME03764.1 AME03764.1 AME03797.1 AME03797.1 AME03815.1 AME03815.1 AME04759.1 AME04759.1 AME04035.1 AME04035.1 lpxD lpxD AME04041.1 AME04041.1 acpS acpS AME04177.1 AME04177.1 plsX plsX fabH fabH AME04338.1 AME04338.1 acpP acpP AME04342.1 AME04342.1 AME04419.1 AME04419.1 AME04436.1 AME04436.1 ispH ispH ispE ispE glmU glmU AME04544.1 AME04544.1 plsY plsY ispG ispG AME04650.1 AME04650.1 AME04651.1 AME04651.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AME02616.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (158 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (256 aa)
AME02873.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (237 aa)
AME02874.1Phosphatidylserine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
AME02901.1Galactosyldiacylglycerol synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
AME03053.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AME03144.1Glycosyl transferase family 39; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
AME03190.1Lipid A biosynthesis acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AME03191.13-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (275 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (244 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (840 aa)
AME03197.1lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (381 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (270 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (300 aa)
AME03290.1SpoIVB peptidase S55 domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (690 aa)
AME03436.1Heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
AME03437.1Lipopolysaccharide heptosyltransferase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
AME04746.1Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
AME03764.11-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (586 aa)
AME03797.11-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (586 aa)
AME03815.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (449 aa)
AME04759.1Trans-hexaprenyltranstransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (321 aa)
AME04035.1Glycosyl transferase family 39; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (340 aa)
AME04041.1Lipid A biosynthesis acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
acpS4-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (124 aa)
AME04177.1Chain-length determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (338 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (334 aa)
AME04338.1Malonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (76 aa)
AME04342.1Beta-ketoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (416 aa)
AME04419.1Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (326 aa)
AME04436.1Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (291 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (276 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (291 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (454 aa)
AME04544.1Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (200 aa)
plsYAcyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (193 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (359 aa)
AME04650.1Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (273 aa)
AME04651.1UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (264 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 713030
Other names: S. sp. oral taxon 136, Selenomonas sp. oral taxon 136
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