STRINGSTRING
thiM-2 thiM-2 AME04304.1 AME04304.1 AME04382.1 AME04382.1 gmk gmk AME03131.1 AME03131.1 AME03129.1 AME03129.1 AME03119.1 AME03119.1 galK galK AME03078.1 AME03078.1 pfp pfp AME02955.1 AME02955.1 AME02925.1 AME02925.1 AME02916.1 AME02916.1 coaX coaX AME02858.1 AME02858.1 AME02849.1 AME02849.1 AME02755.1 AME02755.1 AME02616.1 AME02616.1 AME04385.1 AME04385.1 proB proB nadK nadK AME04458.1 AME04458.1 ispE ispE prs prs AME04491.1 AME04491.1 cmk cmk AME04565.1 AME04565.1 AME04578.1 AME04578.1 AME04607.1 AME04607.1 AME04629.1 AME04629.1 argB argB thrB thrB pyrH pyrH AME04661.1 AME04661.1 coaE coaE AME03183.1 AME03183.1 ndk ndk lpxK lpxK AME03214.1 AME03214.1 AME03228.1 AME03228.1 AME04712.1 AME04712.1 AME03234.1 AME03234.1 AME03238.1 AME03238.1 pfkA pfkA AME03357.1 AME03357.1 AME03435.1 AME03435.1 AME03438.1 AME03438.1 AME03439.1 AME03439.1 AME04730.1 AME04730.1 thiM thiM AME03488.1 AME03488.1 AME03517.1 AME03517.1 AME04732.1 AME04732.1 pfkA-2 pfkA-2 AME04737.1 AME04737.1 AME03616.1 AME03616.1 AME03621.1 AME03621.1 AME03625.1 AME03625.1 AME03708.1 AME03708.1 AME03726.1 AME03726.1 AME03765.1 AME03765.1 rbsK rbsK AME03790.1 AME03790.1 AME03795.1 AME03795.1 AME03816.1 AME03816.1 AME03817.1 AME03817.1 AME03841.1 AME03841.1 AME03843.1 AME03843.1 AME03915.1 AME03915.1 AME03924.1 AME03924.1 AME03930.1 AME03930.1 AME03937.1 AME03937.1 AME03980.1 AME03980.1 AME04080.1 AME04080.1 aroK aroK AME04165.1 AME04165.1 AME04167.1 AME04167.1 pgk pgk tpiA tpiA gpmI gpmI AME04207.1 AME04207.1 AME04214.1 AME04214.1 AME04216.1 AME04216.1 AME04234.1 AME04234.1 eno eno AME04274.1 AME04274.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thiM-2Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa)
AME04304.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AME04382.1Bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (197 aa)
AME03131.1Cholinephosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
AME03129.1Choline-phosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AME03119.1Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (389 aa)
AME03078.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa)
AME02955.17, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
AME02925.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
AME02916.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa)
AME02858.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa)
AME02849.1ATP--guanido phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
AME02755.1Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyridoxine kinase family. (277 aa)
AME02616.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AME04385.1GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (374 aa)
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (284 aa)
AME04458.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (291 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
AME04491.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (410 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AME04565.1Protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
AME04578.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
AME04607.1Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (319 aa)
AME04629.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (294 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (316 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
AME04661.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
AME03183.1LytTR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (840 aa)
AME03214.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (310 aa)
AME03228.1PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AME04712.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
AME03234.1PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
AME03238.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
pfkAATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)
AME03357.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
AME03435.1Heptose 1-phosphate adenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
AME03438.1Hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (154 aa)
AME03439.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
AME04730.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa)
AME03488.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
AME03517.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (731 aa)
AME04732.1Fructose transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
pfkA-2ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
AME04737.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
AME03616.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
AME03621.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
AME03625.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
AME03708.1With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
AME03726.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
AME03765.1Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
AME03790.1Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
AME03795.1Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)
AME03816.1PTS mannose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
AME03817.1PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
AME03841.1Gluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family. (516 aa)
AME03843.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
AME03915.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
AME03924.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AME03930.11-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (302 aa)
AME03937.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
AME03980.1GTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AME04080.1Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (682 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
AME04165.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
AME04167.1Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (405 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (518 aa)
AME04207.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AME04214.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
AME04216.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AME04234.1Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
AME04274.1protein-N(pi)-phosphohistidine--sugar phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 713030
Other names: S. sp. oral taxon 136, Selenomonas sp. oral taxon 136
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