STRINGSTRING
nanE nanE surE surE AME02630.1 AME02630.1 dtd dtd rnhB rnhB AME02657.1 AME02657.1 hslV hslV AME04684.1 AME04684.1 AME02769.1 AME02769.1 AXE86_01110 AXE86_01110 lon lon AME04692.1 AME04692.1 AME02856.1 AME02856.1 ftsH ftsH AME02904.1 AME02904.1 AME02980.1 AME02980.1 AME02984.1 AME02984.1 pfp pfp AME03011.1 AME03011.1 AME03014.1 AME03014.1 AME04703.1 AME04703.1 AME03028.1 AME03028.1 AME03071.1 AME03071.1 AME03073.1 AME03073.1 AME03076.1 AME03076.1 AME04705.1 AME04705.1 AME03080.1 AME03080.1 AME03112.1 AME03112.1 AME03117.1 AME03117.1 deoD deoD AME03154.1 AME03154.1 AME03158.1 AME03158.1 AME03169.1 AME03169.1 AME03238.1 AME03238.1 AME03239.1 AME03239.1 rnhA rnhA pfkA pfkA AME03302.1 AME03302.1 AME03349.1 AME03349.1 AME03357.1 AME03357.1 AME03358.1 AME03358.1 AME03363.1 AME03363.1 AME03389.1 AME03389.1 AME03390.1 AME03390.1 AME03397.1 AME03397.1 AME03401.1 AME03401.1 AME03424.1 AME03424.1 AME03447.1 AME03447.1 AME03450.1 AME03450.1 AME03462.1 AME03462.1 AME03466.1 AME03466.1 AME03469.1 AME03469.1 fucI fucI AME03490.1 AME03490.1 phnW phnW pfkA-2 pfkA-2 AME03554.1 AME03554.1 AME03585.1 AME03585.1 nagB nagB kduI kduI AME03684.1 AME03684.1 ade ade AXE86_06235 AXE86_06235 deoC deoC AME03707.1 AME03707.1 AME03762.1 AME03762.1 AME03765.1 AME03765.1 AME03769.1 AME03769.1 AME03775.1 AME03775.1 rbsK rbsK AME03790.1 AME03790.1 AME04755.1 AME04755.1 csrA csrA AME03930.1 AME03930.1 AME03950.1 AME03950.1 AME03979.1 AME03979.1 AME03982.1 AME03982.1 rny rny AME04095.1 AME04095.1 AME04107.1 AME04107.1 AME04769.1 AME04769.1 AME04173.1 AME04173.1 pgk pgk tpiA tpiA gpmI gpmI AME04207.1 AME04207.1 AME04216.1 AME04216.1 deoD-2 deoD-2 deoB deoB AME04234.1 AME04234.1 eno eno AME04280.1 AME04280.1 rph rph AME04285.1 AME04285.1 AME04318.1 AME04318.1 AME04416.1 AME04416.1 AME04419.1 AME04419.1 xseA xseA xseB xseB AME04452.1 AME04452.1 AME04541.1 AME04541.1 pnp pnp AME04629.1 AME04629.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (223 aa)
surEAcid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (253 aa)
AME02630.1Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (259 aa)
AME02657.1N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
hslVATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (179 aa)
AME04684.1Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AME02769.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AXE86_01110Carbamoylphosphate synthase large subunit; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
lonLon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (772 aa)
AME04692.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AME02856.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (236 aa)
ftsHGlycosyl transferase family 2; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (664 aa)
AME02904.1Tetrapyrrole methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AME02980.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
AME02984.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa)
AME03011.1Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (150 aa)
AME03014.1Metal-dependent hydrolase; Catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0173 family. (225 aa)
AME04703.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
AME03028.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
AME03071.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (373 aa)
AME03073.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (373 aa)
AME03076.1Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AME04705.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AME03080.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
AME03112.1Alpha-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (741 aa)
AME03117.1Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1043 aa)
deoDPurine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
AME03154.1DJ-1/PfpI family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
AME03158.1Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
AME03169.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
AME03238.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
AME03239.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (217 aa)
pfkAATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)
AME03302.1Cell wall hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
AME03349.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)
AME03357.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
AME03358.1Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
AME03363.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AME03389.1glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (375 aa)
AME03390.1methylmalonyl-CoA decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
AME03397.1Addiction module protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
AME03401.1Deoxyguanosinetriphosphate triphosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dGTPase family. Type 2 subfamily. (335 aa)
AME03424.1Hopanoid biosynthesis associated protein HpnK; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AME03447.12-oxoglutarate ferredoxin oxidoreductase subunit beta; Catalyzes the coenzyme A-dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AME03450.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
AME03462.1Addiction module protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
AME03466.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AME03469.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (596 aa)
AME03490.1Fuculose phosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
phnW2-aminoethylphosphonate--pyruvate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. (364 aa)
pfkA-2ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
AME03554.1ATP-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
AME03585.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (265 aa)
kduI5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (280 aa)
AME03684.1Beta-mannosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 26 family. (453 aa)
adeAdenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (577 aa)
AXE86_06235Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
deoC2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (216 aa)
AME03707.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
AME03762.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
AME03765.1Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
AME03769.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
AME03775.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
AME03790.1Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
AME04755.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
csrACarbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (74 aa)
AME03930.11-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (302 aa)
AME03950.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (140 aa)
AME03979.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AME03982.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
rnyRibonuclease Y; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (522 aa)
AME04095.1Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AME04107.1N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AME04769.1Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AME04173.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (405 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (518 aa)
AME04207.1Hexokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AME04216.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
deoD-2Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (394 aa)
AME04234.1Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
AME04280.1Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (248 aa)
AME04285.1Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (208 aa)
AME04318.1N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AME04416.1Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AME04419.1Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (326 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (402 aa)
xseBExodeoxyribonuclease VII; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (78 aa)
AME04452.1phenylacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
AME04541.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (689 aa)
AME04629.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 713030
Other names: S. sp. oral taxon 136, Selenomonas sp. oral taxon 136
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