STRINGSTRING
AME02822.1 AME02822.1 AME02902.1 AME02902.1 AME02984.1 AME02984.1 proC proC AME04703.1 AME04703.1 AME03071.1 AME03071.1 AME03073.1 AME03073.1 AME03081.1 AME03081.1 AME03082.1 AME03082.1 asd asd dapB dapB AME03115.1 AME03115.1 AME03122.1 AME03122.1 ilvC ilvC AME03209.1 AME03209.1 hldD hldD AME03451.1 AME03451.1 AME03580.1 AME03580.1 AME04738.1 AME04738.1 AME03627.1 AME03627.1 AME03725.1 AME03725.1 sucD sucD AME03819.1 AME03819.1 AME04755.1 AME04755.1 AME03845.1 AME03845.1 AME03846.1 AME03846.1 AME03851.1 AME03851.1 AME03853.1 AME03853.1 AME03865.1 AME03865.1 AME04758.1 AME04758.1 folD folD rex rex AME04121.1 AME04121.1 gmd gmd AME04187.1 AME04187.1 fcl fcl AME04195.1 AME04195.1 AME04199.1 AME04199.1 AME04212.1 AME04212.1 AME04213.1 AME04213.1 AME04217.1 AME04217.1 AME04339.1 AME04339.1 AME04371.1 AME04371.1 AME04379.1 AME04379.1 AME04419.1 AME04419.1 AME04478.1 AME04478.1 AME04520.1 AME04520.1 AME04552.1 AME04552.1 AME04596.1 AME04596.1 ahcY ahcY argC argC AME04643.1 AME04643.1 hemA hemA AME02623.1 AME02623.1 mdh mdh aroE aroE AME02769.1 AME02769.1 AME02776.1 AME02776.1 mtlD mtlD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AME02822.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (335 aa)
AME02902.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
AME02984.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa)
AME04703.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
AME03071.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (373 aa)
AME03073.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (373 aa)
AME03081.1Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AME03082.1Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (262 aa)
AME03115.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa)
AME03122.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
AME03209.1Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (326 aa)
hldDADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (323 aa)
AME03451.1L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. (319 aa)
AME03580.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AME04738.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
AME03627.1Gluconate 5-dehydrogenase; Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
AME03725.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa)
AME03819.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
AME04755.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
AME03845.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (354 aa)
AME03846.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
AME03851.1CDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
AME03853.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AME03865.1UDP-N-acetylglucosamine 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AME04758.1NAD(P)-dependent oxidoreductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (295 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
rexRedox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (227 aa)
AME04121.1NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
gmdGDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (342 aa)
AME04187.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (339 aa)
fclGDP-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (311 aa)
AME04195.1Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
AME04199.1Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
AME04212.1Gluconate 2-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
AME04213.13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AME04217.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (346 aa)
AME04339.1beta-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
AME04371.1Arogenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AME04379.1cobalt-precorrin-6A/precorrin-6x reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AME04419.1Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (326 aa)
AME04478.1Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
AME04520.1Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AME04552.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)
AME04596.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (413 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa)
AME04643.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (453 aa)
AME02623.1Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (316 aa)
aroEIron transporter; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (288 aa)
AME02769.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
AME02776.1Saccharopine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
mtlDMannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
Your Current Organism:
Selenomonas
NCBI taxonomy Id: 713030
Other names: S. sp. oral taxon 136, Selenomonas sp. oral taxon 136
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