(28 nodes) Pentose phosphate pathway network (Selenomonas)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AME02856.1	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (236 aa)
	AME02980.1	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
	pfp	6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (420 aa)
	AME04703.1	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
	fbp	Protein tyrosine phosphatase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (632 aa)
	AME04705.1	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
	AME03080.1	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
	pfkA	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (321 aa)
	pfkA-2	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
	AME04739.1	2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
	AME03625.1	2-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
	deoC	2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (216 aa)
	AME03726.1	Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
	AME03765.1	Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
	rbsK	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
	AME03790.1	Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
	AME04754.1	PTS mannose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
	AME03818.1	PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
	AME03841.1	Gluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family. (516 aa)
	AME04755.1	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
	AME04771.1	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
	AME04772.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
	deoB	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (394 aa)
	AME04234.1	Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
	prs	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
	AME04629.1	Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
	AME04632.1	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
	AME04633.1	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)

Your Current Organism:

Selenomonas

NCBI taxonomy Id: 713030
Other names: S. sp. oral taxon 136, Selenomonas sp. oral taxon 136

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AME02856.1	AME02980.1	AXE86_01450	AXE86_02115	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.925
AME02856.1	AME03080.1	AXE86_01450	AXE86_02695	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.925
AME02856.1	AME03625.1	AXE86_01450	AXE86_05815	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	2-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.859
AME02856.1	AME04632.1	AXE86_01450	AXE86_11445	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
AME02856.1	AME04633.1	AXE86_01450	AXE86_11450	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
AME02856.1	AME04703.1	AXE86_01450	AXE86_02340	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.925
AME02856.1	AME04705.1	AXE86_01450	AXE86_02690	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
AME02856.1	AME04755.1	AXE86_01450	AXE86_07055	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.925
AME02856.1	AME04771.1	AXE86_01450	AXE86_08915	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
AME02856.1	AME04772.1	AXE86_01450	AXE86_08920	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
AME02980.1	AME02856.1	AXE86_02115	AXE86_01450	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.	0.925
AME02980.1	AME03080.1	AXE86_02115	AXE86_02695	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.912
AME02980.1	AME04632.1	AXE86_02115	AXE86_11445	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AME02980.1	AME04633.1	AXE86_02115	AXE86_11450	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
AME02980.1	AME04703.1	AXE86_02115	AXE86_02340	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.907
AME02980.1	AME04705.1	AXE86_02115	AXE86_02690	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AME02980.1	AME04755.1	AXE86_02115	AXE86_07055	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.907
AME02980.1	AME04771.1	AXE86_02115	AXE86_08915	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
AME02980.1	AME04772.1	AXE86_02115	AXE86_08920	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
AME02980.1	deoB	AXE86_02115	AXE86_09120	Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.	0.905