STRINGSTRING
ppiB ppiB pnp pnp deaD deaD rph rph rnt rnt rnd rnd rluC rluC rne rne srmB srmB HI_0424 HI_0424 rsmB rsmB rlmB rlmB rnr rnr rhlB rhlB hrpA hrpA engB engB HI_1146 HI_1146 rlmE rlmE rng rng orn orn rnb rnb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppiBPeptidyl-prolyl cis-trans isomerase B (ppiB); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (169 aa)
pnpPolynucleotide phosphorylase (pnp); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (709 aa)
deaDATP-dependent RNA helicase (deaD); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (613 aa)
rphRibonuclease PH (rph); Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
rntRibonuclease T (rnt); Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (229 aa)
rndRibonuclease D (rnd); Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (399 aa)
rluCConserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. (322 aa)
rneRibonuclease E (rne); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (951 aa)
srmBATP-dependent RNA helicase (srmB); DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (439 aa)
HI_0424rRNA methylase, putative; Similar to SP:P33635 GB:U00096 PID:1788935 percent identity: 43.03; identified by sequence similarity; putative; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (351 aa)
rsmBSun protein (sun); Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (451 aa)
rlmBConserved hypothetical protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (246 aa)
rnrVirulence-associated protein (vacB); 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (782 aa)
rhlBATP-dependent RNA helicase (rhlB); DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (418 aa)
hrpAATP-dependent helicase (hrpa); Similar to SP:P43329 PID:806328 GB:U00096 PID:1742299 PID:1742304 percent identity: 70.29; identified by sequence similarity; putative. (1304 aa)
engBConserved hypothetical GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (205 aa)
HI_1146Conserved hypothetical protein; Displays ATPase and GTPase activities. (289 aa)
rlmECell division protein (ftsJ); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (209 aa)
rngCytoplasmic axial filament protein (cafA); Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). (491 aa)
ornConserved hypothetical protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (182 aa)
rnbExoribonuclease II (rnb); Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity). (659 aa)
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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