STRINGSTRING
EHQ26710.1 EHQ26710.1 EHQ31094.1 EHQ31094.1 ackA-3 ackA-3 EHQ30536.1 EHQ30536.1 EHQ30415.1 EHQ30415.1 EHQ29997.1 EHQ29997.1 ackA-2 ackA-2 accD accD EHQ29770.1 EHQ29770.1 EHQ29663.1 EHQ29663.1 EHQ29312.1 EHQ29312.1 EHQ29299.1 EHQ29299.1 EHQ29048.1 EHQ29048.1 EHQ28919.1 EHQ28919.1 ackA ackA EHQ28541.1 EHQ28541.1 EHQ28524.1 EHQ28524.1 icmF icmF EHQ28291.1 EHQ28291.1 sucD sucD EHQ28221.1 EHQ28221.1 EHQ28016.1 EHQ28016.1 EHQ27946.1 EHQ27946.1 EHQ27642.1 EHQ27642.1 EHQ27640.1 EHQ27640.1 EHQ26936.1 EHQ26936.1 EHQ26810.1 EHQ26810.1 EHQ26809.1 EHQ26809.1 EHQ26635.1 EHQ26635.1 accA accA sucC sucC EHQ25390.1 EHQ25390.1 EHQ25340.1 EHQ25340.1 EHQ25131.1 EHQ25131.1 EHQ24842.1 EHQ24842.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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EHQ26710.1PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099; KEGG: shg:Sph21_2569 dihydrolipoyl dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase. (472 aa)
EHQ31094.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: bts:Btus_2032 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase zinc-binding domain protein. (306 aa)
ackA-3Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
EHQ30536.1PFAM: LD-carboxypeptidase; COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: phe:Phep_2200 peptidase U61 LD-carboxypeptidase A; PFAM: Peptidase S66, LD-carboxypeptidase A; SPTR: Peptidase U61 LD-carboxypeptidase A. (341 aa)
EHQ30415.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (494 aa)
EHQ29997.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (709 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa)
EHQ29770.1Integrase catalytic region; PFAM: Integrase core domain; COGs: COG2801 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: eli:ELI_14900 transposase orfB; PFAM: Integrase, catalytic core; SPTR: Integrase catalytic region. (296 aa)
EHQ29663.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: cpi:Cpin_4348 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase zinc-binding domain protein. (316 aa)
EHQ29312.1KEGG: phe:Phep_0658 hypothetical protein; SPTR: Putative uncharacterized protein. (144 aa)
EHQ29299.1methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: phe:Phep_1564 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Methylmalonyl-CoA epimerase; TIGRFAM: Methylmalonyl-CoA epimerase. (136 aa)
EHQ29048.1acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: phe:Phep_2901 acetyl-CoA acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
EHQ28919.1PFAM: Protein of unknown function (DUF1254); Protein of unknown function (DUF1214); COGs: COG5361 conserved hypothetical protein; InterPro IPR010679:IPR010621; KEGG: ppn:Palpr_1607 hypothetical protein; PFAM: Protein of unknown function DUF1254; Protein of unknown function DUF1214; SPTR: Putative uncharacterized protein. (487 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
EHQ28541.1PFAM: Carboxyl transferase domain; COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: phe:Phep_0639 carboxyl transferase; PFAM: Carboxyl transferase; SPTR: Carboxyl transferase. (513 aa)
EHQ28524.1Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: psn:Pedsa_0439 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase. (463 aa)
icmFmethylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1159 aa)
EHQ28291.1PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR001017:IPR005475:IPR005476; KEGG: phe:Phep_3824 dehydrogenase E1 component; PFAM: Dehydrogenase, E1 component; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; SPTR: Dehydrogenase E1 component. (659 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
EHQ28221.1Hypothetical protein; PFAM: RimK-like ATP-grasp domain; COGs: COG3919 ATP-grasp protein; KEGG: mca:MCA0534 hypothetical protein; SPTR: ATP-grasp protein. (380 aa)
EHQ28016.1PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006158:IPR006159; KEGG: cpi:Cpin_0241 cobalamin B12-binding domain protein; PFAM: Cobalamin (vitamin B12)-binding; SPTR: Cobalamin B12-binding domain protein; TIGRFAM: Methylmalonyl-CoA mutase, C-terminal. (140 aa)
EHQ27946.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: psn:Pedsa_3538 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase zinc-binding domain protein. (331 aa)
EHQ27642.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: cpi:Cpin_3524 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase zinc-binding domain protein. (320 aa)
EHQ27640.1PFAM: LD-carboxypeptidase; COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: shg:Sph21_1426 peptidase U61 LD-carboxypeptidase A; PFAM: Peptidase S66, LD-carboxypeptidase A; SPTR: Peptidase U61 LD-carboxypeptidase A. (299 aa)
EHQ26936.1PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1; COGs: COG1882 Pyruvate-formate lyase; InterPro IPR004184:IPR001150:IPR005949; KEGG: bth:BT_4738 formate acetyltransferase; PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; SPTR: Formate acetyltransferase; TIGRFAM: Formate acetyltransferase. (744 aa)
EHQ26810.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (457 aa)
EHQ26809.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa)
EHQ26635.1Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR004099:IPR006258; KEGG: phe:Phep_3710 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase. (467 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
sucCSuccinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
EHQ25390.1methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR006099; KEGG: phe:Phep_3607 methylmalonyl-CoA mutase large subunit; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; SPTR: Methylmalonyl-CoA mutase; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic. (516 aa)
EHQ25340.1acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
EHQ25131.1Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR001017:IPR005475:IPR005476; KEGG: phe:Phep_1509 transketolase domain-containing protein; PFAM: Transketolase, C-terminal; Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; SPTR: Transketolase domain protein. (809 aa)
EHQ24842.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149; KEGG: cpi:Cpin_4859 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase, zinc-binding; Alcohol dehydrogenase GroES-like; SPTR: Alcohol dehydrogenase zinc-binding domain protein. (322 aa)
Your Current Organism:
Mucilaginibacter paludis
NCBI taxonomy Id: 714943
Other names: M. paludis DSM 18603, Mucilaginibacter paludis DSM 18603, Mucilaginibacter paludis TPT56, Mucilaginibacter paludis str. DSM 18603, Mucilaginibacter paludis strain DSM 18603
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