(35 nodes) VxPx cargo-targeting to cilium, and RAB geranylgeranylation network (Aedes aegypti)

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	AAEL008000	AAEL008000-PA. (548 aa)
	AAEL013769	AAEL013769-PA. (737 aa)
	AAEL013252	AAEL013252-PB. (239 aa)
	AAEL012904	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (443 aa)
	AAEL010432	AAEL010432-PA. (673 aa)
	AAEL010170	Ras-related protein Rab-8A, putative. (208 aa)
	AAEL010005	AAEL010005-PA. (433 aa)
	AAEL009974	AAEL009974-PA. (219 aa)
	AAEL009926	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (896 aa)
	AAEL009832	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (708 aa)
	AAEL009592	AAEL009592-PA. (428 aa)
	AAEL009357	AAEL009357-PA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1792 aa)
	AAEL009342	AAEL009342-PA. (208 aa)
	AAEL009200	AAEL009200-PA. (892 aa)
	AAEL008959	AAEL008959-PA. (219 aa)
	AAEL007525	AAEL007525-PA. (219 aa)
	AAEL007330	Exocyst complex component sec6. (737 aa)
	AAEL006781	AAEL006781-PA. (203 aa)
	AAEL006776	AAEL006776-PA. (505 aa)
	AAEL006185	AAEL006185-PA. (991 aa)
	AAEL005315	AAEL005315-PA. (266 aa)
	AAEL005271	AAEL005271-PA. (351 aa)
	AAEL005069	AAEL005069-PA. (206 aa)
	AAEL005061	AAEL005061-PA. (714 aa)
	AAEL004902	AAEL004902-PA. (213 aa)
	AAEL004329	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (579 aa)
	AAEL003736	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (761 aa)
	AAEL003487	Development and differentiation-enhancing factor, ddef. (1123 aa)
	AAEL002918	AAEL002918-PA. (852 aa)
	AAEL002155	Ras-related protein Rab-10, putative. (204 aa)
	AAEL002066	AAEL002066-PA. (894 aa)
	AAEL001334	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (332 aa)
	AAEL000605	AAEL000605-PA. (532 aa)
	AAEL000421	AAEL000421-PA. (415 aa)
	AAEL009317	RAB family GTPase. (215 aa)

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL000421	AAEL001334	Q17P84	Q17LJ2	AAEL000421-PA.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.973
AAEL000421	AAEL004329	Q17P84	Q17D49	AAEL000421-PA.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.936
AAEL000421	AAEL004902	Q17P84	Q17BP4	AAEL000421-PA.	AAEL004902-PA.	0.454
AAEL000421	AAEL005069	Q17P84	Q17B74	AAEL000421-PA.	AAEL005069-PA.	0.496
AAEL000421	AAEL007525	Q17P84	Q171U7	AAEL000421-PA.	AAEL007525-PA.	0.496
AAEL000421	AAEL008959	Q17P84	Q16XA1	AAEL000421-PA.	AAEL008959-PA.	0.696
AAEL000421	AAEL009317	Q17P84	Q1HQR4	AAEL000421-PA.	RAB family GTPase.	0.612
AAEL000421	AAEL009342	Q17P84	Q16W42	AAEL000421-PA.	AAEL009342-PA.	0.454
AAEL000421	AAEL012904	Q17P84	Q16KQ6	AAEL000421-PA.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.590
AAEL000421	AAEL013252	Q17P84	Q16JQ4	AAEL000421-PA.	AAEL013252-PB.	0.563
AAEL000605	AAEL001334	Q17NP5	Q17LJ2	AAEL000605-PA.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.999
AAEL000605	AAEL002155	Q17NP5	Q17J36	AAEL000605-PA.	Ras-related protein Rab-10, putative.	0.606
AAEL000605	AAEL004329	Q17NP5	Q17D49	AAEL000605-PA.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.986
AAEL000605	AAEL004902	Q17NP5	Q17BP4	AAEL000605-PA.	AAEL004902-PA.	0.626
AAEL000605	AAEL005069	Q17NP5	Q17B74	AAEL000605-PA.	AAEL005069-PA.	0.809
AAEL000605	AAEL007525	Q17NP5	Q171U7	AAEL000605-PA.	AAEL007525-PA.	0.700
AAEL000605	AAEL008959	Q17NP5	Q16XA1	AAEL000605-PA.	AAEL008959-PA.	0.813
AAEL000605	AAEL009317	Q17NP5	Q1HQR4	AAEL000605-PA.	RAB family GTPase.	0.681
AAEL000605	AAEL009342	Q17NP5	Q16W42	AAEL000605-PA.	AAEL009342-PA.	0.454
AAEL000605	AAEL009974	Q17NP5	Q16UA3	AAEL000605-PA.	AAEL009974-PA.	0.606