(10 nodes) U1 snRNP network (Aedes aegypti)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Others

textmining

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Your Input:
	AAEL002980	AAEL002980-PA. (216 aa)
	AAEL013527	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 small [...] (154 aa)
	AAEL011433	Small nuclear ribonucleoprotein Sm D3. (147 aa)
	AAEL011340	U1 small nuclear ribonucleoprotein 70 kd. (189 aa)
	AAEL011233	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (91 aa)
	AAEL009914	Small nuclear ribonucleoprotein Sm D2. (119 aa)
	AAEL008719	Small nuclear ribonucleoprotein G. (76 aa)
	AAEL006840	U2 small nuclear ribonucleoprotein a. (260 aa)
	AAEL001382	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (126 aa)
	AAEL002377	Small nuclear ribonucleoprotein-associated protein. (205 aa)

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL001382	AAEL002377	Q17DD1	Q1HQD9	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Small nuclear ribonucleoprotein-associated protein.	0.999
AAEL001382	AAEL002980	Q17DD1	Q16H40	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	AAEL002980-PA.	0.997
AAEL001382	AAEL006840	Q17DD1	Q174L8	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	U2 small nuclear ribonucleoprotein a.	0.964
AAEL001382	AAEL008719	Q17DD1	Q16XZ1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Small nuclear ribonucleoprotein G.	0.999
AAEL001382	AAEL009914	Q17DD1	Q16UH6	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Small nuclear ribonucleoprotein Sm D2.	0.999
AAEL001382	AAEL011233	Q17DD1	Q16QN6	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.999
AAEL001382	AAEL011340	Q17DD1	Q16QA9	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	U1 small nuclear ribonucleoprotein 70 kd.	0.963
AAEL001382	AAEL011433	Q17DD1	Q16Q31	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	Small nuclear ribonucleoprotein Sm D3.	0.999
AAEL001382	AAEL013527	Q17DD1	Q16IW3	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 small [...]	0.991
AAEL002377	AAEL001382	Q1HQD9	Q17DD1	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.999
AAEL002377	AAEL002980	Q1HQD9	Q16H40	Small nuclear ribonucleoprotein-associated protein.	AAEL002980-PA.	0.997
AAEL002377	AAEL006840	Q1HQD9	Q174L8	Small nuclear ribonucleoprotein-associated protein.	U2 small nuclear ribonucleoprotein a.	0.962
AAEL002377	AAEL008719	Q1HQD9	Q16XZ1	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein G.	0.999
AAEL002377	AAEL009914	Q1HQD9	Q16UH6	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D2.	0.999
AAEL002377	AAEL011233	Q1HQD9	Q16QN6	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.998
AAEL002377	AAEL011340	Q1HQD9	Q16QA9	Small nuclear ribonucleoprotein-associated protein.	U1 small nuclear ribonucleoprotein 70 kd.	0.948
AAEL002377	AAEL011433	Q1HQD9	Q16Q31	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D3.	0.997
AAEL002377	AAEL013527	Q1HQD9	Q16IW3	Small nuclear ribonucleoprotein-associated protein.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 small [...]	0.994
AAEL002980	AAEL001382	Q16H40	Q17DD1	AAEL002980-PA.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.997
AAEL002980	AAEL002377	Q16H40	Q1HQD9	AAEL002980-PA.	Small nuclear ribonucleoprotein-associated protein.	0.997