40 items (Aedes aegypti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	J9HGQ4_AEDAE	AAEL017031-PA; Belongs to the cyclic nucleotide phosphodiesterase family. (378 aa)
	J9HZD6_AEDAE	Phosphoinositide phospholipase C. (536 aa)
	AAEL004185	AAEL004185-PA. (299 aa)
	AAEL015141	Tyrosyl-DNA phosphodiesterase. (624 aa)
	AAEL014346	AAEL014346-PA. (91 aa)
	AAEL014352	AAEL014352-PA. (640 aa)
	AAEL013900	Phosphodiesterase. (767 aa)
	AAEL013879	AAEL013879-PA. (373 aa)
	AAEL013747	AAEL013747-PA. (474 aa)
	AAEL013717	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (629 aa)
	AAEL013473	Phosphodiesterase. (872 aa)
	AAEL013342	AAEL013342-PA; Belongs to the cyclic nucleotide phosphodiesterase family. (770 aa)
	AAEL012548	AAEL012548-PA. (328 aa)
	AAEL011385	AAEL011385-PA. (328 aa)
	AAEL011172	AAEL011172-PA. (299 aa)
	AAEL010781	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (612 aa)
	AAEL010678	AAEL010678-PA. (381 aa)
	AAEL010541	AAEL010541-PA. (184 aa)
	AAEL010539	Phosphodiesterase. (526 aa)
	AAEL010124	Phosphoinositide phospholipase C. (774 aa)
	AAEL009630	Phosphodiesterase. (1022 aa)
	AAEL009380	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1082 aa)
	AAEL009111	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (634 aa)
	AAEL008246	Phosphoinositide phospholipase C. (1022 aa)
	AAEL007412	Sphingomyelin phosphodiesterase. (532 aa)
	AAEL006380	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (633 aa)
	AAEL006375	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (634 aa)
	AAEL006381	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (629 aa)
	AAEL005600	AAEL005600-PA. (347 aa)
	AAEL004520	Phosphodiesterase. (1087 aa)
	AAEL004431	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1210 aa)
	AAEL003698	AAEL003698-PA. (886 aa)
	AAEL003402	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (801 aa)
	AAEL002910	AAEL002910-PA. (765 aa)
	AAEL002413	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (633 aa)
	AAEL002009	AAEL002009-PA. (420 aa)
	AAEL001629	Phosphodiesterase. (734 aa)
	AAEL001492	Phosphodiesterase. (502 aa)
	AAEL001241	AAEL001241-PA. (337 aa)
	AAEL000264	Phospholipase. (1184 aa)

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL000264	AAEL008246	Q17PR0	Q16ZC0	Phospholipase.	Phosphoinositide phospholipase C.	0.463
AAEL000264	AAEL009380	Q17PR0	Q16W09	Phospholipase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.481
AAEL000264	AAEL011385	Q17PR0	Q16Q75	Phospholipase.	AAEL011385-PA.	0.446
AAEL001492	AAEL010539	Q17L35	Q16SN9	Phosphodiesterase.	Phosphodiesterase.	0.404
AAEL001492	AAEL010541	Q17L35	Q16SN8	Phosphodiesterase.	AAEL010541-PA.	0.404
AAEL001492	AAEL013342	Q17L35	Q16JF3	Phosphodiesterase.	AAEL013342-PA; Belongs to the cyclic nucleotide phosphodiesterase family.	0.426
AAEL001629	AAEL013342	Q17KM9	Q16JF3	Phosphodiesterase.	AAEL013342-PA; Belongs to the cyclic nucleotide phosphodiesterase family.	0.589
AAEL002009	AAEL002413	Q17JK7	Q17IB7	AAEL002009-PA.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.919
AAEL002009	AAEL002910	Q17JK7	Q17GU0	AAEL002009-PA.	AAEL002910-PA.	0.563
AAEL002009	AAEL003402	Q17JK7	Q17FG9	AAEL002009-PA.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.919
AAEL002009	AAEL007412	Q17JK7	Q172E7	AAEL002009-PA.	Sphingomyelin phosphodiesterase.	0.561
AAEL002009	AAEL008246	Q17JK7	Q16ZC0	AAEL002009-PA.	Phosphoinositide phospholipase C.	0.459
AAEL002009	AAEL009111	Q17JK7	Q16WS5	AAEL002009-PA.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.919
AAEL002009	AAEL009380	Q17JK7	Q16W09	AAEL002009-PA.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.459
AAEL002009	AAEL013717	Q17JK7	Q16IC9	AAEL002009-PA.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.919
AAEL002413	AAEL002009	Q17IB7	Q17JK7	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	AAEL002009-PA.	0.919
AAEL002413	AAEL003402	Q17IB7	Q17FG9	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.910
AAEL002413	AAEL009111	Q17IB7	Q16WS5	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.905
AAEL002413	AAEL013717	Q17IB7	Q16IC9	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	0.905
AAEL002910	AAEL002009	Q17GU0	Q17JK7	AAEL002910-PA.	AAEL002009-PA.	0.563