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AAEL011871 AAEL011871 AAEL011746 AAEL011746 AAEL011683 AAEL011683 AAEL011606 AAEL011606 AAEL008771 AAEL008771 AAEL011437 AAEL011437 AAEL011406 AAEL011406 AAEL011381 AAEL011381 AAEL011276 AAEL011276 AAEL011157 AAEL011157 AAEL011110 AAEL011110 AAEL011010 AAEL011010 AAEL010608 AAEL010608 AAEL010519 AAEL010519 AAEL010330 AAEL010330 AAEL010230 AAEL010230 AAEL010143 AAEL010143 AAEL000151 AAEL000151 AAEL009961 AAEL009961 NU4M_AEDAE NU4M_AEDAE AAEL009066 AAEL009066 AAEL008216 AAEL008216 AAEL008166 AAEL008166 AAEL008167 AAEL008167 AAEL008059 AAEL008059 AAEL008072 AAEL008072 AAEL007707 AAEL007707 AAEL007681 AAEL007681 AAEL007526 AAEL007526 AAEL007490 AAEL007490 AAEL006779 AAEL006779 AAEL006721 AAEL006721 AAEL006362 AAEL006362 AAEL006290 AAEL006290 AAEL006000 AAEL006000 AAEL005946 AAEL005946 AAEL005866 AAEL005866 AAEL005620 AAEL005620 AAEL005552 AAEL005552 AAEL005429 AAEL005429 AAEL005269 AAEL005269 AAEL005170 AAEL005170 AAEL004670 AAEL004670 AAEL004078 AAEL004078 AAEL004051 AAEL004051 AAEL004081 AAEL004081 AAEL004060 AAEL004060 AAEL003734 AAEL003734 AAEL003675 AAEL003675 AAEL003452 AAEL003452 AAEL003393 AAEL003393 AAEL002956 AAEL002956 AAEL002897 AAEL002897 AAEL002827 AAEL002827 AAEL002812 AAEL002812 AAEL002764 AAEL002764 AAEL002504 AAEL002504 AAEL002431 AAEL002431 AAEL002383 AAEL002383 AAEL002016 AAEL002016 AAEL001880 AAEL001880 AAEL001773 AAEL001773 AAEL001789 AAEL001789 AAEL001718 AAEL001718 AAEL001164 AAEL001164 AAEL000986 AAEL000986 AAEL000929 AAEL000929 AAEL000877 AAEL000877 AAEL000766 AAEL000766 AAEL000740 AAEL000740 AAEL000619 AAEL000619 AAEL000526 AAEL000526 AAEL000454 AAEL000454 AAEL000268 AAEL000268 AAEL000182 AAEL000182 AAEL000159 AAEL000159 AAEL009257 AAEL009257 AAEL014889 AAEL014889 mt:CoIII mt:CoIII mt:CoI mt:CoI mt:ND2 mt:ND2 AAEL002737 AAEL002737 AAEL012950 AAEL012950 mt:ND5 mt:ND5 mt:ND4 mt:ND4 AAEL006833 AAEL006833 AAEL014505 AAEL014505 AAEL001210 AAEL001210 SGP2D7 SGP2D7 AAEL008871 AAEL008871 AAEL005508 AAEL005508 AAEL003234 AAEL003234 AAEL007752 AAEL007752 AAEL007868 AAEL007868 mt:ND4L mt:ND4L mt:Cyt-b mt:Cyt-b J9EAU0_AEDAE J9EAU0_AEDAE J9HFH0_AEDAE J9HFH0_AEDAE J9HJ41_AEDAE J9HJ41_AEDAE AAEL010814 AAEL010814 AAEL010823 AAEL010823 AAEL010754 AAEL010754 AAEL008002 AAEL008002 AAEL004829 AAEL004829 AAEL003090 AAEL003090 AAEL015315 AAEL015315 AAEL015292 AAEL015292 AAEL014681 AAEL014681 AAEL014673 AAEL014673 AAEL014532 AAEL014532 AAEL014201 AAEL014201 AAEL003031 AAEL003031 AAEL013870 AAEL013870 AAEL013009 AAEL013009 AAEL008697 AAEL008697 AAEL012897 AAEL012897 AAEL012716 AAEL012716 AAEL012614 AAEL012614 AAEL012552 AAEL012552 AAEL012498 AAEL012498 AAEL012454 AAEL012454 AAEL012117 AAEL012117 AAEL011789 AAEL011789
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AAEL011871AAEL011871-PA. (306 aa)
AAEL011746Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (449 aa)
AAEL011683AAEL011683-PA. (68 aa)
AAEL011606AAEL011606-PB. (210 aa)
AAEL008771AAEL008771-PA. (100 aa)
AAEL011437AAEL011437-PA. (89 aa)
AAEL011406AAEL011406-PA. (152 aa)
AAEL011381AAEL011381-PA; Belongs to the complex I 49 kDa subunit family. (468 aa)
AAEL011276AAEL011276-PA; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
AAEL011157AAEL011157-PA. (100 aa)
AAEL011110AAEL011110-PA. (101 aa)
AAEL011010AAEL011010-PA. (106 aa)
AAEL010608Succinate dehydrogenase (quinone); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (659 aa)
AAEL010519Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (177 aa)
AAEL010330Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (289 aa)
AAEL010230AAEL010230-PA; Belongs to the complex I LYR family. (146 aa)
AAEL010143Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (370 aa)
AAEL000151AAEL000151-PA. (203 aa)
AAEL009961AAEL009961-PA; Belongs to the complex I LYR family. (117 aa)
NU4M_AEDAENADH-ubiquinone oxidoreductase chain 4. (79 aa)
AAEL009066AAEL009066-PA. (162 aa)
AAEL008216Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (901 aa)
AAEL008166AAEL008166-PA. (419 aa)
AAEL008167AAEL008167-PB. (503 aa)
AAEL008059AAEL008059-PA. (60 aa)
AAEL008072AAEL008072-PA; Belongs to the complex I 20 kDa subunit family. (215 aa)
AAEL007707Malate dehydrogenase. (338 aa)
AAEL007681NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (487 aa)
AAEL007526Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (588 aa)
AAEL007490AAEL007490-PA. (70 aa)
AAEL006779AAEL006779-PA. (235 aa)
AAEL0067212-oxoglutarate dehydrogenase. (1057 aa)
AAEL006362AAEL006362-PA; Belongs to the mitochondrial carrier (TC 2.A.29) family. (681 aa)
AAEL006290AAEL006290-PA. (511 aa)
AAEL006000AAEL006000-PA. (74 aa)
AAEL005946NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (114 aa)
AAEL005866Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (161 aa)
AAEL005620AAEL005620-PA. (100 aa)
AAEL005552Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (421 aa)
AAEL005429AAEL005429-PA. (904 aa)
AAEL005269Ubiquinol-cytochrome c reductase complex core protein. (441 aa)
AAEL005170Cytochrome c oxidase subunit iv. (409 aa)
AAEL004670AAEL004670-PA. (96 aa)
AAEL004078Succinyl-CoA synthetase beta chain. (214 aa)
AAEL004051AAEL004051-PA. (253 aa)
AAEL004081AAEL004081-PA. (186 aa)
AAEL004060AAEL004060-PB. (59 aa)
AAEL003734Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (803 aa)
AAEL003675Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (266 aa)
AAEL003452AAEL003452-PB. (199 aa)
AAEL003393ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (504 aa)
AAEL002956Probable citrate synthase 1, mitochondrial. (467 aa)
AAEL002897AAEL002897-PA. (101 aa)
AAEL002827ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (504 aa)
AAEL002812AAEL002812-PA; Belongs to the complex I LYR family. (84 aa)
AAEL002764Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase. (491 aa)
AAEL002504ATP synthase delta chain, mitochondrial. (173 aa)
AAEL002431AAEL002431-PA. (77 aa)
AAEL002383Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (154 aa)
AAEL002016Disulfide oxidoreductase. (718 aa)
AAEL001880AAEL001880-PA. (98 aa)
AAEL001773AAEL001773-PA. (159 aa)
AAEL001789AAEL001789-PA. (186 aa)
AAEL001718AAEL001718-PA. (103 aa)
AAEL001164NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
AAEL000986NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (174 aa)
AAEL000929Cytochrome c oxidase, subunit VIA, putative; Belongs to the cytochrome c oxidase subunit 6A family. (111 aa)
AAEL000877AAEL000877-PA. (102 aa)
AAEL000766Ubiquinol cytochrome C oxidoreductase-subunit 6.4kD-subunit, putative. (54 aa)
AAEL000740AAEL000740-PA. (77 aa)
AAEL000619AAEL000619-PA. (100 aa)
AAEL000526AAEL000526-PA. (76 aa)
AAEL000454Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa)
AAEL000268AAEL000268-PA. (352 aa)
AAEL000182AAEL000182-PA. (56 aa)
AAEL000159AAEL000159-PA. (273 aa)
AAEL009257Mitochondrial cytochrome c oxidase subunit VIC. (78 aa)
AAEL014889Mitochondrial NADH:ubiquinone oxidoreductase NDUFA8/PGIV/19 kDa subunit. (175 aa)
mt:CoIIICytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (262 aa)
mt:CoICytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
mt:ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (341 aa)
AAEL002737Cytochrome c oxidase, subunit VIIC, putative. (67 aa)
AAEL012950NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (407 aa)
mt:ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (580 aa)
mt:ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (447 aa)
AAEL006833Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (327 aa)
AAEL014505Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (177 aa)
AAEL001210NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (123 aa)
SGP2D7Mitochondrial cytochrome c oxidase subunit VA. (152 aa)
AAEL008871Mitochondrial succinate dehydrogenase cytochrome b subunit. (171 aa)
AAEL005508NADH:ubiquinone oxidoreductase NDUFV2/24 kDa subunit. (240 aa)
AAEL003234Cytochrome c oxidase subunit VIa/COX13; Belongs to the cytochrome c oxidase subunit 6A family. (109 aa)
AAEL007752Cytochrome c oxidase subunit VIIa. (90 aa)
AAEL007868Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (110 aa)
mt:ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
mt:Cyt-bCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (378 aa)
J9EAU0_AEDAEAAEL017086-PA. (205 aa)
J9HFH0_AEDAEAAEL005143-PB. (82 aa)
J9HJ41_AEDAECytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (107 aa)
AAEL010814AAEL010814-PA. (393 aa)
AAEL010823AAEL010823-PA. (210 aa)
AAEL010754AAEL010754-PA. (86 aa)
AAEL008002AAEL008002-PA. (157 aa)
AAEL004829AAEL004829-PA. (157 aa)
AAEL003090AAEL003090-PA. (545 aa)
AAEL015315Malate synthase. (295 aa)
AAEL015292AAEL015292-PA; Belongs to the complex I LYR family. (117 aa)
AAEL014681AAEL014681-PA. (106 aa)
AAEL014673NADH:ubiquinone dehydrogenase, putative. (130 aa)
AAEL014532AAEL014532-PA. (103 aa)
AAEL014201AAEL014201-PA. (317 aa)
AAEL003031AAEL003031-PA. (92 aa)
AAEL013870AAEL013870-PA. (292 aa)
AAEL013009Cytochrome c oxidase subunit iv. (177 aa)
AAEL008697Cytochrome c oxidase, subunit VB, putative. (119 aa)
AAEL012897Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (788 aa)
AAEL012716Chaperone protein, putative. (317 aa)
AAEL012614NADP-specific isocitrate dehydrogenase. (323 aa)
AAEL012552AAEL012552-PA; Belongs to the complex I 75 kDa subunit family. (730 aa)
AAEL012498AAEL012498-PA. (860 aa)
AAEL012454AAEL012454-PA. (95 aa)
AAEL012117AAEL012117-PA; Belongs to the mitochondrial carrier (TC 2.A.29) family. (350 aa)
AAEL011789Probable citrate synthase 2, mitochondrial. (467 aa)
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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