(131 nodes) Regulation of neurogenesis network (Aedes aegypti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AAEL000623	AAEL000623-PA. (545 aa)
	AAEL000774	AAEL000774-PA. (407 aa)
	AAEL000786	AAEL000786-PA. (370 aa)
	AAEL013544	AAEL013544-PA. (427 aa)
	AAEL001190	AAEL001190-PA. (358 aa)
	AAEL001428	Transcription factor Hairy, putative. (298 aa)
	AAEL001476	AAEL001476-PA. (551 aa)
	AAEL001473	AAEL001473-PA. (1069 aa)
	AAEL001682	AAEL001682-PA. (325 aa)
	J9HFS6_AEDAE	AAEL017280-PA. (2047 aa)
	J9HTL1_AEDAE	AAEL017286-PA. (239 aa)
	AAEL801209	POU domain protein. (502 aa)
	AAEL009655	AAEL009655-PA. (172 aa)
	AAEL009649	AAEL009649-PA. (512 aa)
	AAEL003063	AAEL003063-PA; Belongs to the semaphorin family. (776 aa)
	AAEL015320	AAEL015320-PA. (636 aa)
	AAEL015035	Transcription enhancer factor, putative. (275 aa)
	AAEL014907	AAEL014907-PA. (601 aa)
	AAEL014670	AAEL014670-PA. (396 aa)
	AAEL014597	AAEL014597-PA. (675 aa)
	AAEL014559	AAEL014559-PA. (142 aa)
	AAEL014545	Unkempt protein. (426 aa)
	AAEL014042	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (445 aa)
	AAEL014018	AAEL014018-PA. (299 aa)
	AAEL014022	AAEL014022-PA. (184 aa)
	AAEL013826	Serine/threonine protein kinase lats. (973 aa)
	AAEL013589	AAEL013589-PA. (349 aa)
	AAEL001104	AAEL001104-PA. (393 aa)
	AAEL013390	AAEL013390-PA. (571 aa)
	AAEL013353	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	AAEL013186	Heparan sulphate sulfotransferase. (315 aa)
	AAEL013068	Serine/threonine-protein phosphatase. (309 aa)
	AAEL012456	AAEL012456-PA. (609 aa)
	AAEL005480	AAEL005480-PA. (343 aa)
	AAEL011857	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (568 aa)
	AAEL011851	AAEL011851-PA. (298 aa)
	AAEL011602	AAEL011602-PA. (376 aa)
	AAEL011604	AAEL011604-PA. (3652 aa)
	AAEL011396	Neurogenic locus delta protein. (826 aa)
	AAEL011215	F-box and WD40 domain protein 7 (fbw7). (1111 aa)
	AAEL011117	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (431 aa)
	AAEL011114	AAEL011114-PA. (548 aa)
	AAEL011056	Transcription factor HES-1 (Hairy and enhancer of split 1), putative. (355 aa)
	AAEL010908	AAEL010908-PA. (493 aa)
	AAEL010907	AAEL010907-PA. (316 aa)
	AAEL010871	AAEL010871-PA. (1183 aa)
	AAEL010873	AAEL010873-PA. (568 aa)
	AAEL010513	AAEL010513-PA. (507 aa)
	AAEL010425	AAEL010425-PA. (123 aa)
	AAEL010352	AAEL010352-PA. (122 aa)
	AAEL010210	Neurogenic locus notch (notch). (2599 aa)
	AAEL010057	AAEL010057-PA. (375 aa)
	AAEL009975	AAEL009975-PA. (295 aa)
	AAEL009947	Homeotic antennapedia protein, putative. (325 aa)
	AAEL009880	AAEL009880-PA; Belongs to the protein kinase superfamily. (405 aa)
	AAEL009777	AAEL009777-PA. (367 aa)
	AAEL009737	AAEL009737-PA. (784 aa)
	AAEL009390	AAEL009390-PA. (173 aa)
	AAEL009326	AAEL009326-PA. (717 aa)
	AAEL008804	AAEL008804-PA. (342 aa)
	AAEL008819	AAEL008819-PA. (495 aa)
	AAEL008774	AAEL008774-PA. (90 aa)
	AAEL008696	Mothers against decapentaplegic homolog. (409 aa)
	AAEL008398	AAEL008398-PA. (2327 aa)
	AAEL008350	AAEL008350-PA. (277 aa)
	AAEL008346	AAEL008346-PA. (289 aa)
	AAEL008234	AAEL008234-PA. (565 aa)
	AAEL008179	AAEL008179-PA. (182 aa)
	AAEL007804	AAEL007804-PA. (1026 aa)
	AAEL007799	AAEL007799-PA. (519 aa)
	AAEL007682	AAEL007682-PA. (165 aa)
	AAEL007484	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (777 aa)
	AAEL007303	AAEL007303-PA. (156 aa)
	AAEL007268	AAEL007268-PA. (1086 aa)
	AAEL007233	AAEL007233-PA. (498 aa)
	AAEL007208	AAEL007208-PA. (472 aa)
	AAEL007190	AAEL007190-PA. (594 aa)
	AAEL006831	Achaete-scute complex protein T3, putative. (221 aa)
	AAEL006801	Vang-like protein. (562 aa)
	AAEL006682	AAEL006682-PA. (142 aa)
	AAEL006539	AAEL006539-PA. (596 aa)
	AAEL006145	AAEL006145-PA. (1217 aa)
	AAEL006069	AAEL006069-PA. (594 aa)
	AAEL006018	AAEL006018-PB. (591 aa)
	AAEL005993	AAEL005993-PA; Belongs to the semaphorin family. (709 aa)
	AAEL005861	Vacuolar sorting protein (vps). (2070 aa)
	AAEL005814	AAEL005814-PA. (1611 aa)
	AAEL005646	AAEL005646-PA. (373 aa)
	AAEL005544	AAEL005544-PA. (824 aa)
	AAEL005549	AAEL005549-PA. (383 aa)
	AAEL004952	Protein N-terminal asparagine amidohydrolase, putative. (310 aa)
	AAEL004942	AAEL004942-PB. (1455 aa)
	AAEL004918	AAEL004918-PA. (904 aa)
	AAEL004586	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (487 aa)
	AAEL004358	AAEL004358-PA. (1171 aa)
	AAEL004371	AAEL004371-PA. (371 aa)
	AAEL004258	AAEL004258-PA. (676 aa)
	AAEL004246	Still life, sif. (1869 aa)
	AAEL004133	AAEL004133-PA. (1285 aa)
	AAEL004106	AAEL004106-PA. (343 aa)
	AAEL003845	Ets domain-containing protein. (417 aa)
	AAEL003682	AAEL003682-PA. (439 aa)
	AAEL003684	AAEL003684-PA. (675 aa)
	AAEL003454	AAEL003454-PA. (222 aa)
	AAEL003373	AAEL003373-PA. (1116 aa)
	AAEL003364	AAEL003364-PA. (236 aa)
	AAEL003371	F-box and WD-40 domain protein. (524 aa)
	AAEL003169	AAEL003169-PA. (1033 aa)
	AAEL003124	AAEL003124-PA. (383 aa)
	AAEL003109	AAEL003109-PA. (548 aa)
	AAEL002885	Protein kinase c zeta and iota isoform; Belongs to the protein kinase superfamily. (477 aa)
	AAEL002919	AAEL002919-PA. (225 aa)
	AAEL002829	AAEL002829-PA. (7342 aa)
	AAEL002839	AAEL002839-PA. (551 aa)
	AAEL002845	AAEL002845-PA. (97 aa)
	AAEL002787	AAEL002787-PA. (256 aa)
	AAEL002769	Homeobox protein prospero/prox-1. (990 aa)
	AAEL002653	AAEL002653-PA. (677 aa)
	AAEL002346	AAEL002346-PB. (1866 aa)
	AAEL002129	AAEL002129-PA. (347 aa)
	AAEL001727	AAEL001727-PA. (237 aa)
	AAEL001711	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
	AAEL010012	Vesicle coat complex COPII GTPase subunit SAR1; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
	AAEL014566	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (571 aa)
	AAEL015522	AAEL015522-PA. (856 aa)
	AAEL015523	AAEL015523-PA. (194 aa)
	AAEL015564	AAEL015564-PA. (235 aa)
	GPRSTN	AAEL000246-PA; Belongs to the G-protein coupled receptor 2 family. (3468 aa)
	AAEL000577	AAEL000577-PA. (588 aa)
	AAEL000584	AAEL000584-PA. (464 aa)
	AAEL000631	AAEL000631-PA. (266 aa)

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL000584	AAEL801209	Q17NV3	J9HYS2	AAEL000584-PA.	POU domain protein.	0.539
AAEL001104	AAEL013353	Q17M42	Q16JE9	AAEL001104-PA.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.653
AAEL001190	AAEL003109	Q17M30	Q17GF2	AAEL001190-PA.	AAEL003109-PA.	0.513
AAEL001428	AAEL010210	Q17LB7	Q16TK9	Transcription factor Hairy, putative.	Neurogenic locus notch (notch).	0.464
AAEL001473	AAEL001476	Q17L16	Q17L41	AAEL001473-PA.	AAEL001476-PA.	0.521
AAEL001476	AAEL001473	Q17L41	Q17L16	AAEL001476-PA.	AAEL001473-PA.	0.521
AAEL001476	AAEL002885	Q17L41	Q17GR4	AAEL001476-PA.	Protein kinase c zeta and iota isoform; Belongs to the protein kinase superfamily.	0.769
AAEL001476	AAEL008234	Q17L41	Q16ZD5	AAEL001476-PA.	AAEL008234-PA.	0.684
AAEL001476	AAEL010210	Q17L41	Q16TK9	AAEL001476-PA.	Neurogenic locus notch (notch).	0.973
AAEL001476	AAEL010352	Q17L41	Q16T71	AAEL001476-PA.	AAEL010352-PA.	0.741
AAEL001682	AAEL003682	Q17KI6	Q17ET4	AAEL001682-PA.	AAEL003682-PA.	0.876
AAEL001682	AAEL013068	Q17KI6	Q16K96	AAEL001682-PA.	Serine/threonine-protein phosphatase.	0.578
AAEL001682	AAEL013390	Q17KI6	Q16JA1	AAEL001682-PA.	AAEL013390-PA.	0.849
AAEL001711	AAEL008696	Q17KD7	Q16Y16	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.709
AAEL001711	AAEL009737	Q17KD7	Q16V00	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	AAEL009737-PA.	0.519
AAEL001727	AAEL008696	Q17KD6	Q16Y16	AAEL001727-PA.	Mothers against decapentaplegic homolog.	0.589
AAEL001727	AAEL009737	Q17KD6	Q16V00	AAEL001727-PA.	AAEL009737-PA.	0.519
AAEL002129	AAEL003109	Q17J82	Q17GF2	AAEL002129-PA.	AAEL003109-PA.	0.449
AAEL002346	AAEL002653	Q17IK8	Q17HL9	AAEL002346-PB.	AAEL002653-PA.	0.824
AAEL002346	AAEL003063	Q17IK8	Q0IG92	AAEL002346-PB.	AAEL003063-PA; Belongs to the semaphorin family.	0.946