36 items (Aedes aegypti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AAEL013617	AAEL013617-PA. (465 aa)
	AAEL013596	Phosphatidylinositol 3-kinase regulatory subunit. (568 aa)
	AAEL000450	AAEL000450-PA. (944 aa)
	AAEL013539	AAEL013539-PA. (400 aa)
	AAEL012752	Tyrosine-protein kinase. (465 aa)
	AAEL012473	AAEL012473-PB. (771 aa)
	AAEL010041	AAEL010041-PA. (341 aa)
	AAEL009739	AAEL009739-PA. (276 aa)
	STAT1	Signal transducer and activator of transcription. (760 aa)
	AAEL008777	AAEL008777-PA. (1578 aa)
	AAEL008739	AAEL008739-PA. (422 aa)
	AAEL008732	Tyrosine-protein kinase. (939 aa)
	AAEL008554	AAEL008554-PA. (111 aa)
	AAEL008552	AAEL008552-PA. (93 aa)
	AAEL008528	AAEL008528-PA. (511 aa)
	AAEL006936	AAEL006936-PA. (186 aa)
	AAEL006949	AAEL006949-PA. (399 aa)
	AAEL006956	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1779 aa)
	AAEL005347	AAEL005347-PA. (910 aa)
	AAEL006523	AAEL006523-PA. (278 aa)
	AAEL004961	AAEL004961-PA. (1044 aa)
	AAEL004898	AAEL004898-PA. (316 aa)
	AAEL004592	Tyrosine-protein kinase. (540 aa)
	AAEL004431	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1210 aa)
	AAEL001017	Tyrosine-protein kinase. (747 aa)
	AAEL001142	AAEL001142-PA. (1563 aa)
	AAEL004326	AAEL004326-PA. (334 aa)
	AAEL002471	Tyrosine-protein kinase. (392 aa)
	AAEL004125	Signal transduction protein lnk-realted. (564 aa)
	AAEL002862	AAEL002862-PA. (531 aa)
	AAEL002553	AAEL002553-PA. (264 aa)
	AAEL000255	AAEL000255-PA. (312 aa)
	AAEL003937	Tyrosine-protein kinase. (628 aa)
	AAEL000393	Suppressors of cytokine signalling. (198 aa)
	AAEL014512	Tyrosine-protein kinase. (1153 aa)
	AAEL013786	Growth factor receptor-bound protein. (182 aa)

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL000255	AAEL000393	Q17PR7	Q0IGF1	AAEL000255-PA.	Suppressors of cytokine signalling.	0.475
AAEL000255	STAT1	Q17PR7	Q16V47	AAEL000255-PA.	Signal transducer and activator of transcription.	0.405
AAEL000393	AAEL000255	Q0IGF1	Q17PR7	Suppressors of cytokine signalling.	AAEL000255-PA.	0.475
AAEL000393	STAT1	Q0IGF1	Q16V47	Suppressors of cytokine signalling.	Signal transducer and activator of transcription.	0.739
AAEL000450	AAEL006523	Q17P86	Q0IF64	AAEL000450-PA.	AAEL006523-PA.	0.460
AAEL000450	AAEL013786	Q17P86	Q16GF8	AAEL000450-PA.	Growth factor receptor-bound protein.	0.428
AAEL001017	AAEL002471	Q17MF5	Q17I40	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.874
AAEL001017	AAEL004125	Q17MF5	Q17DJ2	Tyrosine-protein kinase.	Signal transduction protein lnk-realted.	0.444
AAEL001017	AAEL004431	Q17MF5	Q17CT3	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.645
AAEL001017	AAEL004592	Q17MF5	Q17CE8	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.880
AAEL001017	AAEL006523	Q17MF5	Q0IF64	Tyrosine-protein kinase.	AAEL006523-PA.	0.642
AAEL001017	AAEL008528	Q17MF5	Q16YG8	Tyrosine-protein kinase.	AAEL008528-PA.	0.565
AAEL001017	AAEL008554	Q17MF5	Q16YG3	Tyrosine-protein kinase.	AAEL008554-PA.	0.565
AAEL001017	AAEL008739	Q17MF5	Q16XW4	Tyrosine-protein kinase.	AAEL008739-PA.	0.836
AAEL001017	AAEL009739	Q17MF5	Q16UZ9	Tyrosine-protein kinase.	AAEL009739-PA.	0.579
AAEL001017	AAEL012473	Q17MF5	Q16LZ9	Tyrosine-protein kinase.	AAEL012473-PB.	0.568
AAEL001017	AAEL013539	Q17MF5	Q16IU8	Tyrosine-protein kinase.	AAEL013539-PA.	0.557
AAEL001017	AAEL013596	Q17MF5	Q16IP4	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit.	0.479
AAEL001017	AAEL013786	Q17MF5	Q16GF8	Tyrosine-protein kinase.	Growth factor receptor-bound protein.	0.690
AAEL001017	AAEL014512	Q17MF5	Q16G61	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.552