(12 nodes) Apoptotic factor-mediated response network (Aedes aegypti)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	AAEL011830	Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (243 aa)
	AAEL011012	AAEL011012-PA; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (368 aa)
	IAP2	AAEL006633-PA. (523 aa)
	CASPL1	Caspase (long); Belongs to the peptidase C14A family. (491 aa)
	ARK	Apaf-1 Related Killer. (1399 aa)
	AAEL015296	AAEL015296-PA; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
	AAEL004457	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	IAP1	Inhibitor of Apoptosis (IAP) containing Baculoviral IAP Repeat(s) (BIR domains). (378 aa)
	AAEL003394	AAEL003394-PA. (324 aa)
	AAEL005493	AAEL005493-PA; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (400 aa)
	AAEL014152	AAEL014152-PA. (365 aa)
	CASPS7	Caspase (short); Belongs to the peptidase C14A family. (180 aa)

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL003394	AAEL004457	Q17FM6	Q1HRI9	AAEL003394-PA.	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.400
AAEL003394	ARK	Q17FM6	Q17MT6	AAEL003394-PA.	Apaf-1 Related Killer.	0.684
AAEL004457	AAEL003394	Q1HRI9	Q17FM6	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	AAEL003394-PA.	0.400
AAEL004457	AAEL011830	Q1HRI9	Q16NX0	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	0.553
AAEL004457	AAEL014152	Q1HRI9	Q16H60	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	AAEL014152-PA.	0.541
AAEL004457	ARK	Q1HRI9	Q17MT6	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Apaf-1 Related Killer.	0.984
AAEL004457	CASPL1	Q1HRI9	Q16H55	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase (long); Belongs to the peptidase C14A family.	0.815
AAEL004457	CASPS7	Q1HRI9	Q16MZ1	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Caspase (short); Belongs to the peptidase C14A family.	0.514
AAEL004457	IAP1	Q1HRI9	Q16WV1	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Inhibitor of Apoptosis (IAP) containing Baculoviral IAP Repeat(s) (BIR domains).	0.524
AAEL004457	IAP2	Q1HRI9	Q175J8	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	AAEL006633-PA.	0.524
AAEL005493	IAP1	Q179W2	Q16WV1	AAEL005493-PA; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Inhibitor of Apoptosis (IAP) containing Baculoviral IAP Repeat(s) (BIR domains).	0.445
AAEL005493	IAP2	Q179W2	Q175J8	AAEL005493-PA; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	AAEL006633-PA.	0.445
AAEL011012	IAP1	Q16RA7	Q16WV1	AAEL011012-PA; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Inhibitor of Apoptosis (IAP) containing Baculoviral IAP Repeat(s) (BIR domains).	0.445
AAEL011012	IAP2	Q16RA7	Q175J8	AAEL011012-PA; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	AAEL006633-PA.	0.942
AAEL011830	AAEL004457	Q16NX0	Q1HRI9	Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.553
AAEL011830	ARK	Q16NX0	Q17MT6	Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	Apaf-1 Related Killer.	0.475
AAEL014152	AAEL004457	Q16H60	Q1HRI9	AAEL014152-PA.	Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.541
AAEL014152	ARK	Q16H60	Q17MT6	AAEL014152-PA.	Apaf-1 Related Killer.	0.717
AAEL014152	IAP1	Q16H60	Q16WV1	AAEL014152-PA.	Inhibitor of Apoptosis (IAP) containing Baculoviral IAP Repeat(s) (BIR domains).	0.440
AAEL014152	IAP2	Q16H60	Q175J8	AAEL014152-PA.	AAEL006633-PA.	0.524