(44 nodes) RHOQ GTPase cycle network (Aedes aegypti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AAEL009958	AAEL009958-PA. (687 aa)
	AAEL014868	AAEL014868-PA. (1014 aa)
	AAEL015082	AAEL015082-PA. (608 aa)
	AAEL007429	AAEL007429-PA. (563 aa)
	AAEL009157	RHO GTPase activator, putative. (1543 aa)
	AAEL014485	AAEL014485-PA. (1258 aa)
	AAEL014307	AAEL014307-PA. (595 aa)
	AAEL014012	Membrane-associated guanylate kinase (maguk); Belongs to the MAGUK family. (770 aa)
	AAEL014013	AAEL014013-PA. (204 aa)
	AAEL013729	Myotonin-protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1608 aa)
	AAEL013571	AAEL013571-PA. (114 aa)
	AAEL013280	Rho guanine exchange factor. (977 aa)
	AAEL012699	AAEL012699-PA. (1257 aa)
	AAEL012283	AAEL012283-PA. (927 aa)
	AAEL011599	AAEL011599-PA. (347 aa)
	AAEL011500	Cdc42 protein, putative. (187 aa)
	AAEL011338	AAEL011338-PA. (341 aa)
	AAEL011253	AAEL011253-PA. (1796 aa)
	AAEL010738	Anion exchange protein. (1213 aa)
	AAEL010294	AAEL010294-PA; Belongs to the MAGUK family. (558 aa)
	AAEL009085	AAEL009085-PA. (491 aa)
	AAEL007931	AAEL007931-PA. (537 aa)
	AAEL007240	Cdc42 GTPase-activating protein. (2080 aa)
	AAEL006878	AAEL006878-PA. (71 aa)
	AAEL006786	AAEL006786-PA. (186 aa)
	AAEL006801	Vang-like protein. (562 aa)
	AAEL005958	AAEL005958-PA. (393 aa)
	AAEL004559	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (213 aa)
	AAEL003503	AAEL003503-PA. (208 aa)
	AAEL003220	AAEL003220-PA. (1572 aa)
	AAEL003162	AAEL003162-PA. (891 aa)
	arm	Armadillo segment polarity protein; May associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis (By similarity). Belongs to the beta-catenin family. (832 aa)
	AAEL002336	LAP4 protein (Scribble protein) (Smell-impaired protein). (626 aa)
	AAEL002340	AAEL002340-PA. (1063 aa)
	AAEL002352	AAEL002352-PA. (357 aa)
	AAEL001473	AAEL001473-PA. (1069 aa)
	AAEL001244	AAEL001244-PA. (1450 aa)
	AAEL001205	AAEL001205-PA. (907 aa)
	AAEL000719	AAEL000719-PA. (621 aa)
	AAEL000620	AAEL000620-PA. (187 aa)
	AAEL000624	AAEL000624-PA. (752 aa)
	AAEL000562	AAEL000562-PA. (180 aa)
	AAEL000489	Non-specific serine/threonine protein kinase. (522 aa)
	AAEL015459	AAEL015459-PA. (295 aa)

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL000489	AAEL000719	Q17P09	Q17NI1	Non-specific serine/threonine protein kinase.	AAEL000719-PA.	0.850
AAEL000489	AAEL006786	Q17P09	Q174R0	Non-specific serine/threonine protein kinase.	AAEL006786-PA.	0.861
AAEL000489	AAEL006801	Q17P09	Q174T9	Non-specific serine/threonine protein kinase.	Vang-like protein.	0.423
AAEL000489	AAEL009085	Q17P09	Q16WV5	Non-specific serine/threonine protein kinase.	AAEL009085-PA.	0.425
AAEL000489	AAEL009958	Q17P09	Q16UB2	Non-specific serine/threonine protein kinase.	AAEL009958-PA.	0.694
AAEL000489	AAEL011500	Q17P09	Q16PW1	Non-specific serine/threonine protein kinase.	Cdc42 protein, putative.	0.676
AAEL000489	arm	Q17P09	Q17GS9	Non-specific serine/threonine protein kinase.	Armadillo segment polarity protein; May associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis (By similarity). Belongs to the beta-catenin family.	0.440
AAEL000620	AAEL000624	Q17NP7	Q17NP8	AAEL000620-PA.	AAEL000624-PA.	0.898
AAEL000624	AAEL000620	Q17NP8	Q17NP7	AAEL000624-PA.	AAEL000620-PA.	0.898
AAEL000719	AAEL000489	Q17NI1	Q17P09	AAEL000719-PA.	Non-specific serine/threonine protein kinase.	0.850
AAEL000719	AAEL001205	Q17NI1	Q17LW9	AAEL000719-PA.	AAEL001205-PA.	0.587
AAEL000719	AAEL001473	Q17NI1	Q17L16	AAEL000719-PA.	AAEL001473-PA.	0.429
AAEL000719	AAEL002336	Q17NI1	Q17IJ6	AAEL000719-PA.	LAP4 protein (Scribble protein) (Smell-impaired protein).	0.481
AAEL000719	AAEL006786	Q17NI1	Q174R0	AAEL000719-PA.	AAEL006786-PA.	0.586
AAEL000719	AAEL006801	Q17NI1	Q174T9	AAEL000719-PA.	Vang-like protein.	0.596
AAEL000719	AAEL007429	Q17NI1	Q0IF10	AAEL000719-PA.	AAEL007429-PA.	0.431
AAEL000719	AAEL007931	Q17NI1	Q170F5	AAEL000719-PA.	AAEL007931-PA.	0.734
AAEL000719	AAEL009085	Q17NI1	Q16WV5	AAEL000719-PA.	AAEL009085-PA.	0.590
AAEL000719	AAEL009157	Q17NI1	Q0IEN2	AAEL000719-PA.	RHO GTPase activator, putative.	0.455
AAEL000719	AAEL009958	Q17NI1	Q16UB2	AAEL000719-PA.	AAEL009958-PA.	0.983