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AAEL006850 AAEL006850 AAEL000091 AAEL000091 AAEL012584 AAEL012584 AAEL003757 AAEL003757 AAEL015064 AAEL015064 AAEL014913 AAEL014913 AAEL014393 AAEL014393 AAEL013904 AAEL013904 AAEL013139 AAEL013139 AAEL012904 AAEL012904 AAEL012579 AAEL012579 AAEL012576 AAEL012576 AAEL012580 AAEL012580 GSTS1 GSTS1 AAEL011603 AAEL011603 AAEL011495 AAEL011495 AAEL011268 AAEL011268 AAEL011137 AAEL011137 AAEL010641 AAEL010641 AAEL010580 AAEL010580 AAEL010208 AAEL010208 AAEL009732 AAEL009732 AAEL009685 AAEL009685 AAEL009601 AAEL009601 AAEL009462 AAEL009462 AAEL008952 AAEL008952 AAEL008933 AAEL008933 Cdc42 Cdc42 AAEL007858 AAEL007858 AAEL007683 AAEL007683 AAEL006975 AAEL006975 AAEL006928 AAEL006928 AAEL006837 AAEL006837 AAEL006786 AAEL006786 AAEL006684 AAEL006684 AAEL005766 AAEL005766 MNSOD2 MNSOD2 MNSOD1 MNSOD1 AAEL004059 AAEL004059 AAEL003568 AAEL003568 AAEL001853 AAEL001853 AAEL000757 AAEL000757 AAEL000758 AAEL000758 AAEL000542 AAEL000542 AAEL015271 AAEL015271 AAEL012996 AAEL012996 AAEL005270 AAEL005270 PCNA PCNA mAAT mAAT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AAEL0068503-hydroxyisobutyrate dehydrogenase. (284 aa)
AAEL000091AAEL000091-PA. (332 aa)
AAEL012584DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1300 aa)
AAEL003757Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (527 aa)
AAEL015064Small ubiquitin-related modifier. (95 aa)
AAEL014913Pyruvate kinase; Belongs to the pyruvate kinase family. (529 aa)
AAEL014393AAEL014393-PA. (179 aa)
AAEL0139043-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (324 aa)
AAEL013139AAEL013139-PD. (207 aa)
AAEL012904Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (443 aa)
AAEL012579Aspartate aminotransferase. (408 aa)
AAEL012576Pyruvate kinase; Belongs to the pyruvate kinase family. (519 aa)
AAEL012580AAEL012580-PA. (274 aa)
GSTS1Glutathione transferase. (203 aa)
AAEL011603DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (856 aa)
AAEL011495AAEL011495-PA. (762 aa)
AAEL011268AAEL011268-PA. (231 aa)
AAEL011137Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (456 aa)
AAEL010641SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. (642 aa)
AAEL010580AAEL010580-PA. (198 aa)
AAEL0102083-hydroxyisobutyrate dehydrogenase. (243 aa)
AAEL009732AAEL009732-PA. (192 aa)
AAEL009685Oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
AAEL009601AAEL009601-PA. (306 aa)
AAEL009462Hydroxyacylglutathione hydrolase. (263 aa)
AAEL008952AAEL008952-PA. (582 aa)
AAEL0089333-hydroxyisobutyrate dehydrogenase. (339 aa)
Cdc42Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity); Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. (191 aa)
AAEL007858AAEL007858-PA. (583 aa)
AAEL007683DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1021 aa)
AAEL006975Leucine aminopeptidase. (552 aa)
AAEL006928Dihydrolipoyl dehydrogenase. (508 aa)
AAEL0068373-hydroxyisobutyrate dehydrogenase. (283 aa)
AAEL006786AAEL006786-PA. (186 aa)
AAEL006684Putative oxidoreductase GLYR1 homolog; May have oxidoreductase activity. Belongs to the HIBADH-related family. NP60 subfamily. (559 aa)
AAEL005766Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
MNSOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (219 aa)
MNSOD1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (219 aa)
AAEL004059Cystathionine beta-lyase. (438 aa)
AAEL003568AAEL003568-PA. (463 aa)
AAEL001853Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (629 aa)
AAEL000757AAEL000757-PB. (360 aa)
AAEL000758Ubiquitin-activating enzyme E1; Belongs to the ubiquitin-activating E1 family. (1102 aa)
AAEL000542Amine oxidase. (487 aa)
AAEL015271AAEL015271-PA. (195 aa)
AAEL012996Rho GDP dissociation inhibitor. (200 aa)
AAEL005270Farnesoic acid O-methyl transferase-like protein. (144 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
mAATAspartate aminotransferase. (429 aa)
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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