(34 nodes) Endoplasmic reticulum organization network (Anopheles gambiae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q5TV94_ANOGA	AGAP003872-PA. (3145 aa)
	Q5TTG0_ANOGA	Protein jagunal. (197 aa)
	Q5TT42_ANOGA	AGAP003647-PA. (922 aa)
	ASNA_ANOGA	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (337 aa)
	A7US31_ANOGA	AGAP011214-PA. (750 aa)
	A7URV7_ANOGA	AGAP006935-PA. (652 aa)
	Q7QIP7_ANOGA	AGAP007000-PA. (109 aa)
	Q7QHF0_ANOGA	AGAP011162-PA. (1899 aa)
	Q7QF05_ANOGA	Vesicle transport protein SEC20. (235 aa)
	Q7QF73_ANOGA	AGAP000334-PA. (403 aa)
	Q7QFR1_ANOGA	Vesicle-associated membrane protein-associated protein B. (291 aa)
	Q7QH65_ANOGA	AGAP004056-PA. (164 aa)
	Q7QER9_ANOGA	Golgi to ER traffic protein 4 homolog. (326 aa)
	Q7QDS0_ANOGA	Translocating chain-associated membrane protein 2. (374 aa)
	Q7QC06_ANOGA	Ubiquitin-like 4A. (139 aa)
	Q7QA71_ANOGA	Lectin, mannose-binding 2. (335 aa)
	Q7Q9M7_ANOGA	AGAP005150-PA. (136 aa)
	Q7Q8U0_ANOGA	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (172 aa)
	Q7Q7Q1_ANOGA	AGAP004626-PA. (235 aa)
	Q7Q7B2_ANOGA	Lectin, mannose-binding 1. (526 aa)
	Q7Q4A7_ANOGA	Dolichyl-phosphate beta-glucosyltransferase. (327 aa)
	Q7Q3Q4_ANOGA	AGAP007983-PA. (341 aa)
	Q7PZ49_ANOGA	AGAP011730-PA; Belongs to the small GTPase superfamily. Arf family. (179 aa)
	Q7PY59_ANOGA	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (772 aa)
	Q7PXC7_ANOGA	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (521 aa)
	Q7PUS9_ANOGA	AGAP002047-PA. (537 aa)
	Q7PST7_ANOGA	AGAP011346-PA. (228 aa)
	Q7PSF7_ANOGA	AGAP011551-PA. (1280 aa)
	Q7PQL9_ANOGA	GTP-binding protein SAR1; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
	Q7PPP2_ANOGA	AGAP008803-PA. (107 aa)
	Q7PPB7_ANOGA	AGAP005769-PA. (223 aa)
	Q7PJT0_ANOGA	AGAP010214-PA. (259 aa)
	Q7PIQ3_ANOGA	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (804 aa)
	Q5TVA9_ANOGA	Extended synaptotagmin-like protein 2a. (834 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A7US31_ANOGA	Q7PPP2_ANOGA	A7US31	Q7PPP2	AGAP011214-PA.	AGAP008803-PA.	0.983
A7US31_ANOGA	Q7PQL9_ANOGA	A7US31	Q7PQL9	AGAP011214-PA.	GTP-binding protein SAR1; Belongs to the small GTPase superfamily. SAR1 family.	0.921
A7US31_ANOGA	Q7PSF7_ANOGA	A7US31	Q7PSF7	AGAP011214-PA.	AGAP011551-PA.	0.943
A7US31_ANOGA	Q7PY59_ANOGA	A7US31	Q7PY59	AGAP011214-PA.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.988
A7US31_ANOGA	Q7Q7B2_ANOGA	A7US31	Q7Q7B2	AGAP011214-PA.	Lectin, mannose-binding 1.	0.817
A7US31_ANOGA	Q7QA71_ANOGA	A7US31	Q7QA71	AGAP011214-PA.	Lectin, mannose-binding 2.	0.654
ASNA_ANOGA	Q7QC06_ANOGA	Q5TRE7	Q7QC06	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Ubiquitin-like 4A.	0.697
ASNA_ANOGA	Q7QER9_ANOGA	Q5TRE7	Q7QER9	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Golgi to ER traffic protein 4 homolog.	0.993
ASNA_ANOGA	Q7QH65_ANOGA	Q5TRE7	Q7QH65	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	AGAP004056-PA.	0.994
Q5TT42_ANOGA	Q7PST7_ANOGA	Q5TT42	Q7PST7	AGAP003647-PA.	AGAP011346-PA.	0.980
Q5TT42_ANOGA	Q7Q7Q1_ANOGA	Q5TT42	Q7Q7Q1	AGAP003647-PA.	AGAP004626-PA.	0.984
Q5TT42_ANOGA	Q7Q8U0_ANOGA	Q5TT42	Q7Q8U0	AGAP003647-PA.	ER membrane protein complex subunit 4; Belongs to the EMC4 family.	0.996
Q5TVA9_ANOGA	Q7QFR1_ANOGA	Q5TVA9	Q7QFR1	Extended synaptotagmin-like protein 2a.	Vesicle-associated membrane protein-associated protein B.	0.546
Q7PIQ3_ANOGA	Q7QC06_ANOGA	Q7PIQ3	Q7QC06	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	Ubiquitin-like 4A.	0.491
Q7PPP2_ANOGA	A7US31_ANOGA	Q7PPP2	A7US31	AGAP008803-PA.	AGAP011214-PA.	0.983
Q7PPP2_ANOGA	Q7PQL9_ANOGA	Q7PPP2	Q7PQL9	AGAP008803-PA.	GTP-binding protein SAR1; Belongs to the small GTPase superfamily. SAR1 family.	0.889
Q7PPP2_ANOGA	Q7PSF7_ANOGA	Q7PPP2	Q7PSF7	AGAP008803-PA.	AGAP011551-PA.	0.941
Q7PPP2_ANOGA	Q7PY59_ANOGA	Q7PPP2	Q7PY59	AGAP008803-PA.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.998
Q7PPP2_ANOGA	Q7Q7B2_ANOGA	Q7PPP2	Q7Q7B2	AGAP008803-PA.	Lectin, mannose-binding 1.	0.787
Q7PPP2_ANOGA	Q7QA71_ANOGA	Q7PPP2	Q7QA71	AGAP008803-PA.	Lectin, mannose-binding 2.	0.684