8 items (Anopheles gambiae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	F5HIZ2_ANOGA	AGAP013514-PA. (247 aa)
	Q5TVX2_ANOGA	AGAP011091-PA. (107 aa)
	sxl	AGAP003899-PA. (302 aa)
	Q7PMT7_ANOGA	ATP-dependent RNA helicase DDX1. (728 aa)
	Q7PQ20_ANOGA	Polyadenylate-binding protein 2. (221 aa)
	Q7PQL7_ANOGA	AGAP004265-PA. (1226 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (737 aa)
	Q7QH99_ANOGA	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (634 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F5HIZ2_ANOGA	PAN3	F5HIZ2	Q7Q6T6	AGAP013514-PA.	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]	0.691
F5HIZ2_ANOGA	Q7PQ20_ANOGA	F5HIZ2	Q7PQ20	AGAP013514-PA.	Polyadenylate-binding protein 2.	0.513
PAN3	F5HIZ2_ANOGA	Q7Q6T6	F5HIZ2	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]	AGAP013514-PA.	0.691
PAN3	Q5TVX2_ANOGA	Q7Q6T6	Q5TVX2	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]	AGAP011091-PA.	0.691
PAN3	Q7QH99_ANOGA	Q7Q6T6	Q7QH99	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.691
Q5TVX2_ANOGA	PAN3	Q5TVX2	Q7Q6T6	AGAP011091-PA.	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]	0.691
Q5TVX2_ANOGA	Q7PQ20_ANOGA	Q5TVX2	Q7PQ20	AGAP011091-PA.	Polyadenylate-binding protein 2.	0.513
Q7PQ20_ANOGA	F5HIZ2_ANOGA	Q7PQ20	F5HIZ2	Polyadenylate-binding protein 2.	AGAP013514-PA.	0.513
Q7PQ20_ANOGA	Q5TVX2_ANOGA	Q7PQ20	Q5TVX2	Polyadenylate-binding protein 2.	AGAP011091-PA.	0.513
Q7PQ20_ANOGA	Q7PQL7_ANOGA	Q7PQ20	Q7PQL7	Polyadenylate-binding protein 2.	AGAP004265-PA.	0.600
Q7PQ20_ANOGA	Q7QH99_ANOGA	Q7PQ20	Q7QH99	Polyadenylate-binding protein 2.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.513
Q7PQL7_ANOGA	Q7PQ20_ANOGA	Q7PQL7	Q7PQ20	AGAP004265-PA.	Polyadenylate-binding protein 2.	0.600
Q7QH99_ANOGA	PAN3	Q7QH99	Q7Q6T6	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]	0.691
Q7QH99_ANOGA	Q7PQ20_ANOGA	Q7QH99	Q7PQ20	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	Polyadenylate-binding protein 2.	0.513