(87 nodes) Apical plasma membrane network (Anopheles gambiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q7QKM3_ANOGA	Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor protein-1. (633 aa)
	A0NB09_ANOGA	AGAP012716-PA. (166 aa)
	A0NB52_ANOGA	AGAP012478-PA. (177 aa)
	A0NCY1_ANOGA	AGAP003419-PA. (128 aa)
	A0NE37_ANOGA	AGAP008683-PA. (429 aa)
	A0NH37_ANOGA	Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (358 aa)
	A7USM6_ANOGA	AGAP010743-PA. (129 aa)
	A7UTA7_ANOGA	AGAP005222-PA. (286 aa)
	A7UU93_ANOGA	Phospholipase B, plb1. (420 aa)
	A7UV07_ANOGA	AGAP010745-PA. (119 aa)
	A7UV11_ANOGA	AGAP010808-PA. (920 aa)
	A7UVC0_ANOGA	AGAP012405-PA. (478 aa)
	F5HJH6_ANOGA	AGAP013262-PA. (1112 aa)
	F5HK15_ANOGA	AGAP013345-PA. (128 aa)
	GPRMGL4	Chloride channel protein. (1180 aa)
	F5HKU7_ANOGA	AGAP013206-PA. (305 aa)
	Q5TNA8_ANOGA	AGAP008996-PA; Belongs to the peptidase S1 family. (249 aa)
	Q5TNB1_ANOGA	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (1222 aa)
	Q5TND5_ANOGA	AGAP009261-PA. (1481 aa)
	Q5TQJ5_ANOGA	AGAP008245-PA. (674 aa)
	Q5TQZ3_ANOGA	Phospholipase b, plb1. (418 aa)
	Q5TRU2_ANOGA	Phospholipase b, plb1. (412 aa)
	Q7PCR1_ANOGA	AGAP010744-PA. (103 aa)
	Q7PI39_ANOGA	Phospholipase b, plb1. (334 aa)
	Q7PMJ7_ANOGA	AGAP010746-PA. (252 aa)
	Q7PMK0_ANOGA	AGAP010767-PA. (1932 aa)
	Q7PMQ5_ANOGA	AGAP010325-PA; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	Q7PNK0_ANOGA	Partitioning defective protein 3. (1862 aa)
	Q7PPB2_ANOGA	AGAP006256-PA. (1821 aa)
	EGFR	Receptor protein-tyrosine kinase. (1429 aa)
	GPRSTN	AGAP004850-PA; Belongs to the G-protein coupled receptor 2 family. (3543 aa)
	Q7PQS3_ANOGA	AGAP003211-PA. (637 aa)
	Q7PQW5_ANOGA	Stardust, isoform B; Belongs to the MAGUK family. (1567 aa)
	Q7PR41_ANOGA	AGAP002310-PA. (1762 aa)
	Q7PR92_ANOGA	AGAP002579-PA. (1107 aa)
	Q7PR98_ANOGA	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (523 aa)
	Q7PRJ8_ANOGA	AGAP010346-PA. (584 aa)
	Q7PRK4_ANOGA	AGAP010742-PA. (1195 aa)
	Q7PST1_ANOGA	AGAP011178-PA. (398 aa)
	Q7PSV8_ANOGA	AGAP001015-PA. (2800 aa)
	Q7PSY9_ANOGA	AGAP005288-PA. (3164 aa)
	Q7PT34_ANOGA	AGAP007478-PA. (1149 aa)
	Q7PUL5_ANOGA	AGAP001637-PA. (205 aa)
	Q7PV46_ANOGA	AGAP012008-PA. (304 aa)
	Q7PVZ6_ANOGA	AGAP009136-PA. (653 aa)
	Q7PW08_ANOGA	AGAP009126-PA. (1437 aa)
	Q7PWD5_ANOGA	AGAP009005-PA. (472 aa)
	Q7PWV0_ANOGA	AGAP008843-PA; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa)
	Q7PY10_ANOGA	Exocyst complex component 4. (1076 aa)
	Q7PY93_ANOGA	AGAP001800-PA. (480 aa)
	Q7PYI3_ANOGA	TBC1 domain family, member 10A. (397 aa)
	Q7PYS7_ANOGA	AGAP002089-PA. (732 aa)
	Q7PZM8_ANOGA	AGAP011988-PA. (80 aa)
	Q7PZN0_ANOGA	AGAP011993-PA. (135 aa)
	Q7Q1Z7_ANOGA	AGAP010748-PA. (152 aa)
	Q7Q2B1_ANOGA	Battenin. (448 aa)
	Q7Q462_ANOGA	AGAP008237-PA. (250 aa)
	Q7Q464_ANOGA	AGAP008243-PA. (751 aa)
	Q7Q515_ANOGA	Spectrin alpha. (2417 aa)
	Q7Q5Y1_ANOGA	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (289 aa)
	Q7Q6C8_ANOGA	Solute carrier family 30 (zinc transporter), member 1. (454 aa)
	Q7Q6K2_ANOGA	AGAP005799-PA; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (607 aa)
	Q7Q7K2_ANOGA	AGAP011511-PA. (374 aa)
	Q7Q7L5_ANOGA	AGAP012464-PA. (426 aa)
	Q7Q8V8_ANOGA	AGAP010539-PA. (841 aa)
	Q7Q8X8_ANOGA	Partitioning defective protein 6. (314 aa)
	Q7QA48_ANOGA	AGAP004440-PA. (4202 aa)
	Q7QAJ0_ANOGA	AGAP003680-PA. (777 aa)
	Q7QB67_ANOGA	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1370 aa)
	Q7QBU9_ANOGA	AGAP002322-PA. (559 aa)
	Q7QCI0_ANOGA	ATP-binding cassette transporter (ABC transporter) family H member 1. (776 aa)
	Q7QCJ8_ANOGA	AGAP002663-PA. (370 aa)
	Q7QCP4_ANOGA	AGAP002739-PA. (3538 aa)
	Q7QCU0_ANOGA	Neural cell adhesion molecule. (855 aa)
	Q7QD96_ANOGA	AGAP003012-PA. (695 aa)
	Q7QDA4_ANOGA	Ras-related protein Rab-35. (202 aa)
	Q7QDY9_ANOGA	AGAP010740-PA. (144 aa)
	Q7QE77_ANOGA	AGAP000786-PA. (655 aa)
	KIBRLG	WW domain-containing protein. (1013 aa)
	Q7QEY7_ANOGA	AGAP000217-PA. (856 aa)
	Q7QEY8_ANOGA	AGAP000218-PA. (884 aa)
	Q7QF51_ANOGA	AGAP000307-PA; Belongs to the integrin alpha chain family. (1177 aa)
	Q7QFS2_ANOGA	AGAP003873-PA. (2118 aa)
	Q7QGT1_ANOGA	AGAP010881-PA. (634 aa)
	Q7QIW9_ANOGA	AGAP007108-PA. (879 aa)
	Q7QJI4_ANOGA	AGAP007532-PA. (965 aa)
	Q7QKK7_ANOGA	AGAP003261-PA. (1737 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0NB09_ANOGA	A7USM6_ANOGA	A0NB09	A7USM6	AGAP012716-PA.	AGAP010743-PA.	0.725
A0NB09_ANOGA	Q7QDY9_ANOGA	A0NB09	Q7QDY9	AGAP012716-PA.	AGAP010740-PA.	0.538
A0NB09_ANOGA	Q7QEY7_ANOGA	A0NB09	Q7QEY7	AGAP012716-PA.	AGAP000217-PA.	0.577
A0NB09_ANOGA	Q7QEY8_ANOGA	A0NB09	Q7QEY8	AGAP012716-PA.	AGAP000218-PA.	0.577
A0NB52_ANOGA	Q7Q464_ANOGA	A0NB52	Q7Q464	AGAP012478-PA.	AGAP008243-PA.	0.601
A7USM6_ANOGA	A0NB09_ANOGA	A7USM6	A0NB09	AGAP010743-PA.	AGAP012716-PA.	0.725
A7USM6_ANOGA	Q7PMJ7_ANOGA	A7USM6	Q7PMJ7	AGAP010743-PA.	AGAP010746-PA.	0.754
A7USM6_ANOGA	Q7QEY7_ANOGA	A7USM6	Q7QEY7	AGAP010743-PA.	AGAP000217-PA.	0.577
A7USM6_ANOGA	Q7QEY8_ANOGA	A7USM6	Q7QEY8	AGAP010743-PA.	AGAP000218-PA.	0.577
A7UTA7_ANOGA	Q7Q7L5_ANOGA	A7UTA7	Q7Q7L5	AGAP005222-PA.	AGAP012464-PA.	0.443
A7UV07_ANOGA	Q7QEY7_ANOGA	A7UV07	Q7QEY7	AGAP010745-PA.	AGAP000217-PA.	0.577
A7UV07_ANOGA	Q7QEY8_ANOGA	A7UV07	Q7QEY8	AGAP010745-PA.	AGAP000218-PA.	0.577
EGFR	KIBRLG	Q7PPN5	Q7QEI4	Receptor protein-tyrosine kinase.	WW domain-containing protein.	0.538
EGFR	Q7PMK0_ANOGA	Q7PPN5	Q7PMK0	Receptor protein-tyrosine kinase.	AGAP010767-PA.	0.665
EGFR	Q7PR98_ANOGA	Q7PPN5	Q7PR98	Receptor protein-tyrosine kinase.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.510
EGFR	Q7PSV8_ANOGA	Q7PPN5	Q7PSV8	Receptor protein-tyrosine kinase.	AGAP001015-PA.	0.464
EGFR	Q7PVZ6_ANOGA	Q7PPN5	Q7PVZ6	Receptor protein-tyrosine kinase.	AGAP009136-PA.	0.969
EGFR	Q7PY93_ANOGA	Q7PPN5	Q7PY93	Receptor protein-tyrosine kinase.	AGAP001800-PA.	0.669
F5HKU7_ANOGA	Q7PR92_ANOGA	F5HKU7	Q7PR92	AGAP013206-PA.	AGAP002579-PA.	0.416
KIBRLG	EGFR	Q7QEI4	Q7PPN5	WW domain-containing protein.	Receptor protein-tyrosine kinase.	0.538