(20 nodes) Embryonic hemopoiesis network (Anopheles gambiae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	Q7PNL6_ANOGA	AGAP005445-PA. (192 aa)
	A7USU7_ANOGA	AGAP002546-PA. (238 aa)
	A7UT88_ANOGA	Ras homolog gene family, member A. (207 aa)
	F5HKZ0_ANOGA	Ras-related C3 botulinum toxin substrate 1 precursor. (194 aa)
	F5HLZ2_ANOGA	Fascin. (511 aa)
	F5HMC8_ANOGA	Ras-related protein Rap-1A. (184 aa)
	Cdc42	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity); Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. (191 aa)
	Q380U3_ANOGA	Ras-related C3 botulinum toxin substrate 1. (195 aa)
	Q5TND5_ANOGA	AGAP009261-PA. (1481 aa)
	Q5TQ16_ANOGA	AGAP007782-PA. (165 aa)
	Q5TQ17_ANOGA	AGAP007783-PA. (480 aa)
	Q5TVE6_ANOGA	AGAP009549-PA; Belongs to the PDGF/VEGF growth factor family. (199 aa)
	Q7PSV8_ANOGA	AGAP001015-PA. (2800 aa)
	Q7Q5P9_ANOGA	Cell division control protein 42. (190 aa)
	Q7Q6Z9_ANOGA	Pre-rRNA-processing protein TSR4. (351 aa)
	Q7Q840_ANOGA	Receptor protein-tyrosine kinase. (1247 aa)
	INTB	Integrin beta; Belongs to the integrin beta chain family. (837 aa)
	Q7QEJ7_ANOGA	AGAP000018-PA; Belongs to the PI3/PI4-kinase family. (1133 aa)
	Q7QEK5_ANOGA	AGAP000032-PA; Belongs to the integrin alpha chain family. (1540 aa)
	Q7QJR3_ANOGA	AGAP007623-PA. (1462 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A7UT88_ANOGA	Cdc42	A7UT88	Q17031	Ras homolog gene family, member A.	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity); Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	0.616
A7UT88_ANOGA	F5HKZ0_ANOGA	A7UT88	F5HKZ0	Ras homolog gene family, member A.	Ras-related C3 botulinum toxin substrate 1 precursor.	0.621
A7UT88_ANOGA	F5HMC8_ANOGA	A7UT88	F5HMC8	Ras homolog gene family, member A.	Ras-related protein Rap-1A.	0.427
A7UT88_ANOGA	Q380U3_ANOGA	A7UT88	Q380U3	Ras homolog gene family, member A.	Ras-related C3 botulinum toxin substrate 1.	0.617
A7UT88_ANOGA	Q7PNL6_ANOGA	A7UT88	Q7PNL6	Ras homolog gene family, member A.	AGAP005445-PA.	0.617
A7UT88_ANOGA	Q7Q5P9_ANOGA	A7UT88	Q7Q5P9	Ras homolog gene family, member A.	Cell division control protein 42.	0.631
A7UT88_ANOGA	Q7QEJ7_ANOGA	A7UT88	Q7QEJ7	Ras homolog gene family, member A.	AGAP000018-PA; Belongs to the PI3/PI4-kinase family.	0.435
Cdc42	A7UT88_ANOGA	Q17031	A7UT88	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity); Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Ras homolog gene family, member A.	0.616
Cdc42	Q7Q5P9_ANOGA	Q17031	Q7Q5P9	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity); Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	Cell division control protein 42.	0.910
Cdc42	Q7QEJ7_ANOGA	Q17031	Q7QEJ7	Cdc42 homolog; Regulates mbt kinase activity and is also required to recruit mbt to adherens junctions. Together with mbt, regulates photoreceptor cell morphogenesis (By similarity); Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.	AGAP000018-PA; Belongs to the PI3/PI4-kinase family.	0.433
F5HKZ0_ANOGA	A7UT88_ANOGA	F5HKZ0	A7UT88	Ras-related C3 botulinum toxin substrate 1 precursor.	Ras homolog gene family, member A.	0.621
F5HKZ0_ANOGA	Q380U3_ANOGA	F5HKZ0	Q380U3	Ras-related C3 botulinum toxin substrate 1 precursor.	Ras-related C3 botulinum toxin substrate 1.	0.912
F5HKZ0_ANOGA	Q7PNL6_ANOGA	F5HKZ0	Q7PNL6	Ras-related C3 botulinum toxin substrate 1 precursor.	AGAP005445-PA.	0.913
F5HKZ0_ANOGA	Q7QEJ7_ANOGA	F5HKZ0	Q7QEJ7	Ras-related C3 botulinum toxin substrate 1 precursor.	AGAP000018-PA; Belongs to the PI3/PI4-kinase family.	0.433
F5HMC8_ANOGA	A7UT88_ANOGA	F5HMC8	A7UT88	Ras-related protein Rap-1A.	Ras homolog gene family, member A.	0.427
F5HMC8_ANOGA	INTB	F5HMC8	Q7QE55	Ras-related protein Rap-1A.	Integrin beta; Belongs to the integrin beta chain family.	0.517
F5HMC8_ANOGA	Q5TND5_ANOGA	F5HMC8	Q5TND5	Ras-related protein Rap-1A.	AGAP009261-PA.	0.842
F5HMC8_ANOGA	Q7QEJ7_ANOGA	F5HMC8	Q7QEJ7	Ras-related protein Rap-1A.	AGAP000018-PA; Belongs to the PI3/PI4-kinase family.	0.429
INTB	F5HMC8_ANOGA	Q7QE55	F5HMC8	Integrin beta; Belongs to the integrin beta chain family.	Ras-related protein Rap-1A.	0.517
INTB	Q7PSV8_ANOGA	Q7QE55	Q7PSV8	Integrin beta; Belongs to the integrin beta chain family.	AGAP001015-PA.	0.541