(19 nodes) pre-mRNA binding network (Anopheles gambiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q7QFV6_ANOGA	AGAP003817-PA. (910 aa)
	F5HJ86_ANOGA	AGAP013051-PA. (420 aa)
	A7UTY6_ANOGA	AGAP005940-PA. (879 aa)
	A0A1W5C940	AGAP011241-PA. (228 aa)
	A0A1W5C937	AGAP011240-PA. (234 aa)
	F5HL36_ANOGA	AGAP012972-PA. (305 aa)
	F5HL37_ANOGA	AGAP013023-PB. (305 aa)
	Q7PX44_ANOGA	AGAP001203-PA. (168 aa)
	AGAP001584	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (152 aa)
	Q7PYY3_ANOGA	U1 small nuclear ribonucleoprotein A. (216 aa)
	Q7Q0R8_ANOGA	AGAP010194-PA. (505 aa)
	Q7Q2R2_ANOGA	AGAP004776-PA. (594 aa)
	Q7Q9Z7_ANOGA	Pre-mRNA-splicing factor RBM22/SLT11. (441 aa)
	Q7QD06_ANOGA	AGAP002896-PA. (537 aa)
	Q7QD20_ANOGA	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (446 aa)
	Q7QD49_ANOGA	Splicing factor U2AF 35 kDa subunit. (251 aa)
	Q7QII3_ANOGA	Pre-mRNA-processing factor 8. (2388 aa)
	Q7QEL7_ANOGA	AGAP000049-PA. (783 aa)
	Q7QID9_ANOGA	Transformer-2 protein. (271 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1W5C937	A0A1W5C940	A0A1W5C937	A0A1W5C940	AGAP011240-PA.	AGAP011241-PA.	0.898
A0A1W5C937	Q7Q0R8_ANOGA	A0A1W5C937	Q7Q0R8	AGAP011240-PA.	AGAP010194-PA.	0.731
A0A1W5C937	Q7Q2R2_ANOGA	A0A1W5C937	Q7Q2R2	AGAP011240-PA.	AGAP004776-PA.	0.515
A0A1W5C937	Q7QD49_ANOGA	A0A1W5C937	Q7QD49	AGAP011240-PA.	Splicing factor U2AF 35 kDa subunit.	0.731
A0A1W5C937	Q7QEL7_ANOGA	A0A1W5C937	Q7QEL7	AGAP011240-PA.	AGAP000049-PA.	0.651
A0A1W5C940	A0A1W5C937	A0A1W5C940	A0A1W5C937	AGAP011241-PA.	AGAP011240-PA.	0.898
A0A1W5C940	Q7Q0R8_ANOGA	A0A1W5C940	Q7Q0R8	AGAP011241-PA.	AGAP010194-PA.	0.731
A0A1W5C940	Q7Q2R2_ANOGA	A0A1W5C940	Q7Q2R2	AGAP011241-PA.	AGAP004776-PA.	0.515
A0A1W5C940	Q7QD49_ANOGA	A0A1W5C940	Q7QD49	AGAP011241-PA.	Splicing factor U2AF 35 kDa subunit.	0.731
A0A1W5C940	Q7QEL7_ANOGA	A0A1W5C940	Q7QEL7	AGAP011241-PA.	AGAP000049-PA.	0.651
A7UTY6_ANOGA	Q7QFV6_ANOGA	A7UTY6	Q7QFV6	AGAP005940-PA.	AGAP003817-PA.	0.427
AGAP001584	Q7PYY3_ANOGA	Q7PXU6	Q7PYY3	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	U1 small nuclear ribonucleoprotein A.	0.996
AGAP001584	Q7Q2R2_ANOGA	Q7PXU6	Q7Q2R2	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	AGAP004776-PA.	0.455
AGAP001584	Q7QD20_ANOGA	Q7PXU6	Q7QD20	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.865
AGAP001584	Q7QEL7_ANOGA	Q7PXU6	Q7QEL7	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	AGAP000049-PA.	0.708
AGAP001584	Q7QII3_ANOGA	Q7PXU6	Q7QII3	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.	Pre-mRNA-processing factor 8.	0.682
F5HJ86_ANOGA	Q7PYY3_ANOGA	F5HJ86	Q7PYY3	AGAP013051-PA.	U1 small nuclear ribonucleoprotein A.	0.504
F5HJ86_ANOGA	Q7QD20_ANOGA	F5HJ86	Q7QD20	AGAP013051-PA.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.439
F5HJ86_ANOGA	Q7QID9_ANOGA	F5HJ86	Q7QID9	AGAP013051-PA.	Transformer-2 protein.	0.914
F5HL36_ANOGA	F5HL37_ANOGA	F5HL36	F5HL37	AGAP012972-PA.	AGAP013023-PB.	0.543