(27 nodes) Cortical actin cytoskeleton network (Anopheles gambiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F5HLS9_ANOGA	Rho GTPase-activating protein 26. (589 aa)
	A0A1W5C968	AGAP009938-PA. (231 aa)
	A0A1W5C970	AGAP009937-PA. (1520 aa)
	A0NB52_ANOGA	AGAP012478-PA. (177 aa)
	A0NHA1_ANOGA	AGAP001934-PA. (300 aa)
	A7USX7_ANOGA	AGAP003149-PA. (294 aa)
	A7UVC9_ANOGA	AGAP012240-PA. (412 aa)
	F5HIS0_ANOGA	AGAP002274-PB. (2799 aa)
	F5HIS1_ANOGA	AGAP002272-PB. (2550 aa)
	Q5TP19_ANOGA	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	Q5TQJ5_ANOGA	AGAP008245-PA. (674 aa)
	Q5TRW2_ANOGA	AGAP004625-PA. (525 aa)
	Actn	Alpha-actinin, sarcomeric; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity); Belongs to the alpha-actinin family. (922 aa)
	Q7PMK0_ANOGA	AGAP010767-PA. (1932 aa)
	Q7PQ74_ANOGA	Lethal giant larvae. (1247 aa)
	Q7PRC8_ANOGA	AGAP002509-PA. (603 aa)
	Q7PRK2_ANOGA	AGAP010715-PA. (1350 aa)
	Q7PSH4_ANOGA	Spectrin beta chain; Belongs to the spectrin family. (2301 aa)
	Q7PVI9_ANOGA	AGAP009264-PA. (369 aa)
	Q7PYF6_ANOGA	AGAP001916-PA. (1794 aa)
	GPRNNB2	AGAP009661-PA. (412 aa)
	Q7Q4S7_ANOGA	Coactosin-like protein. (163 aa)
	Q7Q515_ANOGA	Spectrin alpha. (2417 aa)
	Q7Q6L0_ANOGA	AGAP005783-PA. (2171 aa)
	Q7QA48_ANOGA	AGAP004440-PA. (4202 aa)
	Q7QBJ5_ANOGA	LanC-like protein 3 homolog. (418 aa)
	Q7QIK8_ANOGA	Citron Rho-interacting kinase. (1908 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1W5C968	A0A1W5C970	A0A1W5C968	A0A1W5C970	AGAP009938-PA.	AGAP009937-PA.	0.840
A0A1W5C968	Q7PSH4_ANOGA	A0A1W5C968	Q7PSH4	AGAP009938-PA.	Spectrin beta chain; Belongs to the spectrin family.	0.493
A0A1W5C968	Q7QA48_ANOGA	A0A1W5C968	Q7QA48	AGAP009938-PA.	AGAP004440-PA.	0.555
A0A1W5C970	A0A1W5C968	A0A1W5C970	A0A1W5C968	AGAP009937-PA.	AGAP009938-PA.	0.840
A0A1W5C970	F5HIS1_ANOGA	A0A1W5C970	F5HIS1	AGAP009937-PA.	AGAP002272-PB.	0.901
A0A1W5C970	Q7PSH4_ANOGA	A0A1W5C970	Q7PSH4	AGAP009937-PA.	Spectrin beta chain; Belongs to the spectrin family.	0.493
A0A1W5C970	Q7QA48_ANOGA	A0A1W5C970	Q7QA48	AGAP009937-PA.	AGAP004440-PA.	0.555
A7USX7_ANOGA	Q7QBJ5_ANOGA	A7USX7	Q7QBJ5	AGAP003149-PA.	LanC-like protein 3 homolog.	0.684
A7UVC9_ANOGA	Q5TP19_ANOGA	A7UVC9	Q5TP19	AGAP012240-PA.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.620
A7UVC9_ANOGA	Q7PRC8_ANOGA	A7UVC9	Q7PRC8	AGAP012240-PA.	AGAP002509-PA.	0.449
Actn	Q5TP19_ANOGA	Q7PKQ5	Q5TP19	Alpha-actinin, sarcomeric; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity); Belongs to the alpha-actinin family.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.590
Actn	Q7PRC8_ANOGA	Q7PKQ5	Q7PRC8	Alpha-actinin, sarcomeric; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity); Belongs to the alpha-actinin family.	AGAP002509-PA.	0.425
F5HIS0_ANOGA	Q7PSH4_ANOGA	F5HIS0	Q7PSH4	AGAP002274-PB.	Spectrin beta chain; Belongs to the spectrin family.	0.493
F5HIS0_ANOGA	Q7QA48_ANOGA	F5HIS0	Q7QA48	AGAP002274-PB.	AGAP004440-PA.	0.555
F5HIS1_ANOGA	A0A1W5C970	F5HIS1	A0A1W5C970	AGAP002272-PB.	AGAP009937-PA.	0.901
F5HIS1_ANOGA	Q7PSH4_ANOGA	F5HIS1	Q7PSH4	AGAP002272-PB.	Spectrin beta chain; Belongs to the spectrin family.	0.493
F5HIS1_ANOGA	Q7QA48_ANOGA	F5HIS1	Q7QA48	AGAP002272-PB.	AGAP004440-PA.	0.555
Q5TP19_ANOGA	A7UVC9_ANOGA	Q5TP19	A7UVC9	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	AGAP012240-PA.	0.620
Q5TP19_ANOGA	Actn	Q5TP19	Q7PKQ5	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	Alpha-actinin, sarcomeric; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity); Belongs to the alpha-actinin family.	0.590
Q5TP19_ANOGA	Q7PRC8_ANOGA	Q5TP19	Q7PRC8	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	AGAP002509-PA.	0.656