(13 nodes) Death-like domain superfamily network (Anopheles gambiae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1W5C970	AGAP009937-PA. (1520 aa)
	TUBE	TOLL pathway signalling. (737 aa)
	F5HIS1_ANOGA	AGAP002272-PB. (2550 aa)
	F5HLA1_ANOGA	AGAP003546-PC; Belongs to the MAGUK family. (2577 aa)
	IMD	IMD pathway signalling Immune Deficiency (Imd). (282 aa)
	REL2	IMD pathway signalling NF-kappaB Relish-like transcription factor. (1132 aa)
	Q7PW78_ANOGA	AGAP009061-PA. (912 aa)
	CASPL2	Long caspase (CASPL2); Belongs to the peptidase C14A family. (430 aa)
	MYD	TOLL pathway signalling. (462 aa)
	PELLE	TOLL pathway signalling Ser/Thr kinase. (515 aa)
	Q7QH59_ANOGA	THO complex subunit 1. (709 aa)
	IAP2	Inhibitor of apoptosis 2. (199 aa)
	FADD	IMD pathway signalling Fas-Associated Death Domain (FADD). (255 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1W5C970	F5HIS1_ANOGA	A0A1W5C970	F5HIS1	AGAP009937-PA.	AGAP002272-PB.	0.901
A0A1W5C970	IMD	A0A1W5C970	Q5TS00	AGAP009937-PA.	IMD pathway signalling Immune Deficiency (Imd).	0.747
A0A1W5C970	REL2	A0A1W5C970	Q7PT80	AGAP009937-PA.	IMD pathway signalling NF-kappaB Relish-like transcription factor.	0.937
CASPL2	FADD	Q7Q2Q0	Q7QJ06	Long caspase (CASPL2); Belongs to the peptidase C14A family.	IMD pathway signalling Fas-Associated Death Domain (FADD).	0.479
CASPL2	IAP2	Q7Q2Q0	Q7QHS1	Long caspase (CASPL2); Belongs to the peptidase C14A family.	Inhibitor of apoptosis 2.	0.961
F5HIS1_ANOGA	A0A1W5C970	F5HIS1	A0A1W5C970	AGAP002272-PB.	AGAP009937-PA.	0.901
F5HIS1_ANOGA	IMD	F5HIS1	Q5TS00	AGAP002272-PB.	IMD pathway signalling Immune Deficiency (Imd).	0.747
F5HIS1_ANOGA	REL2	F5HIS1	Q7PT80	AGAP002272-PB.	IMD pathway signalling NF-kappaB Relish-like transcription factor.	0.937
FADD	CASPL2	Q7QJ06	Q7Q2Q0	IMD pathway signalling Fas-Associated Death Domain (FADD).	Long caspase (CASPL2); Belongs to the peptidase C14A family.	0.479
FADD	IAP2	Q7QJ06	Q7QHS1	IMD pathway signalling Fas-Associated Death Domain (FADD).	Inhibitor of apoptosis 2.	0.802
FADD	IMD	Q7QJ06	Q5TS00	IMD pathway signalling Fas-Associated Death Domain (FADD).	IMD pathway signalling Immune Deficiency (Imd).	0.993
FADD	PELLE	Q7QJ06	Q7QD54	IMD pathway signalling Fas-Associated Death Domain (FADD).	TOLL pathway signalling Ser/Thr kinase.	0.447
FADD	REL2	Q7QJ06	Q7PT80	IMD pathway signalling Fas-Associated Death Domain (FADD).	IMD pathway signalling NF-kappaB Relish-like transcription factor.	0.754
IAP2	CASPL2	Q7QHS1	Q7Q2Q0	Inhibitor of apoptosis 2.	Long caspase (CASPL2); Belongs to the peptidase C14A family.	0.961
IAP2	FADD	Q7QHS1	Q7QJ06	Inhibitor of apoptosis 2.	IMD pathway signalling Fas-Associated Death Domain (FADD).	0.802
IAP2	IMD	Q7QHS1	Q5TS00	Inhibitor of apoptosis 2.	IMD pathway signalling Immune Deficiency (Imd).	0.866
IAP2	PELLE	Q7QHS1	Q7QD54	Inhibitor of apoptosis 2.	TOLL pathway signalling Ser/Thr kinase.	0.463
IAP2	REL2	Q7QHS1	Q7PT80	Inhibitor of apoptosis 2.	IMD pathway signalling NF-kappaB Relish-like transcription factor.	0.737
IMD	A0A1W5C970	Q5TS00	A0A1W5C970	IMD pathway signalling Immune Deficiency (Imd).	AGAP009937-PA.	0.747
IMD	F5HIS1_ANOGA	Q5TS00	F5HIS1	IMD pathway signalling Immune Deficiency (Imd).	AGAP002272-PB.	0.747