STRINGSTRING
TRYP2 TRYP2 TRYP3 TRYP3 TRYP4 TRYP4 TRYP5 TRYP5 TRYP6 TRYP6 TRYP7 TRYP7 CecA CecA HexA HexA CHYM2 CHYM2 Def1 Def1 CLIPB7 CLIPB7 CLIPB6 CLIPB6 CLIPB1 CLIPB1 CLIPB3 CLIPB3 CecC CecC CecB CecB ser4 ser4 ser3 ser3 CLIPB4 CLIPB4 Q6VVH1_ANOGA Q6VVH1_ANOGA Q6VVG9_ANOGA Q6VVG9_ANOGA burs124 burs124 Obp71 Obp71 Obp67 Obp67 Def3 Def3 CEC4 CEC4 Q5TUM4_ANOGA Q5TUM4_ANOGA Q7PW37_ANOGA Q7PW37_ANOGA Q7PW39_ANOGA Q7PW39_ANOGA Q7PY64_ANOGA Q7PY64_ANOGA Q7PZ15_ANOGA Q7PZ15_ANOGA Q7PZ19_ANOGA Q7PZ19_ANOGA Q7PZI7_ANOGA Q7PZI7_ANOGA Q7PZT6_ANOGA Q7PZT6_ANOGA Q7Q0K5_ANOGA Q7Q0K5_ANOGA Q7Q1L2_ANOGA Q7Q1L2_ANOGA Q7Q2H9_ANOGA Q7Q2H9_ANOGA Q7Q2S9_ANOGA Q7Q2S9_ANOGA Q7Q3Q7_ANOGA Q7Q3Q7_ANOGA Q7Q3R1_ANOGA Q7Q3R1_ANOGA Q7Q4S0_ANOGA Q7Q4S0_ANOGA Obp70 Obp70 npf npf Q7Q8R3_ANOGA Q7Q8R3_ANOGA Q7Q8R5_ANOGA Q7Q8R5_ANOGA Q7Q8R6_ANOGA Q7Q8R6_ANOGA CLIPB13 CLIPB13 Q7Q9Q5_ANOGA Q7Q9Q5_ANOGA Q7QA39_ANOGA Q7QA39_ANOGA Q7QAI4_ANOGA Q7QAI4_ANOGA CLIPB5 CLIPB5 Q7QCT2_ANOGA Q7QCT2_ANOGA CLIPD6 CLIPD6 Q7QEV3_ANOGA Q7QEV3_ANOGA Q7QEY4_ANOGA Q7QEY4_ANOGA Q7QEY5_ANOGA Q7QEY5_ANOGA Q7QEZ2_ANOGA Q7QEZ2_ANOGA Q7QEZ5_ANOGA Q7QEZ5_ANOGA Q7QF53_ANOGA Q7QF53_ANOGA Q7QFU1_ANOGA Q7QFU1_ANOGA Q7QGJ7_ANOGA Q7QGJ7_ANOGA Q7QGS9_ANOGA Q7QGS9_ANOGA Q7QGX5_ANOGA Q7QGX5_ANOGA pxt pxt Q7QHA9_ANOGA Q7QHA9_ANOGA Q7QHC0_ANOGA Q7QHC0_ANOGA Q7QI57_ANOGA Q7QI57_ANOGA Q7QJ95_ANOGA Q7QJ95_ANOGA Q7QJV2_ANOGA Q7QJV2_ANOGA AKH2 AKH2 Q5TSG1_ANOGA Q5TSG1_ANOGA CHYM1 CHYM1 pburs pburs Q5TMW2_ANOGA Q5TMW2_ANOGA Q5TNF5_ANOGA Q5TNF5_ANOGA Q5TP56_ANOGA Q5TP56_ANOGA Q5TQD0_ANOGA Q5TQD0_ANOGA Obp68 Obp68 Obp66 Obp66 ECH ECH CLIPA19 CLIPA19 Q5TS73_ANOGA Q5TS73_ANOGA CLIPB19 CLIPB19 CAP10_ANOGA CAP10_ANOGA CRZ-2 CRZ-2 A0NE82_ANOGA A0NE82_ANOGA A0NFH9_ANOGA A0NFH9_ANOGA A0NG52_ANOGA A0NG52_ANOGA A0NG61_ANOGA A0NG61_ANOGA SKP SKP Q7PFT8_ANOGA Q7PFT8_ANOGA Q7PM75_ANOGA Q7PM75_ANOGA Q7PM77_ANOGA Q7PM77_ANOGA Q7PMV3_ANOGA Q7PMV3_ANOGA Q7PNK1_ANOGA Q7PNK1_ANOGA CLIPB2 CLIPB2 PBAN PBAN Q7PVC0_ANOGA Q7PVC0_ANOGA AKH1 AKH1 Obp72 Obp72 A7UVE5_ANOGA A7UVE5_ANOGA A7UVJ7_ANOGA A7UVJ7_ANOGA CLIPB36 CLIPB36 Obp69 Obp69 CLIPB9 CLIPB9 F7IVQ1_ANOGA F7IVQ1_ANOGA CBPA1_ANOGA CBPA1_ANOGA TRYP1 TRYP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRYP2Trypsin-2; Major function may be to aid in digestion of the blood meal. (277 aa)
TRYP3Trypsin-3; Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female. Belongs to the peptidase S1 family. (275 aa)
TRYP4Trypsin-4; Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female. Belongs to the peptidase S1 family. (275 aa)
TRYP5Trypsin-5; Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female. Belongs to the peptidase S1 family. (274 aa)
TRYP6Trypsin-6; Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female. Belongs to the peptidase S1 family. (273 aa)
TRYP7Trypsin-7; Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female. Belongs to the peptidase S1 family. (267 aa)
CecACecropin-A amidated isoform; Antibacterial activity against several Gram-positive and Gram-negative bacteria. Antifungal activity against A.fumigatus, B.cinerea, F.culmorum, F.oxysporum, N.crassa, C.albicans, C.neoformans and S.cerevisiae. (58 aa)
HexAHexamerin-1.1; Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins. (692 aa)
CHYM2Chymotrypsin-2. (258 aa)
Def1Defensin; Responsible for the anti Gram-positive activity of immune hemolymph; Belongs to the invertebrate defensin family. Type 1 subfamily. (102 aa)
CLIPB7CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (401 aa)
CLIPB6CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (407 aa)
CLIPB1CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (372 aa)
CLIPB3CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (365 aa)
CecCCecropin-C; Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria; Belongs to the cecropin family. (59 aa)
CecBCecropin-B; Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria; Belongs to the cecropin family. (60 aa)
ser4CLIP domain-containing serine protease B14; Serine protease (By similarity). Plays a role in innate immunity against infections by parasite P.berghei and by Gram-negative bacteria such as E.coli. In response to P.berghei infection, contributes to the clearing of parasite ookinetes independent of melanization, an innate immune response which consists in the deposition of melanin pigments on invading pathogens and parasites. May play a role in non-septic wound healing. (375 aa)
ser3CLIP domain-containing serine protease B15; Serine protease (By similarity). Plays a role in innate immunity against infections by parasite P.berghei and by Gram-negative bacteria such as E.coli. In response to P.berghei infection, contributes to the clearing of parasite ookinetes independent of melanization, an innate immune response which consists in the deposition of melanin pigments on invading pathogens and parasites. (364 aa)
CLIPB4CLIP domain-containing serine protease 14D; Probable serine protease which may play a role in immune responses; Belongs to the peptidase S1 family. CLIP subfamily. (360 aa)
Q6VVH1_ANOGAInsulin-like peptide 1. (154 aa)
Q6VVG9_ANOGAInsulin-like peptide 3. (160 aa)
burs124Bursicon; Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading. (163 aa)
Obp71General odorant-binding protein 71; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid; Belongs to the PBP/GOBP family. (228 aa)
Obp67General odorant-binding protein 67; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid; Belongs to the PBP/GOBP family. (204 aa)
Def3Antimicrobial peptide defensin 3; Antibacterial peptide mostly active against Gram-positive bacteria with atypical up-regulation of expression. Belongs to the invertebrate defensin family. (67 aa)
CEC4Cecropin anti-microbial peptide. (67 aa)
Q5TUM4_ANOGAAGAP000687-PA. (375 aa)
Q7PW37_ANOGAAGAP009103-PA. (225 aa)
Q7PW39_ANOGAAGAP009101-PA. (598 aa)
Q7PY64_ANOGAPancreatic triacylglycerol lipase. (340 aa)
Q7PZ15_ANOGAAGAP011681-PA. (215 aa)
Q7PZ19_ANOGAAGAP011682-PA. (584 aa)
Q7PZI7_ANOGABone morphogenetic protein 7. (441 aa)
Q7PZT6_ANOGAAGAP012076-PA. (133 aa)
Q7Q0K5_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (840 aa)
Q7Q1L2_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)
Q7Q2H9_ANOGAAGAP010328-PA. (311 aa)
Q7Q2S9_ANOGAPancreatic triacylglycerol lipase. (398 aa)
Q7Q3Q7_ANOGADecapentaplegic. (379 aa)
Q7Q3R1_ANOGAAGAP007991-PA. (587 aa)
Q7Q4S0_ANOGAAGAP000899-PA. (335 aa)
Obp70General odorant-binding protein 70; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid; Belongs to the PBP/GOBP family. (200 aa)
npfNeuropeptide F; An integral part of the sensory system that mediates food signaling, providing the neural basis for the regulation of food response; coordinates larval foraging and social behavior changes during development. May have a hormonal role in females (By similarity). (89 aa)
Q7Q8R3_ANOGAInsulin-like peptide 6. (160 aa)
Q7Q8R5_ANOGAInsulin-like peptide 4. (160 aa)
Q7Q8R6_ANOGAInsulin-like peptide 2. (134 aa)
CLIPB13CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (410 aa)
Q7Q9Q5_ANOGAAGAP005103-PA. (377 aa)
Q7QA39_ANOGAPancreatic triacylglycerol lipase. (393 aa)
Q7QAI4_ANOGACLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (368 aa)
CLIPB5CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (379 aa)
Q7QCT2_ANOGAAGAP002793-PA. (1451 aa)
CLIPD6CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (484 aa)
Q7QEV3_ANOGAAGAP000166-PA. (267 aa)
Q7QEY4_ANOGATriacylglycerol lipase. (524 aa)
Q7QEY5_ANOGATriacylglycerol lipase. (542 aa)
Q7QEZ2_ANOGAAGAP000225-PA. (717 aa)
Q7QEZ5_ANOGAAGAP000228-PA. (666 aa)
Q7QF53_ANOGAAGAP000309-PA. (944 aa)
Q7QFU1_ANOGASecretory phospholipase A2. (523 aa)
Q7QGJ7_ANOGAAGAP011569-PA. (137 aa)
Q7QGS9_ANOGAAGAP010879-PA. (197 aa)
Q7QGX5_ANOGAAGAP010930-PA. (274 aa)
pxtChorion peroxidase; Involved in the formation of a rigid and insoluble egg chorion by catalyzing chorion protein cross-linking through dityrosine formation and phenol oxidase-catalyzed chorion melanization. Belongs to the peroxidase family. XPO subfamily. (767 aa)
Q7QHA9_ANOGASecretory phospholipase A2. (238 aa)
Q7QHC0_ANOGAPancreatic triacylglycerol lipase. (344 aa)
Q7QI57_ANOGAAGAP005289-PA. (121 aa)
Q7QJ95_ANOGAAGAP007370-PA. (299 aa)
Q7QJV2_ANOGAPancreatic triacylglycerol lipase. (554 aa)
AKH2Adipokinetic hormone 2. (113 aa)
Q5TSG1_ANOGAInsulin-like peptide 7. (153 aa)
CHYM1Chymotrypsin-1. (259 aa)
pbursPartner of bursicon; Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading. (153 aa)
Q5TMW2_ANOGACLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (370 aa)
Q5TNF5_ANOGAAGAP009104-PA. (319 aa)
Q5TP56_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (456 aa)
Q5TQD0_ANOGAAGAP008302-PA. (171 aa)
Obp68General odorant-binding protein 68; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid; Belongs to the PBP/GOBP family. (212 aa)
Obp66General odorant-binding protein 66; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid; Belongs to the PBP/GOBP family. (212 aa)
ECHEclosion hormone; Neuropeptide that triggers the performance of ecdysis behaviors at the end of a molt. It triggers adult behavior patterns: larval, pupal and adult ecdysis, and plasticization during the molt. Belongs to the insect eclosion hormone family. (91 aa)
CLIPA19CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (356 aa)
Q5TS73_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
CLIPB19CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (367 aa)
CAP10_ANOGAO-glucosyltransferase rumi homolog; Protein O-glucosyltransferase. Catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue found in the consensus sequence C-X-S-X-[PA]-C in epidermal growth factor-like repeats. Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch. (399 aa)
CRZ-2Corazonin precursor-related peptide; Cardioactive peptide. Corazonin is probably involved in the physiological regulation of the heart beat (By similarity). (171 aa)
A0NE82_ANOGAAGAP005000-PA. (284 aa)
A0NFH9_ANOGAAGAP004730-PA. (188 aa)
A0NG52_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
A0NG61_ANOGAAGAP003319-PA. (214 aa)
SKPSulfakinin neuropeptide. (194 aa)
Q7PFT8_ANOGAPancreatic triacylglycerol lipase. (365 aa)
Q7PM75_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
Q7PM77_ANOGAProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Q7PMV3_ANOGASecretory phospholipase A2. (243 aa)
Q7PNK1_ANOGABone morphogenetic protein 5. (442 aa)
CLIPB2CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (355 aa)
PBANPBAN-type neuropeptides; A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity) (By similarity). Belongs to the pyrokinin family. (187 aa)
Q7PVC0_ANOGAAGAP011683-PA. (580 aa)
AKH1AGAP008834-PA. (86 aa)
Obp72General odorant-binding protein 72; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid; Belongs to the PBP/GOBP family. (121 aa)
A7UVE5_ANOGACLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (197 aa)
A7UVJ7_ANOGASalivary lipase. (330 aa)
CLIPB36CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (394 aa)
Obp69General odorant-binding protein 69; Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid; Belongs to the PBP/GOBP family. (229 aa)
CLIPB9CLIP domain-containing serine protease; Belongs to the peptidase S1 family. CLIP subfamily. (401 aa)
F7IVQ1_ANOGAAGAP000342-PA. (321 aa)
CBPA1_ANOGAZinc carboxypeptidase A 1; Involved in the digestion of the blood meal. (433 aa)
TRYP1Trypsin-1; Major function may be to aid in digestion of the blood meal. (274 aa)
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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