63 items (Anopheles gambiae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Q8T0Y8_ANOGA	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
	A0A1W5CAE5	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (278 aa)
	A0NBU4_ANOGA	AGAP011151-PA. (85 aa)
	A0NCV0_ANOGA	AGAP010449-PA. (126 aa)
	A0T4G5_ANOGA	26S proteasome regulatory subunit T2; Belongs to the AAA ATPase family. (438 aa)
	A7USG9_ANOGA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (700 aa)
	F7IUE6_ANOGA	Polyubiquitin-C. (1065 aa)
	Dox-A2	Probable 26S proteasome non-ATPase regulatory subunit 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (496 aa)
	gambif1	AGAP009515-PA. (696 aa)
	IKK1	AGAP009166-PA. (794 aa)
	Q5TPC4_ANOGA	AGAP009628-PA. (324 aa)
	Q5TRL0_ANOGA	26S proteasome 26S non-ATPase subunit N5. (463 aa)
	Q5TTS2_ANOGA	AGAP002481-PA. (875 aa)
	Q5TUI7_ANOGA	Proteasome subunit beta. (284 aa)
	Q7PGR3_ANOGA	26S proteasome regulatory subunit T3; Belongs to the AAA ATPase family. (412 aa)
	Q7PHX7_ANOGA	Ubiquitin-conjugating enzyme E2 R; Belongs to the ubiquitin-conjugating enzyme family. (239 aa)
	Q7PMD7_ANOGA	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (275 aa)
	Q7PMI0_ANOGA	AGAP010135-PA. (391 aa)
	Q7PNC6_ANOGA	AGAP008007-PA; Belongs to the cullin family. (736 aa)
	Q7PNN9_ANOGA	26S proteasome 26S non-ATPase subunit N10. (414 aa)
	Q7PNU4_ANOGA	AGAP006236-PA. (265 aa)
	Q7PPI7_ANOGA	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (259 aa)
	Q7PPM9_ANOGA	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (242 aa)
	Q7PR02_ANOGA	AGAP002599-PA. (305 aa)
	Q7PRY1_ANOGA	E2 ubiquitin-conjugating enzyme E2D, effete; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	REL2	IMD pathway signalling NF-kappaB Relish-like transcription factor. (1132 aa)
	Q7PTA8_ANOGA	26S proteasome regulatory subunit T6; Belongs to the AAA ATPase family. (403 aa)
	Q7PUS4_ANOGA	26S proteasome 26S non-ATPase subunit N7. (389 aa)
	Q7PUX5_ANOGA	AGAP001471-PA. (567 aa)
	Q7PV64_ANOGA	Growth factor receptor-binding protein 2. (211 aa)
	Q7PVI0_ANOGA	Proteasome subunit beta. (229 aa)
	Q7PWV4_ANOGA	Proteasome subunit beta. (207 aa)
	Q7PXH7_ANOGA	26S proteasome regulatory subunit T4; Belongs to the AAA ATPase family. (392 aa)
	Q7PXJ8_ANOGA	26S proteasome 26S non-ATPase subunit N6. (416 aa)
	Q7PXN4_ANOGA	26S proteasome non-ATPase regulatory subunit 5. (489 aa)
	Q7PXW2_ANOGA	AGAP001626-PA. (206 aa)
	Q7PXY1_ANOGA	26S proteasome 26S non-ATPase subunit N9. (380 aa)
	Q7PY13_ANOGA	Proteasome subunit beta. (205 aa)
	Q7PY49_ANOGA	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1040 aa)
	Q7PY81_ANOGA	P21-activated kinase 1. (531 aa)
	Q7PYH7_ANOGA	AGAP001944-PA. (590 aa)
	Q7PZD3_ANOGA	AGAP011849-PA. (398 aa)
	Q7PZX6_ANOGA	26S proteasome 26S non-ATPase subunit N8. (338 aa)
	Q7Q1N6_ANOGA	AGAP009703-PA. (289 aa)
	Q7Q2B0_ANOGA	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa)
	Q7Q306_ANOGA	Proteasome subunit beta. (279 aa)
	Q7Q320_ANOGA	Proteasome subunit beta; Belongs to the peptidase T1B family. (271 aa)
	Q7Q3K7_ANOGA	60S ribosomal protein L40. (128 aa)
	Q7Q4A9_ANOGA	Tyrosine-protein kinase. (599 aa)
	Q7Q797_ANOGA	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (249 aa)
	Q7Q8A7_ANOGA	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (162 aa)
	Q7Q8I2_ANOGA	26S proteasome 26S non-ATPase subunit N11. (311 aa)
	Q7QCF8_ANOGA	26S proteasome 26S non-ATPase subunit N12. (262 aa)
	Q7QD76_ANOGA	Non-specific serine/threonine protein kinase. (794 aa)
	Q7QDV9_ANOGA	AGAP010447-PA. (187 aa)
	Q7QEX9_ANOGA	26S proteasome non-ATPase regulatory subunit 9. (211 aa)
	Q7QF52_ANOGA	Proteasome activator subunit 3 (PA28 gamma). (264 aa)
	Q7QFQ3_ANOGA	26S proteasome regulatory subunit T5; Belongs to the AAA ATPase family. (427 aa)
	Q7QGI8_ANOGA	26S proteasome regulatory subunit T5. (431 aa)
	Q7QHE3_ANOGA	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1232 aa)
	Q7QHG0_ANOGA	26S proteasome regulatory subunit T1; Belongs to the AAA ATPase family. (434 aa)
	Q7QJC6_ANOGA	Proteasome inhibitor subunit 1 (PI31). (269 aa)
	Q7QLL8_ANOGA	Proteasome subunit beta; Belongs to the peptidase T1B family. (271 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1W5CAE5	A0NCV0_ANOGA	A0A1W5CAE5	A0NCV0	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	AGAP010449-PA.	0.851
A0A1W5CAE5	A0T4G5_ANOGA	A0A1W5CAE5	A0T4G5	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	26S proteasome regulatory subunit T2; Belongs to the AAA ATPase family.	0.998
A0A1W5CAE5	Dox-A2	A0A1W5CAE5	O61470	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Probable 26S proteasome non-ATPase regulatory subunit 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.994
A0A1W5CAE5	F7IUE6_ANOGA	A0A1W5CAE5	F7IUE6	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Polyubiquitin-C.	0.808
A0A1W5CAE5	Q5TPC4_ANOGA	A0A1W5CAE5	Q5TPC4	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	AGAP009628-PA.	0.404
A0A1W5CAE5	Q5TRL0_ANOGA	A0A1W5CAE5	Q5TRL0	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	26S proteasome 26S non-ATPase subunit N5.	0.997
A0A1W5CAE5	Q5TTS2_ANOGA	A0A1W5CAE5	Q5TTS2	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	AGAP002481-PA.	0.997
A0A1W5CAE5	Q5TUI7_ANOGA	A0A1W5CAE5	Q5TUI7	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Proteasome subunit beta.	0.999
A0A1W5CAE5	Q7PGR3_ANOGA	A0A1W5CAE5	Q7PGR3	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	26S proteasome regulatory subunit T3; Belongs to the AAA ATPase family.	0.991
A0A1W5CAE5	Q7PMD7_ANOGA	A0A1W5CAE5	Q7PMD7	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.999
A0A1W5CAE5	Q7PNC6_ANOGA	A0A1W5CAE5	Q7PNC6	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	AGAP008007-PA; Belongs to the cullin family.	0.499
A0A1W5CAE5	Q7PNN9_ANOGA	A0A1W5CAE5	Q7PNN9	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	26S proteasome 26S non-ATPase subunit N10.	0.998
A0A1W5CAE5	Q7PPI7_ANOGA	A0A1W5CAE5	Q7PPI7	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.999
A0A1W5CAE5	Q7PPM9_ANOGA	A0A1W5CAE5	Q7PPM9	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.999
A0A1W5CAE5	Q7PR02_ANOGA	A0A1W5CAE5	Q7PR02	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	AGAP002599-PA.	0.808
A0A1W5CAE5	Q7PRY1_ANOGA	A0A1W5CAE5	Q7PRY1	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	E2 ubiquitin-conjugating enzyme E2D, effete; Belongs to the ubiquitin-conjugating enzyme family.	0.454
A0A1W5CAE5	Q7PTA8_ANOGA	A0A1W5CAE5	Q7PTA8	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	26S proteasome regulatory subunit T6; Belongs to the AAA ATPase family.	0.995
A0A1W5CAE5	Q7PUS4_ANOGA	A0A1W5CAE5	Q7PUS4	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	26S proteasome 26S non-ATPase subunit N7.	0.997
A0A1W5CAE5	Q7PVI0_ANOGA	A0A1W5CAE5	Q7PVI0	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Proteasome subunit beta.	0.999
A0A1W5CAE5	Q7PWV4_ANOGA	A0A1W5CAE5	Q7PWV4	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	Proteasome subunit beta.	0.999