STRINGSTRING
Q7QID8_ANOGA Q7QID8_ANOGA A0A1W5C8U9 A0A1W5C8U9 A0A1W5C995 A0A1W5C995 A0NBL4_ANOGA A0NBL4_ANOGA A0NBP3_ANOGA A0NBP3_ANOGA A0NCA9_ANOGA A0NCA9_ANOGA A0NCV0_ANOGA A0NCV0_ANOGA A0NDB2_ANOGA A0NDB2_ANOGA A0NGD8_ANOGA A0NGD8_ANOGA A0NH40_ANOGA A0NH40_ANOGA A7UR94_ANOGA A7UR94_ANOGA A7USV1_ANOGA A7USV1_ANOGA A7UU35_ANOGA A7UU35_ANOGA A7UUK1_ANOGA A7UUK1_ANOGA A7UV10_ANOGA A7UV10_ANOGA F5HJ78_ANOGA F5HJ78_ANOGA F5HKE1_ANOGA F5HKE1_ANOGA F7IUE6_ANOGA F7IUE6_ANOGA Q5TMJ5_ANOGA Q5TMJ5_ANOGA Q5TPC2_ANOGA Q5TPC2_ANOGA Q5TSV8_ANOGA Q5TSV8_ANOGA Q5TV84_ANOGA Q5TV84_ANOGA CPR140 CPR140 Q5TX00_ANOGA Q5TX00_ANOGA AGAP002259 AGAP002259 Q7PCX0_ANOGA Q7PCX0_ANOGA Q7PNM8_ANOGA Q7PNM8_ANOGA Q7PNU4_ANOGA Q7PNU4_ANOGA Q7PR02_ANOGA Q7PR02_ANOGA Q7PRC7_ANOGA Q7PRC7_ANOGA CPR122 CPR122 Q7PWV5_ANOGA Q7PWV5_ANOGA Q7PX53_ANOGA Q7PX53_ANOGA Q7PX96_ANOGA Q7PX96_ANOGA Q7PXI6_ANOGA Q7PXI6_ANOGA Q7PXL0_ANOGA Q7PXL0_ANOGA Q7PXL4_ANOGA Q7PXL4_ANOGA Q7PXS0_ANOGA Q7PXS0_ANOGA Q7PXS8_ANOGA Q7PXS8_ANOGA Q7Q0E8_ANOGA Q7Q0E8_ANOGA Q7Q111_ANOGA Q7Q111_ANOGA Q7Q2C5_ANOGA Q7Q2C5_ANOGA Fen1 Fen1 Q7Q3Z9_ANOGA Q7Q3Z9_ANOGA Q7Q4D7_ANOGA Q7Q4D7_ANOGA Q7Q6V4_ANOGA Q7Q6V4_ANOGA Q7Q6V5_ANOGA Q7Q6V5_ANOGA Q7Q8E2_ANOGA Q7Q8E2_ANOGA Q7QAJ3_ANOGA Q7QAJ3_ANOGA Q7QB22_ANOGA Q7QB22_ANOGA Q7QBC7_ANOGA Q7QBC7_ANOGA Q7QCA1_ANOGA Q7QCA1_ANOGA Q7QCF7_ANOGA Q7QCF7_ANOGA Q7QCK4_ANOGA Q7QCK4_ANOGA Q7QCQ6_ANOGA Q7QCQ6_ANOGA Q7QD57_ANOGA Q7QD57_ANOGA Q7QDV9_ANOGA Q7QDV9_ANOGA Q7QFY4_ANOGA Q7QFY4_ANOGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Q7QID8_ANOGADouble-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (655 aa)
A0A1W5C8U9AGAP012158-PA. (220 aa)
A0A1W5C995AGAP012157-PA. (207 aa)
A0NBL4_ANOGABreast cancer 2 susceptibility protein. (2037 aa)
A0NBP3_ANOGADNA-repair protein XRCC2. (310 aa)
A0NCA9_ANOGARAD51-like protein 2. (290 aa)
A0NCV0_ANOGAAGAP010449-PA. (126 aa)
A0NDB2_ANOGAAGAP003213-PA. (778 aa)
A0NGD8_ANOGATIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (289 aa)
A0NH40_ANOGAAGAP001467-PA. (1301 aa)
A7UR94_ANOGAAGAP007582-PA. (1158 aa)
A7USV1_ANOGASerine/threonine-protein phosphatase 4 regulatory subunit 2. (647 aa)
A7UU35_ANOGAAGAP006164-PA. (315 aa)
A7UUK1_ANOGAAGAP008288-PA. (1263 aa)
A7UV10_ANOGAAGAP010787-PA. (1154 aa)
F5HJ78_ANOGAAGAP013180-PA. (266 aa)
F5HKE1_ANOGADNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (339 aa)
F7IUE6_ANOGAPolyubiquitin-C. (1065 aa)
Q5TMJ5_ANOGAAGAP011675-PA. (643 aa)
Q5TPC2_ANOGAAGAP009632-PA; Belongs to the PI3/PI4-kinase family. (1128 aa)
Q5TSV8_ANOGACyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (309 aa)
Q5TV84_ANOGAWerner Syndrome-like exonuclease. (292 aa)
CPR140Cuticular protein RR-1 family 140. (856 aa)
Q5TX00_ANOGADNA polymerase theta. (1997 aa)
AGAP002259Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (273 aa)
Q7PCX0_ANOGAHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
Q7PNM8_ANOGAAGAP005917-PA. (1566 aa)
Q7PNU4_ANOGAAGAP006236-PA. (265 aa)
Q7PR02_ANOGAAGAP002599-PA. (305 aa)
Q7PRC7_ANOGACrossover junction endonuclease. (313 aa)
CPR122Cuticular protein RR-2 family 122. (138 aa)
Q7PWV5_ANOGAAGAP008836-PA. (449 aa)
Q7PX53_ANOGANAD-dependent deacetylase sirtuin 7. (783 aa)
Q7PX96_ANOGAAGAP001292-PA. (706 aa)
Q7PXI6_ANOGAReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (612 aa)
Q7PXL0_ANOGAMono-ADP-ribosyltransferase sirtuin 6. (354 aa)
Q7PXL4_ANOGAAGAP001466-PA. (321 aa)
Q7PXS0_ANOGAHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (457 aa)
Q7PXS8_ANOGAAGAP001549-PA. (824 aa)
Q7Q0E8_ANOGAAGAP012413-PA; Belongs to the cyclin family. (350 aa)
Q7Q111_ANOGADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1025 aa)
Q7Q2C5_ANOGAHistone H2B; Belongs to the histone H2B family. (91 aa)
Fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
Q7Q3Z9_ANOGAAGAP008118-PA. (505 aa)
Q7Q4D7_ANOGAAGAP008351-PA. (272 aa)
Q7Q6V4_ANOGAAGAP005649-PA. (958 aa)
Q7Q6V5_ANOGAAGAP005648-PA. (143 aa)
Q7Q8E2_ANOGAAGAP008673-PA. (408 aa)
Q7QAJ3_ANOGADNA repair protein RAD50. (1308 aa)
Q7QB22_ANOGAAGAP004229-PA. (2085 aa)
Q7QBC7_ANOGAPoly [ADP-ribose] polymerase. (995 aa)
Q7QCA1_ANOGACell cycle checkpoint control protein RAD9A. (556 aa)
Q7QCF7_ANOGADNA-repair protein XRCC1. (718 aa)
Q7QCK4_ANOGAFlap endonuclease. (733 aa)
Q7QCQ6_ANOGATopoisomerase (DNA) II binding protein 1. (1584 aa)
Q7QD57_ANOGAAsparaginyl-tRNA synthetase. (553 aa)
Q7QDV9_ANOGAAGAP010447-PA. (187 aa)
Q7QFY4_ANOGASerine/threonine-protein phosphatase. (307 aa)
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.