28 items (Anopheles gambiae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	Q7Q5S7_ANOGA	Vacuolar protein sorting 20. (214 aa)
	A0NCV0_ANOGA	AGAP010449-PA. (126 aa)
	A7UTK9_ANOGA	AGAP005315-PA. (131 aa)
	A7UTY4_ANOGA	AGAP005919-PA. (580 aa)
	F7IUE6_ANOGA	Polyubiquitin-C. (1065 aa)
	Q5TPR5_ANOGA	Vacuolar protein sorting 36. (396 aa)
	Q5TVC9_ANOGA	Vacuolar protein sorting 37B. (230 aa)
	Q7PNF5_ANOGA	AGAP008494-PA. (685 aa)
	Q7PNU4_ANOGA	AGAP006236-PA. (265 aa)
	Q7PR02_ANOGA	AGAP002599-PA. (305 aa)
	Q7PTK1_ANOGA	AGAP002222-PA. (685 aa)
	Q7PUC1_ANOGA	Vacuolar protein sorting 4. (232 aa)
	Q7PWQ2_ANOGA	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (731 aa)
	Q7PYP0_ANOGA	Zinc finger, FYVE domain containing 1. (844 aa)
	Q7Q2J5_ANOGA	Charged multivesicular body protein 7. (454 aa)
	Q7Q2L3_ANOGA	ESCRT-I complex subunit MVB12. (297 aa)
	Q7Q358_ANOGA	AGAP011497-PA. (171 aa)
	Q7Q3K7_ANOGA	60S ribosomal protein L40. (128 aa)
	Q7Q660_ANOGA	AGAP006029-PA. (236 aa)
	Q7Q6B6_ANOGA	Tumor susceptibility 101 protein. (395 aa)
	Q7Q7F1_ANOGA	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (210 aa)
	Q7Q7G8_ANOGA	Charged multivesicular body protein 4. (225 aa)
	Q7Q9Q8_ANOGA	Vacuolar protein sorting 60. (225 aa)
	Q7QCB0_ANOGA	ESCRT-I complex subunit VPS37. (321 aa)
	Q7QDV9_ANOGA	AGAP010447-PA. (187 aa)
	Q7QE89_ANOGA	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (250 aa)
	Q7QH42_ANOGA	Vacuolar protein sorting 24. (221 aa)
	Q7QJJ1_ANOGA	Vacuolar protein sorting-associated protein VTA1. (317 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0NCV0_ANOGA	F7IUE6_ANOGA	A0NCV0	F7IUE6	AGAP010449-PA.	Polyubiquitin-C.	0.591
A0NCV0_ANOGA	Q5TPR5_ANOGA	A0NCV0	Q5TPR5	AGAP010449-PA.	Vacuolar protein sorting 36.	0.852
A0NCV0_ANOGA	Q7PNF5_ANOGA	A0NCV0	Q7PNF5	AGAP010449-PA.	AGAP008494-PA.	0.801
A0NCV0_ANOGA	Q7PNU4_ANOGA	A0NCV0	Q7PNU4	AGAP010449-PA.	AGAP006236-PA.	0.567
A0NCV0_ANOGA	Q7PR02_ANOGA	A0NCV0	Q7PR02	AGAP010449-PA.	AGAP002599-PA.	0.591
A0NCV0_ANOGA	Q7PWQ2_ANOGA	A0NCV0	Q7PWQ2	AGAP010449-PA.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.702
A0NCV0_ANOGA	Q7PYP0_ANOGA	A0NCV0	Q7PYP0	AGAP010449-PA.	Zinc finger, FYVE domain containing 1.	0.702
A0NCV0_ANOGA	Q7Q2L3_ANOGA	A0NCV0	Q7Q2L3	AGAP010449-PA.	ESCRT-I complex subunit MVB12.	0.455
A0NCV0_ANOGA	Q7Q3K7_ANOGA	A0NCV0	Q7Q3K7	AGAP010449-PA.	60S ribosomal protein L40.	0.993
A0NCV0_ANOGA	Q7Q6B6_ANOGA	A0NCV0	Q7Q6B6	AGAP010449-PA.	Tumor susceptibility 101 protein.	0.920
A0NCV0_ANOGA	Q7Q7F1_ANOGA	A0NCV0	Q7Q7F1	AGAP010449-PA.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.543
A0NCV0_ANOGA	Q7Q9Q8_ANOGA	A0NCV0	Q7Q9Q8	AGAP010449-PA.	Vacuolar protein sorting 60.	0.410
A0NCV0_ANOGA	Q7QDV9_ANOGA	A0NCV0	Q7QDV9	AGAP010449-PA.	AGAP010447-PA.	0.900
A0NCV0_ANOGA	Q7QE89_ANOGA	A0NCV0	Q7QE89	AGAP010449-PA.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.610
A7UTK9_ANOGA	Q5TPR5_ANOGA	A7UTK9	Q5TPR5	AGAP005315-PA.	Vacuolar protein sorting 36.	0.736
A7UTK9_ANOGA	Q5TVC9_ANOGA	A7UTK9	Q5TVC9	AGAP005315-PA.	Vacuolar protein sorting 37B.	0.646
A7UTK9_ANOGA	Q7PUC1_ANOGA	A7UTK9	Q7PUC1	AGAP005315-PA.	Vacuolar protein sorting 4.	0.966
A7UTK9_ANOGA	Q7PWQ2_ANOGA	A7UTK9	Q7PWQ2	AGAP005315-PA.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.516
A7UTK9_ANOGA	Q7Q2J5_ANOGA	A7UTK9	Q7Q2J5	AGAP005315-PA.	Charged multivesicular body protein 7.	0.843
A7UTK9_ANOGA	Q7Q2L3_ANOGA	A7UTK9	Q7Q2L3	AGAP005315-PA.	ESCRT-I complex subunit MVB12.	0.549