(16 nodes) (2014) Population genetics of Anopheles coluzzii immune pathways and genes. network (Anopheles gambiae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gambif1	AGAP009515-PA. (696 aa)
	CASPL1	AGAP011693-PA; Belongs to the peptidase C14A family. (468 aa)
	IKK1	AGAP009166-PA. (794 aa)
	IMD	IMD pathway signalling Immune Deficiency (Imd). (282 aa)
	GNBPB1	3-glucan binding protein. (395 aa)
	REL2	IMD pathway signalling NF-kappaB Relish-like transcription factor. (1132 aa)
	TEP1	AGAP010815-PA. (1028 aa)
	CACT	Protein cactus (TOLL pathway signalling). (377 aa)
	CTL4	C-type lectin (CTL). (177 aa)
	CTLMA2	C-type lectin (CTL) - mannose binding. (174 aa)
	TEP1-2	AGAP010815-PA. (181 aa)
	PELLE	TOLL pathway signalling Ser/Thr kinase. (515 aa)
	TRAF6	AGAP000388-PA. (478 aa)
	IAP2	Inhibitor of apoptosis 2. (199 aa)
	FADD	IMD pathway signalling Fas-Associated Death Domain (FADD). (255 aa)
	Toll	TOLL-like receptor 1A; Belongs to the Toll-like receptor family. (1152 aa)

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACT	CASPL1	Q7Q3L5	Q5TMK1	Protein cactus (TOLL pathway signalling).	AGAP011693-PA; Belongs to the peptidase C14A family.	0.415
CACT	FADD	Q7Q3L5	Q7QJ06	Protein cactus (TOLL pathway signalling).	IMD pathway signalling Fas-Associated Death Domain (FADD).	0.459
CACT	IKK1	Q7Q3L5	Q5TNB7	Protein cactus (TOLL pathway signalling).	AGAP009166-PA.	0.894
CACT	IMD	Q7Q3L5	Q5TS00	Protein cactus (TOLL pathway signalling).	IMD pathway signalling Immune Deficiency (Imd).	0.499
CACT	PELLE	Q7Q3L5	Q7QD54	Protein cactus (TOLL pathway signalling).	TOLL pathway signalling Ser/Thr kinase.	0.946
CACT	TRAF6	Q7Q3L5	Q7QFB1	Protein cactus (TOLL pathway signalling).	AGAP000388-PA.	0.420
CACT	Toll	Q7Q3L5	Q8WRE5	Protein cactus (TOLL pathway signalling).	TOLL-like receptor 1A; Belongs to the Toll-like receptor family.	0.635
CACT	gambif1	Q7Q3L5	Q17034	Protein cactus (TOLL pathway signalling).	AGAP009515-PA.	0.988
CASPL1	CACT	Q5TMK1	Q7Q3L5	AGAP011693-PA; Belongs to the peptidase C14A family.	Protein cactus (TOLL pathway signalling).	0.415
CASPL1	FADD	Q5TMK1	Q7QJ06	AGAP011693-PA; Belongs to the peptidase C14A family.	IMD pathway signalling Fas-Associated Death Domain (FADD).	0.986
CASPL1	IAP2	Q5TMK1	Q7QHS1	AGAP011693-PA; Belongs to the peptidase C14A family.	Inhibitor of apoptosis 2.	0.588
CASPL1	IKK1	Q5TMK1	Q5TNB7	AGAP011693-PA; Belongs to the peptidase C14A family.	AGAP009166-PA.	0.523
CASPL1	IMD	Q5TMK1	Q5TS00	AGAP011693-PA; Belongs to the peptidase C14A family.	IMD pathway signalling Immune Deficiency (Imd).	0.972
CASPL1	REL2	Q5TMK1	Q7PT80	AGAP011693-PA; Belongs to the peptidase C14A family.	IMD pathway signalling NF-kappaB Relish-like transcription factor.	0.719
CASPL1	TRAF6	Q5TMK1	Q7QFB1	AGAP011693-PA; Belongs to the peptidase C14A family.	AGAP000388-PA.	0.425
CTL4	CTLMA2	Q7Q7F7	Q7Q7F8	C-type lectin (CTL).	C-type lectin (CTL) - mannose binding.	0.554
CTL4	TEP1	Q7Q7F7	Q7Q253	C-type lectin (CTL).	AGAP010815-PA.	0.651
CTL4	TEP1-2	Q7Q7F7	Q7Q7S9	C-type lectin (CTL).	AGAP010815-PA.	0.701
CTLMA2	CTL4	Q7Q7F8	Q7Q7F7	C-type lectin (CTL) - mannose binding.	C-type lectin (CTL).	0.554
CTLMA2	TEP1	Q7Q7F8	Q7Q253	C-type lectin (CTL) - mannose binding.	AGAP010815-PA.	0.604