(21 nodes) Glycosylphosphatidylinositol (GPI)-anchor biosynthesis network (Anopheles albimanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

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protein homology

Your Input:
	A0A182FE21	Uncharacterized protein. (248 aa)
	A0A182FA54	Uncharacterized protein. (178 aa)
	A0A182F9T7	Uncharacterized protein. (1145 aa)
	A0A182F9K1	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (345 aa)
	A0A182F879	Uncharacterized protein. (342 aa)
	A0A182F4R3	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (470 aa)
	A0A1Y9G9R4	TM2 domain-containing protein. (186 aa)
	A0A1Y9G9J2	Uncharacterized protein. (517 aa)
	A0A182FVE9	Uncharacterized protein. (487 aa)
	A0A182FUD7	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (2016 aa)
	A0A182FUC8	Uncharacterized protein. (641 aa)
	A0A182FSK5	PigN domain-containing protein. (871 aa)
	A0A182FSD8	Mannosyltransferase. (529 aa)
	A0A182FNT1	Fe2OG dioxygenase domain-containing protein. (1039 aa)
	A0A182FNB1	Uncharacterized protein. (594 aa)
	A0A182FM36	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (444 aa)
	A0A182FLN6	Uncharacterized protein. (670 aa)
	A0A182FLK3	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (971 aa)
	A0A182FHX5	Uncharacterized protein. (243 aa)
	A0A182FF46	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (608 aa)
	A0A182FDW9	Uncharacterized protein. (278 aa)

Your Current Organism:

Anopheles albimanus

NCBI taxonomy Id: 7167
Other names: A. albimanus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182F4R3	A0A182F879	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	Uncharacterized protein.	0.913
A0A182F4R3	A0A182FLN6	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	Uncharacterized protein.	0.414
A0A182F4R3	A0A182FM36	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.	0.917
A0A182F4R3	A0A182FSK5	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	PigN domain-containing protein.	0.595
A0A182F4R3	A0A182FUD7	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family.	0.422
A0A182F879	A0A182F4R3	Uncharacterized protein.	Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.	0.913
A0A182F879	A0A182F9K1	Uncharacterized protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.590
A0A182F879	A0A182F9T7	Uncharacterized protein.	Uncharacterized protein.	0.575
A0A182F879	A0A182FA54	Uncharacterized protein.	Uncharacterized protein.	0.951
A0A182F879	A0A182FDW9	Uncharacterized protein.	Uncharacterized protein.	0.954
A0A182F879	A0A182FE21	Uncharacterized protein.	Uncharacterized protein.	0.495
A0A182F879	A0A182FF46	Uncharacterized protein.	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.631
A0A182F879	A0A182FLN6	Uncharacterized protein.	Uncharacterized protein.	0.560
A0A182F879	A0A182FM36	Uncharacterized protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.	0.727
A0A182F879	A0A182FNB1	Uncharacterized protein.	Uncharacterized protein.	0.533
A0A182F879	A0A182FSD8	Uncharacterized protein.	Mannosyltransferase.	0.607
A0A182F879	A0A182FSK5	Uncharacterized protein.	PigN domain-containing protein.	0.568
A0A182F879	A0A182FUC8	Uncharacterized protein.	Uncharacterized protein.	0.587
A0A182F879	A0A182FUD7	Uncharacterized protein.	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family.	0.463
A0A182F879	A0A182FVE9	Uncharacterized protein.	Uncharacterized protein.	0.958