STRINGSTRING
ARN74743.1 ARN74743.1 ARN76356.1 ARN76356.1 ubiE ubiE ARN74064.1 ARN74064.1 ARN74062.1 ARN74062.1 ARN73856.1 ARN73856.1 ARN73422.1 ARN73422.1 ARN73293.1 ARN73293.1 glcB glcB aceK aceK ARN73163.1 ARN73163.1 ARN73136.1 ARN73136.1 ARN73106.1 ARN73106.1 ARN73319.1 ARN73319.1 ARN76128.1 ARN76128.1 ARN76127.1 ARN76127.1 ARN76126.1 ARN76126.1 ARN76512.1 ARN76512.1 sdhB sdhB ARN76511.1 ARN76511.1 sucC sucC sucD sucD BST96_18545 BST96_18545 ARN75914.1 ARN75914.1 ARN75876.1 ARN75876.1 ARN75788.1 ARN75788.1 ARN75787.1 ARN75787.1 ARN75630.1 ARN75630.1 nqrE nqrE nqrB nqrB ARN76459.1 ARN76459.1 ARN75505.1 ARN75505.1 mdh mdh ARN74874.1 ARN74874.1 ARN74746.1 ARN74746.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARN74743.1Cytochrome-c oxidase, cbb3-type subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family. (480 aa)
ARN76356.1Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
ubiEBifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (251 aa)
ARN74064.1Cytochrome c oxidase subunit 3; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
ARN74062.1Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (519 aa)
ARN73856.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
ARN73422.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
ARN73293.1Ubiquinone-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (719 aa)
aceKBifunctional isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (570 aa)
ARN73163.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
ARN73136.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
ARN73106.1Tat pathway signal protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
ARN73319.1Periplasmic nitrate reductase electron transfer subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (151 aa)
ARN76128.1Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (428 aa)
ARN76127.1Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
ARN76126.1Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (128 aa)
ARN76512.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (587 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
ARN76511.12-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (939 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
BST96_18545Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (933 aa)
ARN75914.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
ARN75876.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (715 aa)
ARN75788.1Isocitrate dehydrogenase (NADP(+)); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (742 aa)
ARN75787.1NADP-dependent isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
ARN75630.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (721 aa)
nqrENADH:ubiquinone reductase (Na(+)-transporting) subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (204 aa)
nqrBNADH:ubiquinone reductase (Na(+)-transporting) subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (404 aa)
ARN76459.1Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (551 aa)
ARN75505.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (326 aa)
ARN74874.1Ubiquinol-cytochrome C reductase; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (744 aa)
ARN74746.1Cytochrome-c oxidase, cbb3-type subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (298 aa)
Your Current Organism:
Oceanicoccus sagamiensis
NCBI taxonomy Id: 716816
Other names: KCTC 23278, NBRC 107125, O. sagamiensis, gamma proteobacterium PZ-5, strain PZ-5
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.