STRINGSTRING
ARN73017.1 ARN73017.1 ARN73085.1 ARN73085.1 ARN76271.1 ARN76271.1 ARN73108.1 ARN73108.1 ARN73109.1 ARN73109.1 ARN73149.1 ARN73149.1 acsA acsA ARN73544.1 ARN73544.1 ARN73545.1 ARN73545.1 ARN73979.1 ARN73979.1 ARN74114.1 ARN74114.1 ARN74122.1 ARN74122.1 ARN74260.1 ARN74260.1 ackA ackA ARN74614.1 ARN74614.1 accA accA ARN75236.1 ARN75236.1 ARN75268.1 ARN75268.1 ARN75563.1 ARN75563.1 ARN76460.1 ARN76460.1 ARN75569.1 ARN75569.1 ARN75633.1 ARN75633.1 ARN75643.1 ARN75643.1 ARN75650.1 ARN75650.1 ARN75651.1 ARN75651.1 BST96_18545 BST96_18545 accD accD BST96_18790 BST96_18790 BST96_18985 BST96_18985 ARN76020.1 ARN76020.1 ARN76506.1 ARN76506.1 ARN76079.1 ARN76079.1 ARN76080.1 ARN76080.1 sucD sucD sucC sucC ARN76123.1 ARN76123.1 ARN76209.1 ARN76209.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARN73017.1Aspartate aminotransferase family protein; Catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa)
ARN73085.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (783 aa)
ARN76271.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
ARN73108.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
ARN73109.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ARN73149.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa)
ARN73544.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa)
ARN73545.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
ARN73979.1Lactoylglutathione lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
ARN74114.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ARN74122.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
ARN74260.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (505 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (585 aa)
ARN74614.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa)
ARN75236.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ARN75268.1Acetoacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ARN75563.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
ARN76460.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
ARN75569.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
ARN75633.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
ARN75643.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
ARN75650.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ARN75651.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (713 aa)
BST96_18545Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (933 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa)
BST96_18790Putrescine ABC transporter permease PotI; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (466 aa)
BST96_18985Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ARN76020.1Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (714 aa)
ARN76506.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
ARN76079.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (717 aa)
ARN76080.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
ARN76123.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
ARN76209.1Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
Your Current Organism:
Oceanicoccus sagamiensis
NCBI taxonomy Id: 716816
Other names: KCTC 23278, NBRC 107125, O. sagamiensis, gamma proteobacterium PZ-5, strain PZ-5
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.