50 items (Culex quinquefasciatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B0WNV6_CULQU	Vps53 protein. (902 aa)
	B0W1I3_CULQU	Protein expanded. (1382 aa)
	B0W2T8_CULQU	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (745 aa)
	B0W379_CULQU	Sorting nexin, putative. (167 aa)
	B0W3D0_CULQU	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (897 aa)
	B0W4D1_CULQU	Myotubularin, putative. (2003 aa)
	B0W681_CULQU	Calponin-homology (CH) domain-containing protein. (149 aa)
	B0W682_CULQU	Uncharacterized protein. (798 aa)
	B0W683_CULQU	BMERB domain-containing protein. (262 aa)
	B0W782_CULQU	Cxyorf1. (491 aa)
	B0WAH8_CULQU	Uncharacterized protein. (215 aa)
	B0WB30_CULQU	Ubiquitin-conjugating enzyme rad6; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
	B0WC20_CULQU	Vacuolar protein sorting. (888 aa)
	B0WCG3_CULQU	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2467 aa)
	B0WCS3_CULQU	GTP-binding protein YPTC4. (215 aa)
	B0WCV0_CULQU	Uncharacterized protein. (228 aa)
	B0WCV1_CULQU	UDENN domain-containing protein. (902 aa)
	B0WDS8_CULQU	Vacuolar protein sorting-associated protein 18. (572 aa)
	B0WEG6_CULQU	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (762 aa)
	B0WGM0_CULQU	Vacuolar protein sorting, putative. (657 aa)
	B0WHE1_CULQU	Tak1. (812 aa)
	B0WHE2_CULQU	Uncharacterized protein. (1931 aa)
	B0WI65_CULQU	Myotubularin. (548 aa)
	B0WI66_CULQU	Inhibitor of kappab kinase epsilon. (734 aa)
	B0WK55_CULQU	Ras-related protein Rab-8A, putative. (209 aa)
	B0WKP2_CULQU	Uncharacterized protein. (554 aa)
	B0WKP3_CULQU	VPS9 domain-containing protein. (347 aa)
	B0WLA2_CULQU	Exocyst complex component 3. (717 aa)
	B0WM39_CULQU	Merlin/moesin/ezrin/radixin. (594 aa)
	B0WNC3_CULQU	Past-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (536 aa)
	B0WU68_CULQU	Exocyst complex-subunit protein, 84kD-subunit, putative. (673 aa)
	B0WVY7_CULQU	Vacuolar protein sorting-associated protein 26B-B. (532 aa)
	B0WWP0_CULQU	Tyrosine-protein phosphatase non-receptor type 23. (1623 aa)
	B0WWZ9_CULQU	Uncharacterized protein. (665 aa)
	B0WX80_CULQU	FKBP-rapamycin associated protein. (243 aa)
	B0WX81_CULQU	FKBP-rapamycin associated protein. (245 aa)
	B0X024_CULQU	Uncharacterized protein. (960 aa)
	B0X1P7_CULQU	Esophageal cancer associated protein. (952 aa)
	B0X517_CULQU	Uncharacterized protein. (1015 aa)
	B0X5L3_CULQU	Ras-related protein Rab, putative. (203 aa)
	B0X770_CULQU	Uncharacterized protein. (737 aa)
	B0X7E3_CULQU	Uncharacterized protein. (202 aa)
	B0X7E4_CULQU	Blastoderm specific protein 25D, putative. (458 aa)
	B0X8A2_CULQU	Uncharacterized protein. (420 aa)
	B0XGX0_CULQU	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (838 aa)
	B0XI18_CULQU	GTPase_rho. (106 aa)
	B0XIK2_CULQU	Glutamate receptor binding protein, putative. (960 aa)
	B0XJS6_CULQU	FKBP-rapamycin associated protein. (229 aa)
	B0XK08_CULQU	Merlin/moesin/ezrin/radixin. (648 aa)
	B0XKW5_CULQU	PDZ domain-containing protein. (434 aa)

Your Current Organism:

Culex quinquefasciatus

NCBI taxonomy Id: 7176
Other names: C. quinquefasciatus, Culex fatigans, Culex pipiens fatigans, Culex pipiens quinquefasciatus, southern house mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0W1I3_CULQU	B0WM39_CULQU	B0W1I3	B0WM39	Protein expanded.	Merlin/moesin/ezrin/radixin.	0.933
B0W1I3_CULQU	B0XK08_CULQU	B0W1I3	B0XK08	Protein expanded.	Merlin/moesin/ezrin/radixin.	0.933
B0W2T8_CULQU	B0W379_CULQU	B0W2T8	B0W379	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Sorting nexin, putative.	0.592
B0W2T8_CULQU	B0WM39_CULQU	B0W2T8	B0WM39	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Merlin/moesin/ezrin/radixin.	0.464
B0W2T8_CULQU	B0WNC3_CULQU	B0W2T8	B0WNC3	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Past-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.461
B0W2T8_CULQU	B0WWP0_CULQU	B0W2T8	B0WWP0	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Tyrosine-protein phosphatase non-receptor type 23.	0.799
B0W2T8_CULQU	B0XGX0_CULQU	B0W2T8	B0XGX0	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.533
B0W2T8_CULQU	B0XK08_CULQU	B0W2T8	B0XK08	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Merlin/moesin/ezrin/radixin.	0.464
B0W379_CULQU	B0W2T8_CULQU	B0W379	B0W2T8	Sorting nexin, putative.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.592
B0W379_CULQU	B0WAH8_CULQU	B0W379	B0WAH8	Sorting nexin, putative.	Uncharacterized protein.	0.403
B0W379_CULQU	B0WVY7_CULQU	B0W379	B0WVY7	Sorting nexin, putative.	Vacuolar protein sorting-associated protein 26B-B.	0.979
B0W379_CULQU	B0XGX0_CULQU	B0W379	B0XGX0	Sorting nexin, putative.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.992
B0W3D0_CULQU	B0WAH8_CULQU	B0W3D0	B0WAH8	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Uncharacterized protein.	0.887
B0W3D0_CULQU	B0WC20_CULQU	B0W3D0	B0WC20	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Vacuolar protein sorting.	0.542
B0W3D0_CULQU	B0WEG6_CULQU	B0W3D0	B0WEG6	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.998
B0W3D0_CULQU	B0WI66_CULQU	B0W3D0	B0WI66	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Inhibitor of kappab kinase epsilon.	0.563
B0W3D0_CULQU	B0WK55_CULQU	B0W3D0	B0WK55	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Ras-related protein Rab-8A, putative.	0.898
B0W3D0_CULQU	B0WLA2_CULQU	B0W3D0	B0WLA2	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Exocyst complex component 3.	0.999
B0W3D0_CULQU	B0WNV6_CULQU	B0W3D0	B0WNV6	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Vps53 protein.	0.622
B0W3D0_CULQU	B0WU68_CULQU	B0W3D0	B0WU68	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.	Exocyst complex-subunit protein, 84kD-subunit, putative.	0.999