45 items (Culex quinquefasciatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B0W7C4_CULQU	Plectin-1. (468 aa)
	B0WDS4_CULQU	Spectrin beta chain; Belongs to the spectrin family. (2299 aa)
	B0WD29_CULQU	Uncharacterized protein. (701 aa)
	B0WD28_CULQU	ARF GTPase-activating protein GIT2. (278 aa)
	B0WBF0_CULQU	P21(CDKN1A)-activated kinase 4. (525 aa)
	B0WBE9_CULQU	CRIB domain-containing protein. (339 aa)
	B0WB11_CULQU	E3 ubiquitin-protein ligase. (893 aa)
	B0W8U1_CULQU	Signal transducing adapter molecule 1. (642 aa)
	B0W7C6_CULQU	Kakapo. (7917 aa)
	B0W7C3_CULQU	Kakapo. (124 aa)
	B0W7C2_CULQU	Kakapo. (221 aa)
	B0W7C1_CULQU	Calponin-homology (CH) domain-containing protein. (90 aa)
	B0W702_CULQU	Cytoplasmic protein NCK1. (412 aa)
	B0W4Z9_CULQU	Pak-interacting exchange factor, beta-pix/cool-1. (656 aa)
	B0W3F9_CULQU	Gtpase_rho. (194 aa)
	B0W3F8_CULQU	Uncharacterized protein. (336 aa)
	B0W2T8_CULQU	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (745 aa)
	B0W145_CULQU	Growth factor receptor-bound protein. (190 aa)
	B0W0X0_CULQU	Cdc42 GTPase-activating protein. (136 aa)
	B0XFC9_CULQU	Phosphatidylinositol 3-kinase regulatory subunit. (872 aa)
	B0XAL5_CULQU	Beta chain spectrin. (410 aa)
	B0X9A7_CULQU	Myosin vi; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (785 aa)
	B0X7T1_CULQU	Eph receptor tyrosine kinase. (730 aa)
	B0X7S3_CULQU	CRIB domain-containing protein. (96 aa)
	B0X7B6_CULQU	Beta chain spectrin. (110 aa)
	B0X747_CULQU	Myosin-IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1033 aa)
	B0X6L2_CULQU	Dlg5 protein. (870 aa)
	B0X664_CULQU	Uncharacterized protein. (257 aa)
	B0X640_CULQU	Spectrin alpha chain. (2412 aa)
	B0X5K8_CULQU	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1666 aa)
	B0X483_CULQU	Ubiquitin specific protease 9/faf; Belongs to the peptidase C19 family. (930 aa)
	B0X0X6_CULQU	Beta chain spectrin. (525 aa)
	B0X0V8_CULQU	Beta chain spectrin. (133 aa)
	B0X097_CULQU	Cdc42 GTPase-activating protein. (1273 aa)
	B0WWZ6_CULQU	Phosphatidylinositol 3-kinase regulatory subunit. (841 aa)
	B0WWZ5_CULQU	Uncharacterized protein. (200 aa)
	B0WTP1_CULQU	Vang-like protein. (596 aa)
	B0WQ67_CULQU	Dynamin-associated protein. (1085 aa)
	B0WPT0_CULQU	Uncharacterized protein. (493 aa)
	B0WP09_CULQU	Par-6 gamma. (220 aa)
	B0WP08_CULQU	PB1 domain-containing protein. (101 aa)
	B0WNI1_CULQU	WD_REPEATS_REGION domain-containing protein. (878 aa)
	B0WKV3_CULQU	CRIB domain-containing protein. (97 aa)
	B0WJV4_CULQU	Uncharacterized protein. (232 aa)
	B0WFH2_CULQU	Non-specific serine/threonine protein kinase. (641 aa)

Your Current Organism:

Culex quinquefasciatus

NCBI taxonomy Id: 7176
Other names: C. quinquefasciatus, Culex fatigans, Culex pipiens fatigans, Culex pipiens quinquefasciatus, southern house mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0W0X0_CULQU	B0W145_CULQU	B0W0X0	B0W145	Cdc42 GTPase-activating protein.	Growth factor receptor-bound protein.	0.451
B0W145_CULQU	B0W0X0_CULQU	B0W145	B0W0X0	Growth factor receptor-bound protein.	Cdc42 GTPase-activating protein.	0.451
B0W145_CULQU	B0W2T8_CULQU	B0W145	B0W2T8	Growth factor receptor-bound protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.664
B0W145_CULQU	B0W3F8_CULQU	B0W145	B0W3F8	Growth factor receptor-bound protein.	Uncharacterized protein.	0.446
B0W145_CULQU	B0W3F9_CULQU	B0W145	B0W3F9	Growth factor receptor-bound protein.	Gtpase_rho.	0.446
B0W145_CULQU	B0W4Z9_CULQU	B0W145	B0W4Z9	Growth factor receptor-bound protein.	Pak-interacting exchange factor, beta-pix/cool-1.	0.662
B0W145_CULQU	B0W702_CULQU	B0W145	B0W702	Growth factor receptor-bound protein.	Cytoplasmic protein NCK1.	0.821
B0W145_CULQU	B0W8U1_CULQU	B0W145	B0W8U1	Growth factor receptor-bound protein.	Signal transducing adapter molecule 1.	0.735
B0W145_CULQU	B0WB11_CULQU	B0W145	B0WB11	Growth factor receptor-bound protein.	E3 ubiquitin-protein ligase.	0.614
B0W145_CULQU	B0WBE9_CULQU	B0W145	B0WBE9	Growth factor receptor-bound protein.	CRIB domain-containing protein.	0.498
B0W145_CULQU	B0WBF0_CULQU	B0W145	B0WBF0	Growth factor receptor-bound protein.	P21(CDKN1A)-activated kinase 4.	0.498
B0W145_CULQU	B0WD28_CULQU	B0W145	B0WD28	Growth factor receptor-bound protein.	ARF GTPase-activating protein GIT2.	0.467
B0W145_CULQU	B0WD29_CULQU	B0W145	B0WD29	Growth factor receptor-bound protein.	Uncharacterized protein.	0.467
B0W145_CULQU	B0WFH2_CULQU	B0W145	B0WFH2	Growth factor receptor-bound protein.	Non-specific serine/threonine protein kinase.	0.518
B0W145_CULQU	B0WKV3_CULQU	B0W145	B0WKV3	Growth factor receptor-bound protein.	CRIB domain-containing protein.	0.518
B0W145_CULQU	B0WNI1_CULQU	B0W145	B0WNI1	Growth factor receptor-bound protein.	WD_REPEATS_REGION domain-containing protein.	0.560
B0W145_CULQU	B0WQ67_CULQU	B0W145	B0WQ67	Growth factor receptor-bound protein.	Dynamin-associated protein.	0.629
B0W145_CULQU	B0WWZ5_CULQU	B0W145	B0WWZ5	Growth factor receptor-bound protein.	Uncharacterized protein.	0.845
B0W145_CULQU	B0WWZ6_CULQU	B0W145	B0WWZ6	Growth factor receptor-bound protein.	Phosphatidylinositol 3-kinase regulatory subunit.	0.845
B0W145_CULQU	B0X097_CULQU	B0W145	B0X097	Growth factor receptor-bound protein.	Cdc42 GTPase-activating protein.	0.451