STRINGSTRING
dxr dxr ispF ispF ispD ispD ispE ispE ispH ispH EFM09864.1 EFM09864.1 argR argR EFM09866.1 EFM09866.1 EFM09867.1 EFM09867.1 dxs dxs EFM09869.1 EFM09869.1 xseB xseB xseA xseA nusB nusB EFM09874.1 EFM09874.1 EFM09875.1 EFM09875.1 EFM09876.1 EFM09876.1 ispG ispG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa)
ispF2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (163 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (232 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (284 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (317 aa)
EFM09864.1DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (568 aa)
argRArginine repressor, ArgR; Regulates arginine biosynthesis genes. (152 aa)
EFM09866.1KEGG: pjd:Pjdr2_2314 hypothetical protein. (155 aa)
EFM09867.1TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: pjd:Pjdr2_2313 hemolysin A; SMART: RNA-binding S4 domain protein. (277 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (630 aa)
EFM09869.1PFAM: Polyprenyl synthetase; KEGG: pjd:Pjdr2_2311 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (304 aa)
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (82 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (458 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (156 aa)
EFM09874.1PFAM: Protein of unknown function DUF2273; KEGG: gym:GYMC10_2103 hypothetical protein. (79 aa)
EFM09875.1PFAM: protein of unknown function DUF322; KEGG: pjd:Pjdr2_2305 hypothetical protein. (193 aa)
EFM09876.1PFAM: protein of unknown function DUF322; KEGG: pjd:Pjdr2_2304 protein of unknown function DUF322. (135 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (370 aa)
Your Current Organism:
Paenibacillus curdlanolyticus
NCBI taxonomy Id: 717606
Other names: P. curdlanolyticus YK9, Paenibacillus curdlanolyticus ATCC 51898, Paenibacillus curdlanolyticus DSM 10247, Paenibacillus curdlanolyticus IFO 15724, Paenibacillus curdlanolyticus NBRC 15724, Paenibacillus curdlanolyticus YK9, Paenibacillus curdlanolyticus str. YK9, Paenibacillus curdlanolyticus strain YK9
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