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hemF | Coproporphyrinogen-III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (309 aa) | ||||
ADZ90508.1 | Magnesium chelatase; PFAM: ATPase, AAA-5; KEGG: mmw:Mmwyl1_3380 magnesium chelatase; SMART: ATPase, AAA+ type, core. (600 aa) | ||||
ADZ90509.1 | PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ-like glutamine amidotransferase; KEGG: mmw:Mmwyl1_3379 cobyrinic acid ac-diamide synthase. (451 aa) | ||||
cbiD | cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (367 aa) | ||||
ADZ90511.1 | KEGG: mmw:Mmwyl1_3377 precorrin-6A reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase. (262 aa) | ||||
ADZ90512.1 | KEGG: mmw:Mmwyl1_3376 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core. (223 aa) | ||||
ADZ90513.1 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; KEGG: mmw:Mmwyl1_3375 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole methylase. (423 aa) | ||||
ADZ90514.1 | Precorrin-2 C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; KEGG: mmw:Mmwyl1_3374 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase. (240 aa) | ||||
ADZ90515.1 | PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: mmw:Mmwyl1_3373 cobalamin biosynthesis protein CbiG. (263 aa) | ||||
ADZ90547.1 | precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: mmw:Mmwyl1_1374 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase. (258 aa) | ||||
ADZ90548.1 | Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; KEGG: mmw:Mmwyl1_1375 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase. (258 aa) | ||||
ADZ90550.1 | TIGRFAM: Cobaltochelatase, CobN subunit; KEGG: mmw:Mmwyl1_1377 cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase. (1281 aa) | ||||
ADZ90552.1 | Sirohydrochlorin ferrochelatase; KEGG: mmw:Mmwyl1_1378 cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiX. (420 aa) | ||||
ADZ90625.1 | TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; KEGG: mmw:Mmwyl1_3251 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Belongs to the precorrin methyltransferase family. (247 aa) | ||||
ADZ91187.1 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (202 aa) | ||||
hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (332 aa) | ||||
ADZ91399.1 | PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; KEGG: mmw:Mmwyl1_2220 cobalamin (vitamin B12) biosynthesis CbiX protein. (125 aa) | ||||
ADZ91413.1 | TIGRFAM: Oxygen-independent coproporphyrinogen III oxidase HemN; PFAM: HemN, C-terminal; Radical SAM; KEGG: mmw:Mmwyl1_2234 oxygen-independent coproporphyrinogen III oxidase; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (456 aa) | ||||
hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (308 aa) | ||||
ADZ92176.1 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (260 aa) | ||||
ADZ92177.1 | hemX domain protein; PFAM: HemX; KEGG: mmw:Mmwyl1_3593 hypothetical protein. (453 aa) | ||||
ADZ92178.1 | HemY domain protein; PFAM: HemY, N-terminal; KEGG: mmw:Mmwyl1_3594 HemY domain-containing protein. (413 aa) | ||||
hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (439 aa) | ||||
ADZ92361.1 | TIGRFAM: Cob(II)yrinic acid a,c-diamide reductase; KEGG: mmw:Mmwyl1_1437 cob(II)yrinic acid a,c-diamide reductase; PFAM: Nitroreductase-like. (214 aa) | ||||
ADZ92377.1 | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (204 aa) | ||||
ADZ92379.1 | KEGG: mmw:Mmwyl1_1411 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1. (201 aa) | ||||
cobS | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (259 aa) | ||||
cobT | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (355 aa) | ||||
hemL | Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; KEGG: mmw:Mmwyl1_1328 glutamate-1-semialdehyde-2,1-aminomutase. (427 aa) | ||||
ADZ92406.1 | KEGG: hch:HCH_06247 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00701; PFAM: Uncharacterised protein family UPF0093. (140 aa) | ||||
hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (366 aa) | ||||
ADZ92669.1 | Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (182 aa) | ||||
ADZ92670.1 | PFAM: Aminotransferase, class I/classII; KEGG: mmw:Mmwyl1_3676 class I/II aminotransferase. (372 aa) | ||||
cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (313 aa) | ||||
cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (497 aa) | ||||
ADZ92681.1 | Porphobilinogen synthase; KEGG: mmw:Mmwyl1_3998 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family. (330 aa) |