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| | bamA | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (769 aa) |
| | ADZ90428.1 | KEGG: mmw:Mmwyl1_1281 outer membrane chaperone Skp (OmpH); PFAM: Outer membrane chaperone Skp (OmpH); SMART: Outer membrane chaperone Skp (OmpH). (164 aa) |
| | ADZ90455.1 | PFAM: Protein of unknown function DUF368; KEGG: mmw:Mmwyl1_1306 hypothetical protein. (304 aa) |
| | ADZ90483.1 | FeS assembly protein SufB; KEGG: mmw:Mmwyl1_1344 cysteine desulfurase activator complex subunit SufB; TIGRFAM: SUF system FeS cluster assembly, SufB; PFAM: SUF system FeS cluster assembly, SufBD. (478 aa) |
| | ADZ90484.1 | TIGRFAM: ATPase SufC, SUF system FeS cluster assembly; PFAM: ABC transporter-like; KEGG: mmw:Mmwyl1_1345 FeS assembly ATPase SufC; SMART: ATPase, AAA+ type, core. (261 aa) |
| | ADZ90485.1 | KEGG: mmw:Mmwyl1_1346 FeS assembly protein SufD; TIGRFAM: SUF system FeS cluster assembly, SufD; PFAM: SUF system FeS cluster assembly, SufBD. (425 aa) |
| | ADZ90487.1 | KEGG: mmw:Mmwyl1_1348 iron-sulfur cluster assembly accessory protein; TIGRFAM: FeS cluster insertion; PFAM: FeS cluster biogenesis; Belongs to the HesB/IscA family. (117 aa) |
| | ADZ90488.1 | KEGG: mmw:Mmwyl1_1349 hypothetical protein; TIGRFAM: FeS assembly SUF system protein SufT, putative; PFAM: Domain of unknown function DUF59. (173 aa) |
| | ADZ90489.1 | PFAM: Fe-S metabolism associated SufE; KEGG: mmw:Mmwyl1_1350 Fe-S metabolism associated SufE. (141 aa) |
| | ADZ90490.1 | Cysteine desulfurase; KEGG: mmw:Mmwyl1_1351 class V aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase. (383 aa) |
| | bamB | Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (376 aa) |
| | ADZ90602.1 | SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: mmw:Mmwyl1_3275 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim domain. (673 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (881 aa) |
| | rsfS | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (112 aa) |
| | mrdA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (624 aa) |
| | mrdB | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (373 aa) |
| | rlpA | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (305 aa) |
| | ADZ90746.1 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. (382 aa) |
| | parC | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (756 aa) |
| | ADZ90847.1 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; KEGG: gpb:HDN1F_04020 ATP-dependent DNA helicase; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal. (706 aa) |
| | lptA | Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (172 aa) |
| | ADZ91034.1 | Protein of unknown function DUF1239; PFAM: Lipopolysccharide assembly, LptC-related; KEGG: mmw:Mmwyl1_2415 hypothetical protein. (195 aa) |
| | ADZ91036.1 | Fe(3+)-transporting ATPase; PFAM: ABC transporter-like; KEGG: mmw:Mmwyl1_2413 ABC transporter-like protein; SMART: ATPase, AAA+ type, core. (267 aa) |
| | ADZ91039.1 | PFAM: Toluene tolerance Ttg2; KEGG: mmw:Mmwyl1_2410 toluene tolerance family protein. (204 aa) |
| | ADZ91041.1 | PFAM: BolA protein; KEGG: mmw:Mmwyl1_2409 BolA family protein; Belongs to the BolA/IbaG family. (78 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa) |
| | ADZ91059.1 | PFAM: VacJ-like lipoprotein; KEGG: mmw:Mmwyl1_2518 VacJ family lipoprotein. (280 aa) |
| | ADZ91141.1 | PFAM: DNA helicase, UvrD/REP type; KEGG: mmw:Mmwyl1_2436 UvrD/REP helicase. (779 aa) |
| | ADZ91152.1 | PFAM: NADPH-dependent FMN reductase; KEGG: gpb:HDN1F_31140 NADPH-dependent FMN reductase. (188 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (199 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (338 aa) |
| | cpoB | Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (270 aa) |
| | ADZ91232.1 | KEGG: mmw:Mmwyl1_2144 hypothetical protein. (364 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (337 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (276 aa) |
| | ADZ91302.1 | KEGG: mmw:Mmwyl1_2168 hypothetical protein. (668 aa) |
| | fliQ | Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa) |
| | ADZ92437.1 | Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (260 aa) |
| | flhA | Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (708 aa) |
| | ADZ92434.1 | Flagellar biosynthetic protein FlhF; TIGRFAM: Signal-recognition particle (SRP)-type GTPase; PFAM: Signal recognition particle, SRP54 subunit, GTPase; KEGG: mmw:Mmwyl1_3429 GTP-binding signal recognition particle; SMART: Signal recognition particle, SRP54 subunit, GTPase; ATPase, AAA+ type, core. (432 aa) |
| | ADZ92421.1 | KEGG: mmw:Mmwyl1_3416 hypothetical protein. (612 aa) |
| | ccmA | Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (200 aa) |
| | ADZ92419.1 | Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (220 aa) |
| | ccmC | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (247 aa) |
| | ADZ92417.1 | KEGG: mmw:Mmwyl1_3410 cytochrome c-type biogenesis protein CcmF; TIGRFAM: Cytochrome c-type biogenesis protein CcmF; PFAM: Cytochrome c assembly protein. (646 aa) |
| | ADZ92416.1 | KEGG: mmw:Mmwyl1_3409 periplasmic protein thiol--disulphide oxidoreductase DsbE; TIGRFAM: Periplasmic protein thiol:disulphide oxidoreductase DsbE; PFAM: Redoxin. (169 aa) |
| | ADZ92415.1 | Cytochrome C biogenesis protein; Possible subunit of a heme lyase. (142 aa) |
| | ADZ92414.1 | PFAM: Tetratricopeptide TPR2; KEGG: mmw:Mmwyl1_3407 TPR repeat-containing protein. (370 aa) |
| | zipA | Cell division protein zipA-like protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (351 aa) |
| | ADZ92341.1 | Pectinesterase; KEGG: mmw:Mmwyl1_0740 pectinesterase; PFAM: Pectinesterase, catalytic. (341 aa) |
| | ADZ92335.1 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (77 aa) |
| | ADZ92305.1 | Protein-disulfide reductase; KEGG: mmw:Mmwyl1_2980 cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane domain; Thioredoxin domain. (638 aa) |
| | ADZ92273.1 | KEGG: pca:Pcar_2830 hypothetical protein. (1385 aa) |
| | ADZ92271.1 | Hypothetical protein. (97 aa) |
| | ADZ92269.1 | Hypothetical protein. (114 aa) |
| | lptE | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. (178 aa) |
| | rapA | SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (940 aa) |
| | bamD | Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (280 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (362 aa) |
| | ADZ92157.1 | Protein-disulfide reductase; KEGG: mmw:Mmwyl1_2329 cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane domain; Thioredoxin domain. (620 aa) |
| | ADZ92132.1 | ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (355 aa) |
| | recC | Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (1155 aa) |
| | recB | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] (1233 aa) |
| | recD | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] (672 aa) |
| | ADZ91984.1 | KEGG: bge:BC1002_0442 protein of unknown function DUF37; manually curated; PFAM: Protein of unknown function DUF37. (67 aa) |
| | ADZ91896.1 | Hypothetical protein. (233 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1136 aa) |
| | ADZ91806.1 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa) |
| | ftsI | Penicillin-binding protein transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (586 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (496 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (452 aa) |
| | mraY | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (449 aa) |
| | ftsW | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (406 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (357 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (476 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (315 aa) |
| | ftsQ | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (229 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (413 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | minC | Septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (251 aa) |
| | ADZ91564.1 | KEGG: mmw:Mmwyl1_2353 septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase. (289 aa) |
| | nfuA | Fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (193 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (342 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (876 aa) |
| | ADZ91414.1 | KEGG: mmw:Mmwyl1_2235 putative hydrolase protein. (195 aa) |
| | ADZ91407.1 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; RQC domain; KEGG: mmw:Mmwyl1_2228 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; RQC domain. (575 aa) |
| | ADZ91397.1 | PFAM: DNA topoisomerase, type IA, zn finger; KEGG: mmw:Mmwyl1_2218 DNA topoisomerase type IA Zn finger domain-containing protein. (167 aa) |
| | ADZ92538.1 | KEGG: mmw:Mmwyl1_2686 CRISPR-associated Csy4 family protein; TIGRFAM: CRISPR-associated protein Csy4; PFAM: CRISPR-associated protein Csy4. (201 aa) |
| | ADZ92512.1 | KEGG: mmw:Mmwyl1_3496 lysozyme subfamily protein. (351 aa) |
| | ADZ92472.1 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (457 aa) |
| | ADZ92851.1 | PFAM: Protein of unknown function DUF1566; KEGG: sde:Sde_1186 hypothetical protein. (190 aa) |
| | ADZ92452.1 | PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; KEGG: mmw:Mmwyl1_3446 flagellar assembly protein FliH. (265 aa) |
| | ADZ92450.1 | KEGG: mmw:Mmwyl1_3444 flagellar export protein FliJ; TIGRFAM: Flagellar export FliJ; PFAM: Flagellar export FliJ. (145 aa) |
| | ADZ92445.1 | PFAM: Flagellar hook-length control protein-like, C-terminal domain; KEGG: mmw:Mmwyl1_3439 flagellar hook-length control protein. (652 aa) |
| | ADZ92440.1 | KEGG: mmw:Mmwyl1_3435 flagellar biosynthesis protein FliO; TIGRFAM: Flagellar biosynthesis protein, FliO; PFAM: Flagellar biosynthesis protein, FliO. (128 aa) |
| | fliP | Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (251 aa) |
| | ADZ92695.1 | KEGG: mmw:Mmwyl1_0738 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal. (606 aa) |
| | engB | GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (212 aa) |
| | ADZ92649.1 | Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein; PFAM: Magnesium chelatase, ChlI subunit; KEGG: mmw:Mmwyl1_3653 Mg chelatase subunit ChlI; SMART: ATPase, AAA+ type, core. (505 aa) |
| | rep | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (682 aa) |
| | ADZ92582.1 | Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein. (236 aa) |
| | ADZ92581.1 | KEGG: mmw:Mmwyl1_3580 hypothetical protein; TIGRFAM: flagellar hook-basal body protein, FlgE/F/G; PFAM: Flagellar basal body FlaE; Flagellar basal body rod protein, N-terminal; Domain of unknown function DUF1078, C-terminal. (565 aa) |
| | ADZ92576.1 | Flagellar rod assembly protein/muramidase FlgJ; TIGRFAM: Flagellar protein FlgJ type-2; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; Flagellar protein FlgJ, N-terminal; KEGG: mmw:Mmwyl1_3575 flagellar rod assembly protein/muramidase FlgJ; SMART: Lysozyme domain, subfamily 2. (338 aa) |
| | ADZ92575.1 | KEGG: mmw:Mmwyl1_3574 flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK; PFAM: Domain of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; Belongs to the flagella basal body rod proteins family. (659 aa) |
| | ADZ92568.1 | KEGG: mmw:Mmwyl1_3567 flagellar protein FliS; TIGRFAM: Flagellar protein FliS; PFAM: Flagellar protein FliS. (140 aa) |
| | parE | DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (632 aa) |
| | cas1-2 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (325 aa) |
| | ADZ92852.1 | PFAM: Protein of unknown function DUF1566; KEGG: shw:Sputw3181_0674 hypothetical protein. (420 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (743 aa) |
| | ADZ93008.1 | KEGG: hau:Haur_1680 NERD domain-containing protein; PFAM: NERD; SMART: DEAD-like helicase, N-terminal. (797 aa) |
| | ADZ93133.1 | Scramblase family protein; PFAM: Scramblase; KEGG: meh:M301_2135 scramblase family protein. (194 aa) |
| | ADZ93151.1 | KEGG: mgm:Mmc1_2519 putative esterase. (242 aa) |
| | ADZ93157.1 | KEGG: pca:Pcar_0899 hypothetical protein. (652 aa) |
| | ADZ93197.1 | PFAM: Peptide chain release factor class I/class II; KEGG: mmw:Mmwyl1_1495 class I peptide chain release factor. (138 aa) |
| | ADZ93309.1 | PFAM: Peptidase A24A, prepilin type IV; KEGG: mmw:Mmwyl1_0304 peptidase A24A prepilin type IV. (182 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | ADZ93377.1 | PFAM: DNA helicase, UvrD/REP type; KEGG: mmw:Mmwyl1_4444 UvrD/REP helicase. (736 aa) |
| | ADZ93387.1 | PFAM: Fe-S metabolism associated SufE; KEGG: mmw:Mmwyl1_4451 Fe-S metabolism associated SufE. (134 aa) |
| | secB | Protein-export protein secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (158 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (807 aa) |
| | ADZ89348.1 | KEGG: psm:PSM_A2311 hypothetical protein. (1004 aa) |
| | ADZ89349.1 | KEGG: spl:Spea_0612 hypothetical protein. (274 aa) |
| | ADZ89391.1 | KEGG: tsi:TSIB_0432 hypothetical protein. (293 aa) |
| | ureE | Urease accessory protein ureE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (154 aa) |
| | ADZ89457.1 | PFAM: NADPH-dependent FMN reductase; KEGG: sse:Ssed_3574 hypothetical protein. (177 aa) |
| | murJ | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (549 aa) |
| | ADZ89755.1 | KEGG: mmw:Mmwyl1_4085 MltA domain-containing protein; PFAM: Lytic transglycosylase MltA; 3D; SMART: Lytic transglycosylase MltA. (370 aa) |
| | bamE | SmpA/OmlA domain-containing protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (105 aa) |
| | glmU | Bifunctional protein glmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (455 aa) |
| | cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (92 aa) |
| | ADZ89967.1 | PFAM: Cytochrome c assembly protein; KEGG: mmw:Mmwyl1_3772 cytochrome c assembly protein. (255 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | erpA | Iron--sulfur cluster insertion protein erpA; Required for insertion of 4Fe-4S clusters for at least IspG. (113 aa) |
| | ADZ90246.1 | Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mmw:Mmwyl1_1018 hypothetical protein. (100 aa) |
| | ADZ90272.1 | Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (97 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (364 aa) |
| | surA | Chaperone surA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (419 aa) |
| | lptD | Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (753 aa) |
| | ADZ90306.1 | FlgN family protein; PFAM: FlgN-like domain; KEGG: mmw:Mmwyl1_1065 FlgN family protein. (158 aa) |
| | ADZ90307.1 | KEGG: mmw:Mmwyl1_1066 anti-sigma-28 factor, FlgM; TIGRFAM: Anti-sigma-28 factor, FlgM; PFAM: Anti-sigma-28 factor, FlgM. (105 aa) |
| | ADZ90308.1 | Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (231 aa) |
| | ADZ90367.1 | Peptidoglycan glycosyltransferase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (778 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa) |
| | frr | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | uppS | Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (242 aa) |
