STRINGSTRING
ADZ89573.1 ADZ89573.1 purK purK ADZ90109.1 ADZ90109.1 ADZ90110.1 ADZ90110.1 ADZ90288.1 ADZ90288.1 trpC trpC ADZ90317.1 ADZ90317.1 ADZ90327.1 ADZ90327.1 ppc ppc panD panD moaA moaA ADZ90541.1 ADZ90541.1 ADZ90591.1 ADZ90591.1 ADZ90685.1 ADZ90685.1 ADZ90751.1 ADZ90751.1 ADZ90859.1 ADZ90859.1 thiC thiC ADZ91340.1 ADZ91340.1 ADZ92940.1 ADZ92940.1 cobD cobD ADZ92670.1 ADZ92670.1 hemE hemE pckA pckA lysA lysA ADZ92105.1 ADZ92105.1 pyrF pyrF ADZ91967.1 ADZ91967.1 ADZ91823.1 ADZ91823.1 psd psd ADZ91535.1 ADZ91535.1 ADZ91454.1 ADZ91454.1 ADZ91377.1 ADZ91377.1 ADZ91364.1 ADZ91364.1 ubiC ubiC ADZ93294.1 ADZ93294.1 ADZ93220.1 ADZ93220.1 ADZ93014.1 ADZ93014.1 ADZ89346.1 ADZ89346.1 ADZ89748.1 ADZ89748.1 ribB ribB ADZ89805.1 ADZ89805.1 oadG oadG ADZ90038.1 ADZ90038.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADZ89573.1PFAM: Pyruvate carboxyltransferase; KEGG: mab:MAB_3553 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (407 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. (355 aa)
ADZ90109.1PFAM: Amidohydrolase 2; KEGG: mmw:Mmwyl1_3943 amidohydrolase 2. (334 aa)
ADZ90110.1KEGG: mmw:Mmwyl1_3942 hypothetical protein; TIGRFAM: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; PFAM: Ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase. (225 aa)
ADZ90288.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa)
trpCKEGG: mmw:Mmwyl1_1063 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (270 aa)
ADZ90317.1TIGRFAM: KDPG/KHG aldolase; KEGG: mmw:Mmwyl1_1039 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG/KHG aldolase. (207 aa)
ADZ90327.1KEGG: mmw:Mmwyl1_1152 deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase, FAD-binding/Cryptochrome, C-terminal; DNA photolyase, N-terminal. (497 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (876 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (331 aa)
ADZ90541.1KEGG: cti:RALTA_B0267 isocitrate lyase; PFAM: Isocitrate lyase/phosphorylmutase. (530 aa)
ADZ90591.1KEGG: saz:Sama_1962 adenosylmethionine decarboxylase; PFAM: S-adenosylmethionine decarboxylase. (309 aa)
ADZ90685.1KEGG: mmw:Mmwyl1_0212 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: KDPG/KHG aldolase; PFAM: KDPG/KHG aldolase. (217 aa)
ADZ90751.1Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (630 aa)
ADZ90859.1KEGG: mmw:Mmwyl1_3120 ribulose-bisphosphate carboxylase; PFAM: Ribulose bisphosphate carboxylase, large subunit, C-terminal; Belongs to the RuBisCO large chain family. (406 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (649 aa)
ADZ91340.1Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (162 aa)
ADZ92940.1Malic protein NAD-binding protein; KEGG: mmw:Mmwyl1_4123 malate dehydrogenase; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SMART: Malic enzyme, NAD-binding. (422 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (313 aa)
ADZ92670.1PFAM: Aminotransferase, class I/classII; KEGG: mmw:Mmwyl1_3676 class I/II aminotransferase. (372 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (366 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (518 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (417 aa)
ADZ92105.1Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily. (287 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa)
ADZ91967.1KEGG: mmw:Mmwyl1_1637 histidine decarboxylase; PFAM: Pyridoxal phosphate-dependent decarboxylase. (383 aa)
ADZ91823.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa)
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (285 aa)
ADZ91535.1TIGRFAM: Aminodeoxychorismate lyase, class IV; KEGG: mmw:Mmwyl1_2269 class IV aminotransferase; PFAM: Aminotransferase, class IV. (291 aa)
ADZ91454.1KEGG: cja:CJA_2967 hydroxymethylglutaryl-CoA lyase, (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase); PFAM: Pyruvate carboxyltransferase. (299 aa)
ADZ91377.1KEGG: ppr:PBPRB0466 fructose-1,6-bisphosphate aldolase; PFAM: Ketose-bisphosphate aldolase, class-II. (280 aa)
ADZ91364.1Tyrosine decarboxylase; KEGG: aca:ACP_2295 pyridoxal-dependent decarboxylase conserved domain protein; PFAM: Pyridoxal phosphate-dependent decarboxylase. (464 aa)
ubiCChorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (179 aa)
ADZ93294.1KEGG: hau:Haur_3957 hypothetical protein. (209 aa)
ADZ93220.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (355 aa)
ADZ93014.1OHCU decarboxylase; KEGG: mmw:Mmwyl1_2708 hypothetical protein; TIGRFAM: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (177 aa)
ADZ89346.1KEGG: mmw:Mmwyl1_0053 dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase; Belongs to the DapA family. (320 aa)
ADZ89748.1Cryptochrome, DASH family; KEGG: mmw:Mmwyl1_0336 cryptochrome DASH; TIGRFAM: Cryptochrome, DASH; PFAM: DNA photolyase, FAD-binding/Cryptochrome, C-terminal; DNA photolyase, N-terminal. (458 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (384 aa)
ADZ89805.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (406 aa)
oadGSodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (81 aa)
ADZ90038.1TIGRFAM: Oxaloacetate decarboxylase, alpha subunit; KEGG: mmw:Mmwyl1_3623 oxaloacetate decarboxylase; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; Biotin/lipoyl attachment. (594 aa)
Your Current Organism:
Marinomonas mediterranea
NCBI taxonomy Id: 717774
Other names: M. mediterranea MMB-1, Marinomonas mediterranea MMB-1, Marinomonas mediterranea str. MMB-1, Marinomonas mediterranea strain MMB-1
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