STRINGSTRING
ADZ93368.1 ADZ93368.1 ADZ89315.1 ADZ89315.1 ADZ89365.1 ADZ89365.1 aroE aroE ADZ89718.1 ADZ89718.1 ADZ89719.1 ADZ89719.1 ADZ89974.1 ADZ89974.1 ADZ90034.1 ADZ90034.1 ADZ90086.1 ADZ90086.1 aroQ aroQ ADZ90143.1 ADZ90143.1 ADZ90248.1 ADZ90248.1 dapB dapB ADZ90288.1 ADZ90288.1 ppc ppc dapE dapE dapD dapD ADZ90691.1 ADZ90691.1 ADZ90732.1 ADZ90732.1 ADZ90733.1 ADZ90733.1 ADZ90808.1 ADZ90808.1 dapF dapF aroA aroA ADZ91226.1 ADZ91226.1 dapA dapA ADZ91324.1 ADZ91324.1 ADZ91368.1 ADZ91368.1 aroC aroC asd asd ADZ91535.1 ADZ91535.1 ADZ91554.1 ADZ91554.1 ADZ91678.1 ADZ91678.1 ADZ91679.1 ADZ91679.1 ADZ91855.1 ADZ91855.1 ADZ91927.1 ADZ91927.1 ADZ92070.1 ADZ92070.1 ADZ92105.1 ADZ92105.1 dapF-2 dapF-2 lysA lysA dapA-2 dapA-2 ADZ92561.1 ADZ92561.1 astE astE ADZ92601.1 ADZ92601.1 fumC fumC ADZ92662.1 ADZ92662.1 ADZ92663.1 ADZ92663.1 astD astD astB astB ADZ92719.1 ADZ92719.1 hutU hutU hutH hutH hutI hutI ADZ92821.1 ADZ92821.1 aroB aroB aroK aroK ADZ92940.1 ADZ92940.1 ADZ92948.1 ADZ92948.1 ADZ93367.1 ADZ93367.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ADZ93368.1KEGG: mmw:Mmwyl1_4429 delta-1-pyrroline-5-carboxylate dehydrogenase. (228 aa)
ADZ89315.1PFAM: Bacterial lipid A biosynthesis acyltransferase; KEGG: cja:CJA_0060 Uvs111. (300 aa)
ADZ89365.1KEGG: csa:Csal_2487 5-dehydro-4-deoxyglucarate dehydratase; PFAM: Dihydrodipicolinate synthetase; Belongs to the DapA family. (302 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (266 aa)
ADZ89718.1KEGG: mmw:Mmwyl1_4114 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. (1483 aa)
ADZ89719.1TIGRFAM: Glutamate synthase, NADH/NADPH, small subunit 2; KEGG: mmw:Mmwyl1_4113 glutamate synthase small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (473 aa)
ADZ89974.1KEGG: mmw:Mmwyl1_3765 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT. (453 aa)
ADZ90034.1KEGG: mmw:Mmwyl1_3627 aspartate kinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family. (413 aa)
ADZ90086.1Peptidase dimerization domain protein; PFAM: Peptidase M20, dimerisation; Peptidase M20; KEGG: mmw:Mmwyl1_3818 peptidase dimerisation domain-containing protein. (409 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa)
ADZ90143.1PFAM: Protein of unknown function DUF339; KEGG: mmw:Mmwyl1_1095 hypothetical protein. (91 aa)
ADZ90248.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (277 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (266 aa)
ADZ90288.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (876 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (388 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (345 aa)
ADZ90691.1PFAM: Shikimate dehydrogenase substrate binding, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; KEGG: mmw:Mmwyl1_3919 shikimate dehydrogenase substrate-binding subunit. (284 aa)
ADZ90732.1Chorismate mutase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; KEGG: mmw:Mmwyl1_2858 chorismate mutase; SMART: Chorismate mutase. (372 aa)
ADZ90733.1KEGG: mmw:Mmwyl1_2857 bifunctional cyclohexadienyl dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: Prephenate dehydrogenase; Enolpyruvate transferase domain. (738 aa)
ADZ90808.1HAMAP: Fumarate hydratase, class II; KEGG: mmw:Mmwyl1_2652 aspartate ammonia-lyase; PFAM: Lyase 1, N-terminal; Fumarase C, C-terminal. (490 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (276 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (425 aa)
ADZ91226.1Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (348 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
ADZ91324.1FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; KEGG: mmw:Mmwyl1_2045 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; Belongs to the folylpolyglutamate synthase family. (410 aa)
ADZ91368.1PFAM: Amidohydrolase 1; KEGG: jan:Jann_2275 amidohydrolase. (417 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (372 aa)
ADZ91535.1TIGRFAM: Aminodeoxychorismate lyase, class IV; KEGG: mmw:Mmwyl1_2269 class IV aminotransferase; PFAM: Aminotransferase, class IV. (291 aa)
ADZ91554.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (358 aa)
ADZ91678.1Glutamate synthase (NADPH); KEGG: tcx:Tcr_1344 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Belongs to the glutamate synthase family. (441 aa)
ADZ91679.1PFAM: Glutamate synthase, alpha subunit, C-terminal; KEGG: psp:PSPPH_2914 FwdC/FmdC family protein. (227 aa)
ADZ91855.1TIGRFAM: Chorismate mutase, periplasmic; PFAM: Chorismate mutase, type II; KEGG: swd:Swoo_3147 chorismate mutase; SMART: Chorismate mutase. (177 aa)
ADZ91927.1Agmatinase; TIGRFAM: Putative agmatinase; KEGG: kpu:KP1_4232 putative arginase/agmatinase/formiminoglutamase; PFAM: Ureohydrolase; Belongs to the arginase family. (318 aa)
ADZ92070.1PFAM: Bacterial lipid A biosynthesis acyltransferase; KEGG: mmw:Mmwyl1_1693 lipid A biosynthesis acyltransferase. (306 aa)
ADZ92105.1Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily. (287 aa)
dapF-2Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (417 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa)
ADZ92561.1TIGRFAM: Sialic acid O-acyltransferase, NeuD; KEGG: spl:Spea_0050 sialic acid biosynthesis protein NeuD. (219 aa)
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (359 aa)
ADZ92601.1PFAM: Bacterial NAD-glutamate dehydrogenase; KEGG: mmw:Mmwyl1_1110 NAD-glutamate dehydrogenase. (1607 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)
ADZ92662.1Arginine/ornithine succinyltransferase subunit; TIGRFAM: Arginine N-succinyltransferase Ast/AOST; KEGG: mmw:Mmwyl1_3668 arginine N-succinyltransferase; PFAM: Arginine N-succinyltransferase Ast/AOST. (343 aa)
ADZ92663.1TIGRFAM: Arginine N-succinyltransferase AstA; Arginine N-succinyltransferase Ast/AOST; KEGG: mmw:Mmwyl1_3669 arginine N-succinyltransferase; PFAM: Arginine N-succinyltransferase Ast/AOST. (347 aa)
astDN-succinylglutamate 5-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (492 aa)
astBN-succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (449 aa)
ADZ92719.1Glutamate synthase (NADPH); KEGG: swd:Swoo_1841 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Belongs to the glutamate synthase family. (547 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (556 aa)
hutHPFAM: Phenylalanine/histidine ammonia-lyase; TIGRFAM: Histidine ammonia-lyase; HAMAP: Histidine ammonia-lyase; KEGG: mmw:Mmwyl1_3901 histidine ammonia-lyase. (510 aa)
hutIImidazolonepropionase; PFAM: Amidohydrolase 1; TIGRFAM: Imidazolonepropionase; HAMAP: Imidazolonepropionase; KEGG: mmw:Mmwyl1_3900 imidazolonepropionase. (409 aa)
ADZ92821.1TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: mmw:Mmwyl1_4015 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. (163 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (365 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (182 aa)
ADZ92940.1Malic protein NAD-binding protein; KEGG: mmw:Mmwyl1_4123 malate dehydrogenase; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SMART: Malic enzyme, NAD-binding. (422 aa)
ADZ92948.1KEGG: mmw:Mmwyl1_4131 hypothetical protein. (208 aa)
ADZ93367.1Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1040 aa)
Your Current Organism:
Marinomonas mediterranea
NCBI taxonomy Id: 717774
Other names: M. mediterranea MMB-1, Marinomonas mediterranea MMB-1, Marinomonas mediterranea str. MMB-1, Marinomonas mediterranea strain MMB-1
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