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| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa) |
| | rimP | Uncharacterized protein conserved in bacteria; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (155 aa) |
| | AL1_00870 | Xylose isomerase-like TIM barrel. (286 aa) |
| | AL1_00980 | Dioxygenases related to 2-nitropropane dioxygenase. (359 aa) |
| | AL1_01080 | Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (169 aa) |
| | engB | Ribosome biogenesis GTP-binding protein YsxC/EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (198 aa) |
| | AL1_02050 | Diaminopimelate decarboxylase. (464 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | AL1_02350 | Dihydropteroate synthase. (271 aa) |
| | AL1_02500 | Hypothetical protein. (291 aa) |
| | AL1_02520 | Hypothetical protein. (129 aa) |
| | AL1_02720 | Sugar kinases, ribokinase family. (348 aa) |
| | AL1_02750 | Sugar kinases, ribokinase family. (330 aa) |
| | AL1_02860 | Pseudouridine synthase family; Belongs to the pseudouridine synthase RsuA family. (455 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (674 aa) |
| | AL1_03080 | 6-phosphofructokinase. (411 aa) |
| | AL1_03190 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. (471 aa) |
| | AL1_04010 | Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1. (245 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (202 aa) |
| | AL1_04450 | ybaK/ebsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (163 aa) |
| | AL1_04460 | dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (352 aa) |
| | AL1_04480 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (187 aa) |
| | AL1_04490 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (294 aa) |
| | AL1_04530 | Carboxynorspermidine dehydrogenase. (396 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa) |
| | glmS | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (614 aa) |
| | AL1_05130 | Uridine phosphorylase. (292 aa) |
| | AL1_05290 | Shikimate dehydrogenase. (245 aa) |
| | AL1_05770 | Flavodoxins. (184 aa) |
| | miaA | tRNA isopentenyltransferase (miaA); Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (301 aa) |
| | AL1_06580 | Fructose-bisphosphate aldolase. (350 aa) |
| | AL1_06940 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa) |
| | AL1_06960 | Conserved hypothetical protein TIGR00255. (286 aa) |
| | AL1_07480 | HipA-like C-terminal domain./HipA-like N-terminal domain. (313 aa) |
| | AL1_07490 | HipA N-terminal domain. (110 aa) |
| | AL1_07970 | Sugar phosphate isomerases/epimerases. (288 aa) |
| | AL1_08080 | [Acyl-carrier-protein] S-malonyltransferase. (293 aa) |
| | nagB | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (266 aa) |
| | AL1_08130 | 6-phosphogluconolactonase/Glucosamine-6- phosphateisomerase/deaminase. (649 aa) |
| | AL1_08260 | Mannose-6-phosphate isomerase, type 1. (321 aa) |
| | cutC | Uncharacterized protein involved in copper resistance; Participates in the control of copper homeostasis. Belongs to the CutC family. (243 aa) |
| | AL1_32200 | Sugar phosphate isomerases/epimerases. (283 aa) |
| | AL1_10420 | Formate acetyltransferase 1. (742 aa) |
| | AL1_10540 | 7-keto-8-aminopelargonate synthetase and related enzymes. (423 aa) |
| | AL1_10610 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0246 family. (253 aa) |
| | rpsO | SSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (90 aa) |
| | AL1_10900 | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (397 aa) |
| | trmH | rRNA methylases; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (243 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (494 aa) |
| | AL1_11110 | Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family. (464 aa) |
| | AL1_11570 | rRNA methylases. (178 aa) |
| | panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (254 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (508 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (228 aa) |
| | AL1_11910 | Predicted redox protein, regulator of disulfide bond formation. (127 aa) |
| | AL1_12290 | Aminoacyl-histidine dipeptidase. (485 aa) |
| | AL1_12360 | Catalase; Belongs to the catalase family. (497 aa) |
| | AL1_12440 | Hypothetical protein. (150 aa) |
| | AL1_12470 | ORF6N domain. (179 aa) |
| | AL1_13100 | 3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (415 aa) |
| | glyQS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (514 aa) |
| | def-2 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (181 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (399 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (187 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (325 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (414 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase, bacterial; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (281 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (142 aa) |
| | AL1_14090 | Phosphotransacetylase. (302 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (364 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (539 aa) |
| | AL1_14250 | SAM-dependent methyltransferase. (399 aa) |
| | cmk | Cytidylate kinase. (233 aa) |
| | ispH | (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (294 aa) |
| | AL1_14960 | Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (298 aa) |
| | AL1_14980 | Uracil phosphoribosyltransferase. (218 aa) |
| | rlmN | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (342 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (376 aa) |
| | AL1_15100 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (361 aa) |
| | AL1_15310 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family. (181 aa) |
| | kbl | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa) |
| | AL1_15540 | Heat shock protein Hsp15. (131 aa) |
| | rsmH | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (300 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (958 aa) |
| | AL1_16120 | Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (334 aa) |
| | folE | GTP cyclohydrolase I. (202 aa) |
| | AL1_16170 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (193 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (293 aa) |
| | AL1_16990 | 23S rRNA m(5)U-1939 methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (469 aa) |
| | AL1_17020 | Cytidine deaminase. (151 aa) |
| | AL1_17030 | Ribosomal large subunit pseudouridine synthase D. (228 aa) |
| | AL1_17270 | Glycogen synthase (UDP-glucose). (268 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (336 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (238 aa) |
| | AL1_17570 | Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (376 aa) |
| | AL1_17690 | O(6)-alkylguanine repair protein YbaZ. (100 aa) |
| | prfA | Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (361 aa) |
| | rpsG | SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (158 aa) |
| | rpsC | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (262 aa) |
| | rpsQ | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rplE | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (167 aa) |
| | AL1_17940 | SSU ribosomal protein S8P; Belongs to the universal ribosomal protein uS8 family. (99 aa) |
| | rpsE | SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (172 aa) |
| | rplO | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa) |
| | AL1_18090 | Acyl dehydratase. (154 aa) |
| | AL1_18100 | Histidinol phosphatase and related hydrolases of the PHP family. (396 aa) |
| | AL1_18240 | Multimeric flavodoxin WrbA. (204 aa) |
| | AL1_18330 | dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes. (144 aa) |
| | AL1_18430 | Nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (423 aa) |
| | AL1_18470 | Hypothetical protein. (370 aa) |
| | AL1_18480 | Transcription antiterminator. (374 aa) |
| | AL1_18590 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (301 aa) |
| | AL1_18610 | dTDP-D-glucose 4,6-dehydratase. (175 aa) |
| | AL1_18760 | Hypothetical protein. (67 aa) |
| | AL1_19210 | Ribosomal subunit interface protein. (98 aa) |
| | galK | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (375 aa) |
| | AL1_19930 | rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (246 aa) |
| | AL1_20000 | Inactive homolog of metal-dependent proteases, putative molecular chaperone. (235 aa) |
| | AL1_20100 | Riboflavin synthase, alpha subunit. (198 aa) |
| | ruvB | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (335 aa) |
| | AL1_20170 | Malic enzyme. (426 aa) |
| | AL1_20180 | 3-dehydroquinate synthetase. (233 aa) |
| | AL1_20190 | 3-dehydroquinate synthetase. (107 aa) |
| | AL1_20940 | Cysteine desulfuration protein SufE. (139 aa) |
| | AL1_20950 | Predicted metal-sulfur cluster biosynthetic enzyme. (106 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (245 aa) |
| | AL1_21410 | 4-phosphoerythronate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (331 aa) |
| | rimO | SSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (432 aa) |
| | AL1_21570 | HD domain. (207 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (444 aa) |
| | AL1_21780 | Conserved hypothetical protein TIGR01033. (229 aa) |
| | AL1_21790 | Lactoylglutathione lyase and related lyases. (126 aa) |
| | AL1_21800 | Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. (193 aa) |
| | pdxJ | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (238 aa) |
| | nadK | Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa) |
| | AL1_21880 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (237 aa) |
| | AL1_21970 | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (266 aa) |
| | AL1_22110 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (850 aa) |
| | AL1_22190 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa) |
| | clpB | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (865 aa) |
| | thrS | threonyl-tRNA synthetase /Ser-tRNA(Thr) hydrolase; Belongs to the class-II aminoacyl-tRNA synthetase family. (604 aa) |
| | AL1_22350 | rRNA methylases. (251 aa) |
| | AL1_22480 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (478 aa) |
| | AL1_22960 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (519 aa) |
| | queA-2 | S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (403 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (433 aa) |
| | groL | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (543 aa) |
| | greA | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (158 aa) |
| | AL1_23200 | Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (275 aa) |
| | AL1_23220 | Aspartate kinase; Belongs to the aspartokinase family. (418 aa) |
| | asd | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa) |
| | AL1_24020 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa) |
| | AL1_24190 | Predicted metal-binding, possibly nucleic acid-binding protein. (201 aa) |
| | AL1_24380 | Uncharacterized protein related to capsule biosynthesis enzymes. (496 aa) |
| | AL1_24780 | Acetyl-CoA hydrolase. (431 aa) |
| | AL1_24820 | Transcriptional regulators. (234 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (335 aa) |
| | AL1_25310 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (318 aa) |
| | AL1_25320 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1204 aa) |
| | clpX | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (422 aa) |
| | AL1_25370 | Transketolase; Belongs to the transketolase family. (656 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (436 aa) |
| | AL1_25540 | Phosphoesterase, MJ0936 family. (164 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (584 aa) |
| | tadA | Cytosine/adenosine deaminases; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (148 aa) |
| | AL1_25720 | Sugar kinases, ribokinase family. (318 aa) |
| | AL1_25920 | Predicted SAM-dependent methyltransferases. (311 aa) |
| | AL1_26050 | Peptidyl-dipeptidase Dcp. Metallo peptidase. MEROPS family M03A. (710 aa) |
| | AL1_26060 | Peptidyl-dipeptidase Dcp. Metallo peptidase. MEROPS family M03A. (693 aa) |
| | AL1_26390 | Conserved hypothetical protein. (131 aa) |
| | AL1_26550 | Hypothetical protein. (588 aa) |
| | AL1_26830 | L-serine ammonia-lyase. (380 aa) |
| | tdk | Thymidine kinase. (191 aa) |
| | AL1_27600 | Flavodoxin, long chain; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (154 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (253 aa) |
| | AL1_27790 | Predicted O-methyltransferase. (215 aa) |
| | argS | arginyl-tRNA synthetase. (593 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (162 aa) |
| | leuD | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa) |
| | AL1_28210 | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (458 aa) |
| | AL1_28230 | L-alanine dehydrogenase; Belongs to the AlaDH/PNT family. (368 aa) |
| | AL1_28250 | Aminoacyl-histidine dipeptidase. (483 aa) |
| | AL1_28410 | Predicted flavoproteins. (423 aa) |
| | AL1_28680 | Bacterioferritin (cytochrome b1). (208 aa) |
| | AL1_28840 | Translation factor SUA5; Belongs to the SUA5 family. (200 aa) |
| | AL1_28880 | Uncharacterized conserved protein. (91 aa) |
| | AL1_29120 | ORF6N domain. (194 aa) |
| | AL1_29130 | ORF6N domain. (187 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa) |
| | panD | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (119 aa) |
| | AL1_29680 | tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (376 aa) |
| | kdsB | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (254 aa) |
| | AL1_29880 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (269 aa) |
| | AL1_29960 | Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family. (380 aa) |
| | AL1_30160 | Mismatch repair ATPase (MutS family). (526 aa) |
| | AL1_30290 | Hypothetical protein. (557 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (417 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | purN | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (186 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (341 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (238 aa) |
| | AL1_30780 | Phosphoribosylformylglycinamidine synthase. (1239 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, PurK protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (363 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (155 aa) |
| | AL1_30850 | Glutaredoxin. (86 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | AL1_30920 | Transcriptional regulators of sugar metabolism. (257 aa) |
| | AL1_30960 | Predicted sugar phosphatases of the HAD superfamily. (289 aa) |
| | AL1_31600 | HipA N-terminal domain. (106 aa) |
| | AL1_31610 | HipA-like C-terminal domain./HipA-like N-terminal domain. (336 aa) |
| | AL1_31860 | Transcriptional regulator, PadR family. (111 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (326 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. In the N-terminal section; belongs to the histidinol- phosphatase family. (375 aa) |
| | AL1_31900 | Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family. (333 aa) |
| | nusG | Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (186 aa) |
| | AL1_00590 | 4-alpha-glucanotransferase. (867 aa) |
| | nusA | Transcription termination factor NusA; Participates in both transcription termination and antitermination. (409 aa) |
