(11 nodes) Mismatch repair network (Alistipes shahii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	AL1_01660	Single stranded DNA-binding protein (ssb). (140 aa)
	ligA	DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (674 aa)
	AL1_05140	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
	AL1_05150	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases. (255 aa)
	AL1_05260	DNA polymerase III, alpha subunit. (1269 aa)
	AL1_09780	Single-stranded DNA-binding protein. (126 aa)
	AL1_15270	Hypothetical protein. (381 aa)
	AL1_16230	Exonuclease RecJ. (569 aa)
	AL1_17650	Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.; Belongs to the XseB family. (62 aa)
	AL1_25170	DNA polymerase III, delta subunit. (356 aa)
	mutL	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (664 aa)

Your Current Organism:

Alistipes shahii

NCBI taxonomy Id: 717959
Other names: A. shahii WAL 8301, Alistipes shahii WAL 8301, Alistipes shahii str. WAL 8301, Alistipes shahii strain WAL 8301, Alistipes sp. WAL 8301

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AL1_01660	AL1_05260	AL1_01660	AL1_05260	Single stranded DNA-binding protein (ssb).	DNA polymerase III, alpha subunit.	0.801
AL1_01660	AL1_09780	AL1_01660	AL1_09780	Single stranded DNA-binding protein (ssb).	Single-stranded DNA-binding protein.	0.900
AL1_01660	AL1_15270	AL1_01660	AL1_15270	Single stranded DNA-binding protein (ssb).	Hypothetical protein.	0.798
AL1_01660	AL1_16230	AL1_01660	AL1_16230	Single stranded DNA-binding protein (ssb).	Exonuclease RecJ.	0.400
AL1_05140	AL1_05150	AL1_05140	AL1_05150	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.	0.995
AL1_05140	AL1_05260	AL1_05140	AL1_05260	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, alpha subunit.	0.991
AL1_05140	AL1_15270	AL1_05140	AL1_15270	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Hypothetical protein.	0.994
AL1_05140	AL1_16230	AL1_05140	AL1_16230	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Exonuclease RecJ.	0.527
AL1_05140	AL1_25170	AL1_05140	AL1_25170	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, delta subunit.	0.993
AL1_05140	mutL	AL1_05140	AL1_26340	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.848
AL1_05150	AL1_05140	AL1_05150	AL1_05140	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.995
AL1_05150	AL1_05260	AL1_05150	AL1_05260	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.	DNA polymerase III, alpha subunit.	0.981
AL1_05150	AL1_15270	AL1_05150	AL1_15270	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.	Hypothetical protein.	0.982
AL1_05150	AL1_25170	AL1_05150	AL1_25170	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.	DNA polymerase III, delta subunit.	0.962
AL1_05260	AL1_01660	AL1_05260	AL1_01660	DNA polymerase III, alpha subunit.	Single stranded DNA-binding protein (ssb).	0.801
AL1_05260	AL1_05140	AL1_05260	AL1_05140	DNA polymerase III, alpha subunit.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.991
AL1_05260	AL1_05150	AL1_05260	AL1_05150	DNA polymerase III, alpha subunit.	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.	0.981
AL1_05260	AL1_09780	AL1_05260	AL1_09780	DNA polymerase III, alpha subunit.	Single-stranded DNA-binding protein.	0.801
AL1_05260	AL1_15270	AL1_05260	AL1_15270	DNA polymerase III, alpha subunit.	Hypothetical protein.	0.992
AL1_05260	AL1_25170	AL1_05260	AL1_25170	DNA polymerase III, alpha subunit.	DNA polymerase III, delta subunit.	0.991

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