STRINGSTRING
EC1_17770 EC1_17770 EC1_08800 EC1_08800 pstB pstB EC1_00150 EC1_00150 EC1_00320 EC1_00320 EC1_00340 EC1_00340 ftsH ftsH fhs fhs EC1_00750 EC1_00750 EC1_00760 EC1_00760 EC1_01200 EC1_01200 EC1_01810 EC1_01810 EC1_02100 EC1_02100 EC1_02510 EC1_02510 EC1_02700 EC1_02700 EC1_02710 EC1_02710 EC1_02880 EC1_02880 atpD atpD atpA atpA EC1_03070 EC1_03070 EC1_03330 EC1_03330 recA recA EC1_03700 EC1_03700 purA purA ffh ffh EC1_04040 EC1_04040 secA secA EC1_04210 EC1_04210 EC1_04220 EC1_04220 EC1_04460 EC1_04460 EC1_04660 EC1_04660 EC1_04850 EC1_04850 EC1_05130 EC1_05130 EC1_05790 EC1_05790 EC1_05910 EC1_05910 EC1_05920 EC1_05920 EC1_05930 EC1_05930 EC1_06010 EC1_06010 EC1_06050 EC1_06050 EC1_06210 EC1_06210 EC1_06300 EC1_06300 EC1_06430 EC1_06430 EC1_06440 EC1_06440 EC1_06560 EC1_06560 EC1_06680 EC1_06680 EC1_06790 EC1_06790 ecfA ecfA ecfA-2 ecfA-2 adk adk fusA fusA EC1_07440 EC1_07440 EC1_07460 EC1_07460 EC1_07470 EC1_07470 EC1_07690 EC1_07690 EC1_07800 EC1_07800 EC1_08180 EC1_08180 EC1_08190 EC1_08190 EC1_08300 EC1_08300 EC1_08310 EC1_08310 hprK hprK EC1_08770 EC1_08770 tmk tmk EC1_09510 EC1_09510 EC1_09590 EC1_09590 EC1_09600 EC1_09600 EC1_09620 EC1_09620 EC1_09670 EC1_09670 EC1_10110 EC1_10110 EC1_10120 EC1_10120 EC1_10130 EC1_10130 EC1_10240 EC1_10240 EC1_10400 EC1_10400 EC1_11060 EC1_11060 engB engB obg obg EC1_11610 EC1_11610 EC1_11620 EC1_11620 EC1_11710 EC1_11710 EC1_12830 EC1_12830 EC1_13040 EC1_13040 EC1_09060 EC1_09060 era era EC1_13540 EC1_13540 EC1_13550 EC1_13550 EC1_13730 EC1_13730 EC1_13910 EC1_13910 ftsY ftsY EC1_14600 EC1_14600 EC1_14870 EC1_14870 EC1_15050 EC1_15050 EC1_15090 EC1_15090 EC1_15200 EC1_15200 recD2 recD2 EC1_15640 EC1_15640 EC1_15810 EC1_15810 EC1_15930 EC1_15930 EC1_15990 EC1_15990 EC1_16030 EC1_16030 EC1_16330 EC1_16330 EC1_16340 EC1_16340 EC1_17160 EC1_17160 EC1_17300 EC1_17300 EC1_17310 EC1_17310 EC1_17760 EC1_17760 EC1_18160 EC1_18160 EC1_18230 EC1_18230 ftsE ftsE uvrB uvrB EC1_19010 EC1_19010 EC1_19180 EC1_19180 EC1_19390 EC1_19390 EC1_19990 EC1_19990 EC1_20500 EC1_20500 EC1_20520 EC1_20520
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EC1_17770Hypothetical protein. (68 aa)
EC1_08800Tfp pilus assembly protein, pilus retraction ATPase PilT. (196 aa)
pstBPhosphate ABC transporter ATP-binding protein, PhoT family (TC 3.A.1.7.1); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (251 aa)
EC1_00150Small GTP-binding protein domain. (382 aa)
EC1_00320DNA replication protein. (298 aa)
EC1_00340Dephospho-CoA kinase; Belongs to the CoaE family. (124 aa)
ftsHMembrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (655 aa)
fhsFormate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
EC1_00750Recombination protein MgsA. (445 aa)
EC1_00760Conserved hypothetical nucleotide-binding protein. (150 aa)
EC1_01200ABC-type multidrug transport system, ATPase component. (234 aa)
EC1_01810ABC-type multidrug transport system, ATPase and permease components. (578 aa)
EC1_02100Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (329 aa)
EC1_02510Small GTP-binding protein domain; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. (413 aa)
EC1_02700Hypothetical protein. (79 aa)
EC1_02710CobQ/CobB/MinD/ParA nucleotide binding domain. (141 aa)
EC1_02880DNA replication protein. (249 aa)
atpDATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (467 aa)
atpAATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (511 aa)
EC1_03070Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (448 aa)
EC1_03330Superfamily I DNA and RNA helicases. (564 aa)
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (334 aa)
EC1_03700Predicted nucleotide kinase. (162 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (165 aa)
ffhSignal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (471 aa)
EC1_04040Preprotein translocase subunit SecA (ATPase, RNA helicase). (147 aa)
secAProtein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (658 aa)
EC1_04210Uridine kinase. (103 aa)
EC1_04220ATPases involved in chromosome partitioning. (261 aa)
EC1_04460Type IV secretory pathway, VirD4 components. (267 aa)
EC1_04660Small GTP-binding protein domain. (639 aa)
EC1_04850ABC-type antimicrobial peptide transport system, ATPase component. (221 aa)
EC1_05130AAA domain (dynein-related subfamily). (113 aa)
EC1_05790ABC-type antimicrobial peptide transport system, ATPase component. (233 aa)
EC1_05910ABC-type multidrug transport system, ATPase and permease components. (578 aa)
EC1_05920ABC-type multidrug transport system, ATPase and permease components. (581 aa)
EC1_05930ATPase components of various ABC-type transport systems, contain duplicated ATPase. (490 aa)
EC1_06010Domain of unknown function DUF87. (784 aa)
EC1_06050Type IV secretory pathway, VirD4 components. (600 aa)
EC1_06210DNA methylase. (2848 aa)
EC1_06300ATPases involved in chromosome partitioning. (272 aa)
EC1_06430ABC-type multidrug transport system, ATPase and permease components. (574 aa)
EC1_06440ABC-type multidrug transport system, ATPase and permease components. (585 aa)
EC1_06560Type IV secretory pathway, VirD4 components. (607 aa)
EC1_06680DNA methylase. (3253 aa)
EC1_06790ATPases involved in chromosome partitioning. (282 aa)
ecfAABC-type cobalt transport system, ATPase component; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (286 aa)
ecfA-2ABC-type cobalt transport system, ATPase component; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (275 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa)
fusATranslation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (699 aa)
EC1_07440ABC-type antimicrobial peptide transport system, ATPase component. (226 aa)
EC1_07460Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family (TC 3.A.1.4.-). (236 aa)
EC1_07470Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family (TC 3.A.1.4.-). (259 aa)
EC1_07690ABC-type multidrug transport system, ATPase component. (240 aa)
EC1_07800Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein). (385 aa)
EC1_08180ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. (492 aa)
EC1_08190ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); ATP-dependent DNA helicase. (558 aa)
EC1_08300ABC-type multidrug transport system, ATPase and permease components. (292 aa)
EC1_08310ABC-type multidrug transport system, ATPase and permease components. (583 aa)
hprKHpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] (313 aa)
EC1_08770Hypothetical protein. (200 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa)
EC1_09510Rad3-related DNA helicases. (658 aa)
EC1_09590ABC-type multidrug transport system, ATPase and permease components. (582 aa)
EC1_09600ABC-type multidrug transport system, ATPase and permease components. (594 aa)
EC1_09620ABC-type cobalt transport system, ATPase component. (195 aa)
EC1_09670Hypothetical protein. (778 aa)
EC1_10110ABC-type multidrug transport system, ATPase and permease components. (582 aa)
EC1_10120ABC-type multidrug transport system, ATPase and permease components. (602 aa)
EC1_10130ATPase components of various ABC-type transport systems, contain duplicated ATPase. (493 aa)
EC1_10240DNA methylase. (2929 aa)
EC1_10400Type IV secretory pathway, VirD4 components. (609 aa)
EC1_11060FeS assembly ATPase SufC. (271 aa)
engBRibosome biogenesis GTP-binding protein YsxC/EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (189 aa)
obgObg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (427 aa)
EC1_11610Hypothetical protein. (50 aa)
EC1_11620ABC-type antimicrobial peptide transport system, ATPase component. (143 aa)
EC1_11710RecG-like helicase. (497 aa)
EC1_12830ATPases involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (278 aa)
EC1_13040DNA polymerase III, delta subunit. (268 aa)
EC1_09060ABC-type antimicrobial peptide transport system, ATPase component. (874 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (300 aa)
EC1_13540Hypothetical protein. (59 aa)
EC1_13550Hypothetical protein. (117 aa)
EC1_13730Hypothetical protein. (61 aa)
EC1_13910ATPase involved in DNA replication initiation; Belongs to the DnaA family. (123 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (321 aa)
EC1_14600SMC proteins Flexible Hinge Domain./RecF/RecN/SMC N terminal domain. (526 aa)
EC1_14870ABC-type polar amino acid transport system, ATPase component. (243 aa)
EC1_15050ABC-type multidrug transport system, ATPase and permease components. (1161 aa)
EC1_15090Predicted ATPase (AAA+ superfamily). (387 aa)
EC1_15200ATPase components of ABC transporters with duplicated ATPase domains. (572 aa)
recD2Helicase, putative, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (715 aa)
EC1_15640DNA translocase FtsK; Belongs to the FtsK/SpoIIIE/SftA family. (738 aa)
EC1_15810Hypothetical protein. (182 aa)
EC1_15930ATPase components of ABC transporters with duplicated ATPase domains. (583 aa)
EC1_15990ABC-type uncharacterized transport system, ATPase component. (250 aa)
EC1_16030ABC-type uncharacterized transport system, ATPase component. (264 aa)
EC1_16330Hypothetical protein. (153 aa)
EC1_16340Hypothetical protein. (32 aa)
EC1_17160Hydrogenase accessory protein HypB. (221 aa)
EC1_17300ABC-type antimicrobial peptide transport system, ATPase component. (134 aa)
EC1_17310ABC-type antimicrobial peptide transport system, ATPase component. (115 aa)
EC1_17760ABC-type polar amino acid transport system, ATPase component. (164 aa)
EC1_18160ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily. (347 aa)
EC1_18230Cytidylate kinase. (305 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (655 aa)
EC1_19010Predicted GTPase. (446 aa)
EC1_19180Hypothetical protein. (109 aa)
EC1_19390ATPase family associated with various cellular activities (AAA). (490 aa)
EC1_19990Superfamily II DNA/RNA helicases, SNF2 family. (473 aa)
EC1_20500Predicted HKD family nuclease. (275 aa)
EC1_20520Predicted ATPase (AAA+ superfamily). (410 aa)
Your Current Organism:
Faecalitalea cylindroides
NCBI taxonomy Id: 717960
Other names: Eubacterium cylindroides T2-87, F. cylindroides T2-87, Faecalitalea cylindroides T2-87
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