(19 nodes) Renal cortex network (Bos mutus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UMOD	Uromodulin. (643 aa)
	SLC28A2	Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (659 aa)
	SLC17A1	Sodium-dependent phosphate transport protein 1. (468 aa)
	ACTBL2	Beta-actin-like protein 2. (376 aa)
	SLC22A20P	Solute carrier family 22 member 20. (555 aa)
	LRP2	Low density lipoprotein-related protein 2. (4641 aa)
	ANPEP	Aminopeptidase. (980 aa)
	SLC28A1	Pyrimidine nucleoside transport protein. (650 aa)
	CUBN	Cubilin. (3613 aa)
	ACTL8	Actin-like protein 8; Belongs to the actin family. (365 aa)
	FBP1	Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
	DPEP1	Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (406 aa)
	RENBP	N-acylglucosamine 2-epimerase. (411 aa)
	ATP6V1A	V-type proton ATPase catalytic subunit A. (618 aa)
	SLC28A3	Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (697 aa)
	ACTB	Actin, cytoplasmic 1. (375 aa)
	LOC102279207	MFS domain-containing protein. (538 aa)
	SLC22A6	Solute carrier family 22 member 6. (550 aa)
	ACTG1	Actin, cytoplasmic 2. (375 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTG1	ENSBMUP00000028239	ENSBMUP00000035569	Actin, cytoplasmic 1.	Actin, cytoplasmic 2.	0.943
ACTG1	ACTB	ENSBMUP00000035569	ENSBMUP00000028239	Actin, cytoplasmic 2.	Actin, cytoplasmic 1.	0.943
CUBN	LRP2	ENSBMUP00000011142	ENSBMUP00000004357	Cubilin.	Low density lipoprotein-related protein 2.	0.800
CUBN	SLC17A1	ENSBMUP00000011142	ENSBMUP00000001333	Cubilin.	Sodium-dependent phosphate transport protein 1.	0.743
CUBN	UMOD	ENSBMUP00000011142	ENSBMUP00000004956	Cubilin.	Uromodulin.	0.468
LRP2	CUBN	ENSBMUP00000004357	ENSBMUP00000011142	Low density lipoprotein-related protein 2.	Cubilin.	0.800
LRP2	UMOD	ENSBMUP00000004357	ENSBMUP00000004956	Low density lipoprotein-related protein 2.	Uromodulin.	0.546
SLC17A1	CUBN	ENSBMUP00000001333	ENSBMUP00000011142	Sodium-dependent phosphate transport protein 1.	Cubilin.	0.743
UMOD	CUBN	ENSBMUP00000004956	ENSBMUP00000011142	Uromodulin.	Cubilin.	0.468
UMOD	LRP2	ENSBMUP00000004956	ENSBMUP00000004357	Uromodulin.	Low density lipoprotein-related protein 2.	0.546