(10 nodes) Abdominal aorta network (Bos mutus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACTBL2	Beta-actin-like protein 2. (376 aa)
	SERPINE1	Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (456 aa)
	ACTG1	Actin, cytoplasmic 2. (375 aa)
	ACTL8	Actin-like protein 8; Belongs to the actin family. (365 aa)
	ELN	Elastin. (718 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	ACTA2	Actin, alpha 2, smooth muscle, aorta. (377 aa)
	ACTB	Actin, cytoplasmic 1. (375 aa)
	FBN1	Fibrillin-1. (2773 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA2	FBN1	ENSBMUP00000022111	ENSBMUP00000030079	Actin, alpha 2, smooth muscle, aorta.	Fibrillin-1.	0.419
ACTB	ACTG1	ENSBMUP00000028239	ENSBMUP00000035569	Actin, cytoplasmic 1.	Actin, cytoplasmic 2.	0.943
ACTB	CAV1	ENSBMUP00000028239	ENSBMUP00000018309	Actin, cytoplasmic 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.703
ACTB	ELN	ENSBMUP00000028239	ENSBMUP00000014060	Actin, cytoplasmic 1.	Elastin.	0.438
ACTB	SERPINE1	ENSBMUP00000028239	ENSBMUP00000007808	Actin, cytoplasmic 1.	Plasminogen activator inhibitor 1; Belongs to the serpin family.	0.537
ACTBL2	CAV1	ENSBMUP00000001808	ENSBMUP00000018309	Beta-actin-like protein 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.438
ACTG1	ACTB	ENSBMUP00000035569	ENSBMUP00000028239	Actin, cytoplasmic 2.	Actin, cytoplasmic 1.	0.943
ACTG1	CAV1	ENSBMUP00000035569	ENSBMUP00000018309	Actin, cytoplasmic 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.494
ACTL8	CAV1	ENSBMUP00000013416	ENSBMUP00000018309	Actin-like protein 8; Belongs to the actin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.438
AGT	SERPINE1	ENSBMUP00000009074	ENSBMUP00000007808	Angiotensinogen; Belongs to the serpin family.	Plasminogen activator inhibitor 1; Belongs to the serpin family.	0.477
CAV1	ACTB	ENSBMUP00000018309	ENSBMUP00000028239	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Actin, cytoplasmic 1.	0.703
CAV1	ACTBL2	ENSBMUP00000018309	ENSBMUP00000001808	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Beta-actin-like protein 2.	0.438
CAV1	ACTG1	ENSBMUP00000018309	ENSBMUP00000035569	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Actin, cytoplasmic 2.	0.494
CAV1	ACTL8	ENSBMUP00000018309	ENSBMUP00000013416	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Actin-like protein 8; Belongs to the actin family.	0.438
ELN	ACTB	ENSBMUP00000014060	ENSBMUP00000028239	Elastin.	Actin, cytoplasmic 1.	0.438
ELN	FBN1	ENSBMUP00000014060	ENSBMUP00000030079	Elastin.	Fibrillin-1.	0.867
FBN1	ACTA2	ENSBMUP00000030079	ENSBMUP00000022111	Fibrillin-1.	Actin, alpha 2, smooth muscle, aorta.	0.419
FBN1	ELN	ENSBMUP00000030079	ENSBMUP00000014060	Fibrillin-1.	Elastin.	0.867
SERPINE1	ACTB	ENSBMUP00000007808	ENSBMUP00000028239	Plasminogen activator inhibitor 1; Belongs to the serpin family.	Actin, cytoplasmic 1.	0.537
SERPINE1	AGT	ENSBMUP00000007808	ENSBMUP00000009074	Plasminogen activator inhibitor 1; Belongs to the serpin family.	Angiotensinogen; Belongs to the serpin family.	0.477