STRINGSTRING
EXOSC9 EXOSC9 PDCD11 PDCD11 EXOSC10 EXOSC10 NOB1 NOB1 HEATR1 HEATR1 NEXN NEXN NIP7 NIP7 UTP4 UTP4 IMP3 IMP3 GCC1 GCC1 TRMT10B TRMT10B EXOSC3 EXOSC3 RBM28 RBM28 NOM1 NOM1 DDX10 DDX10 RBM34 RBM34 NIFK NIFK FBLL1 FBLL1 LYAR LYAR BRIX1 BRIX1 PINX1 PINX1 PAK1IP1 PAK1IP1 MCC MCC THUMPD1 THUMPD1 NMD3 NMD3 GTPBP4 GTPBP4 DDX31 DDX31 NOP53 NOP53 KCTD19 KCTD19 PWP1 PWP1 RBM19 RBM19 KRI1 KRI1 EIF6 EIF6 UTP11 UTP11 GNL3 GNL3 RCL1 RCL1 AATF AATF MRTO4 MRTO4 GNL2 GNL2 NCOA6 NCOA6 MAK16 MAK16 CEBPZ CEBPZ FTSJ1 FTSJ1 DDX52 DDX52 DIS3L DIS3L EXOSC2 EXOSC2 LOC102275867 LOC102275867 EXOSC7 EXOSC7 FTSJ3 FTSJ3 SKIV2L SKIV2L NVL NVL UTP3 UTP3 IMP4 IMP4 UTP25 UTP25 LTV1 LTV1 WDR61 WDR61 FCF1 FCF1 NSUN5 NSUN5 RETREG1 RETREG1 ZNF622 ZNF622 ENSBMUP00000010461 ENSBMUP00000010461 NOP9 NOP9 BUD23 BUD23 RBM7 RBM7 RRP9 RRP9 NOP2 NOP2 NAT10 NAT10 RRP15 RRP15 LOC102280190 LOC102280190 WDR46 WDR46 PES1 PES1 RSL24D1 RSL24D1 NSUN6 NSUN6 UTP20 UTP20 NOL11 NOL11 DDX47 DDX47 TTC4 TTC4 NOL12 NOL12 EMG1 EMG1 UTP6 UTP6 TRMT44 TRMT44 ENSBMUP00000014714 ENSBMUP00000014714 DIMT1 DIMT1 DDX27 DDX27 WDR4 WDR4 LSG1 LSG1 WDR43 WDR43 TRMT61B TRMT61B WDR3 WDR3 GNL3L GNL3L RRP1B RRP1B RRP36 RRP36 RRP1 RRP1 NLE1 NLE1 PWP2 PWP2 DDX55 DDX55 UTP14A UTP14A WDR6 WDR6 PUM3 PUM3 ENSBMUP00000018356 ENSBMUP00000018356 BYSL BYSL EXOSC8 EXOSC8 GLMN GLMN RRS1 RRS1 DDX18 DDX18 DDX49 DDX49 TRMT1 TRMT1 DNTTIP2 DNTTIP2 RRP7A RRP7A RSL1D1 RSL1D1 NSUN3 NSUN3 FBL FBL WDR55 WDR55 TRMT6 TRMT6 ZNF593 ZNF593 ENSBMUP00000021619 ENSBMUP00000021619 UTP23 UTP23 DDX24 DDX24 SNU13 SNU13 GRWD1 GRWD1 SDAD1 SDAD1 PA2G4 PA2G4 RPF2 RPF2 ENSBMUP00000022908 ENSBMUP00000022908 ZCCHC8 ZCCHC8 ESF1 ESF1 NOL6 NOL6 PMEL PMEL BMS1 BMS1 TBL3 TBL3 NOP58 NOP58 NSA2 NSA2 WDR12 WDR12 DHX37 DHX37 TTC27 TTC27 NOL10 NOL10 UTP18 UTP18 RRP12 RRP12 M91_05028 M91_05028 EXOSC1 EXOSC1 DDX54 DDX54 EBNA1BP2 EBNA1BP2 NOP56 NOP56 RIOK2 RIOK2 NOC3L NOC3L C1D C1D PNO1 PNO1 TRMT61A TRMT61A P2RY11 P2RY11 LOC102276062 LOC102276062 TTC37 TTC37 TSR1 TSR1 RIOK3 RIOK3 NOC4L NOC4L ENSBMUP00000029771 ENSBMUP00000029771 SURF6 SURF6 PUS1 PUS1 MPHOSPH10 MPHOSPH10 WDR75 WDR75 RTCA RTCA UTP15 UTP15 MTREX MTREX EXOSC5 EXOSC5 WDR74 WDR74 DIS3 DIS3 EXOSC4 EXOSC4 HGH1 HGH1 RPF1 RPF1 BOP1 BOP1 KRR1 KRR1 ABT1 ABT1 NSUN2 NSUN2 LOC102264383 LOC102264383 THADA THADA WDR36 WDR36 NOP14 NOP14 TRMT5 TRMT5 METTL1 METTL1 NOC2L NOC2L ENSBMUP00000034706 ENSBMUP00000034706 DUS3L DUS3L DCAF13 DCAF13 RETREG2 RETREG2 MPHOSPH6 MPHOSPH6 DDX56 DDX56 M91_16460 M91_16460 DUS1L DUS1L NGDN NGDN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EXOSC9Exosome complex exonuclease RRP45. (440 aa)
PDCD11Protein RRP5-like protein. (1874 aa)
EXOSC10Exosome complex exonuclease RRP6. (880 aa)
NOB1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (459 aa)
HEATR1U3 small nucleolar RNA-associated protein 10. (2021 aa)
NEXNNexilin. (675 aa)
NIP760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (217 aa)
UTP4Cirhin. (686 aa)
IMP3U3 small nucleolar ribonucleoprotein IMP3. (184 aa)
GCC1GRIP and coiled-coil domain-containing protein 1. (775 aa)
TRMT10BRNA (Guanine-9-)-methyltransferase domain-containing protein 3. (316 aa)
EXOSC3Exosome complex exonuclease RRP40. (275 aa)
RBM28RNA-binding protein 28. (751 aa)
NOM1Nucleolar MIF4G domain-containing protein 1. (721 aa)
DDX10RNA helicase. (876 aa)
RBM34RNA-binding protein 34. (428 aa)
NIFKMKI67 FHA domain-interacting nucleolar phosphoprotein. (296 aa)
FBLL1rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1. (333 aa)
LYARCell growth-regulating nucleolar protein. (382 aa)
BRIX1Ribosome biogenesis protein BRX1-like protein. (353 aa)
PINX1PIN2/TERF1 interacting, telomerase inhibitor 1. (309 aa)
PAK1IP1P21-activated protein kinase-interacting protein 1. (389 aa)
MCCColorectal mutant cancer protein. (1021 aa)
THUMPD1THUMP domain-containing protein 1. (356 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (503 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
DDX31RNA helicase. (778 aa)
NOP53Glioma tumor suppressor candidate region 2 protein. (483 aa)
KCTD19Potassium channel tetramerization domain containing 19. (917 aa)
PWP1Periodic tryptophan protein 1-like protein. (500 aa)
RBM19Putative RNA-binding protein 19. (946 aa)
KRI1Protein KRI1-like protein. (711 aa)
EIF6Eukaryotic translation initiation factor 6. (245 aa)
UTP11U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (253 aa)
GNL3Guanine nucleotide-binding protein-like 3. (547 aa)
RCL1RNA 3'-terminal phosphate cyclase-like protein. (373 aa)
AATFProtein AATF. (355 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (732 aa)
NCOA6Nuclear receptor coactivator 6. (2048 aa)
MAK16Protein MAK16 homolog; Belongs to the MAK16 family. (298 aa)
CEBPZCCAAT/enhancer-binding protein zeta. (1060 aa)
FTSJ1Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (329 aa)
DDX52Putative ATP-dependent RNA helicase DDX52. (596 aa)
DIS3LDIS3-like exonuclease 1; Belongs to the RNR ribonuclease family. (995 aa)
EXOSC2Exosome complex exonuclease RRP4. (293 aa)
LOC102275867Uncharacterized protein. (801 aa)
EXOSC7Exosome complex exonuclease RRP42. (291 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (833 aa)
SKIV2LHelicase SKI2W. (1246 aa)
NVLNuclear valosin-containing protein-like protein. (855 aa)
UTP3Something about silencing protein 10. (474 aa)
IMP4U3 small nucleolar ribonucleoprotein IMP4. (291 aa)
UTP25Digestive organ expansion factor-like protein. (753 aa)
LTV1Protein LTV1-like protein. (475 aa)
WDR61WD repeat-containing protein 61. (327 aa)
FCF1rRNA-processing protein FCF1-like protein. (198 aa)
NSUN5Putative methyltransferase NSUN5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (462 aa)
RETREG1Protein FAM134B. (360 aa)
ZNF622Zinc finger protein 622. (506 aa)
ENSBMUP00000010461annotation not available (80 aa)
NOP9Uncharacterized protein. (637 aa)
BUD23Putative methyltransferase WBSCR22. (281 aa)
RBM7RNA-binding protein 7. (262 aa)
RRP9U3 small nucleolar RNA-interacting protein 2. (475 aa)
NOP2Putative ribosomal RNA methyltransferase NOP2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (823 aa)
NAT10N-acetyltransferase 10. (1026 aa)
RRP15RRP15-like protein. (307 aa)
LOC102280190Uncharacterized protein. (185 aa)
WDR46WD repeat-containing protein 46. (677 aa)
PES1Pescadillo-like protein. (536 aa)
RSL24D1Putative ribosome biogenesis protein RLP24. (198 aa)
NSUN6Putative methyltransferase NSUN6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (470 aa)
UTP20U3 small nucleolar RNA-associated protein 20. (2778 aa)
NOL11Nucleolar protein 11. (718 aa)
DDX47Putative ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (426 aa)
TTC4Tetratricopeptide repeat protein 4. (419 aa)
NOL12Nucleolar protein 12. (214 aa)
EMG1Putative ribosome biogenesis protein NEP1. (244 aa)
UTP6U3 small nucleolar RNA-associated protein 6-like protein. (598 aa)
TRMT44Putative tRNA (Uracil-O(2)-)-methyltransferase. (399 aa)
ENSBMUP00000014714annotation not available (154 aa)
DIMT1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (420 aa)
DDX27Putative ATP-dependent RNA helicase DDX27; Belongs to the DEAD box helicase family. (734 aa)
WDR4tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (453 aa)
LSG1Large subunit GTPase 1-like protein. (649 aa)
WDR43WD repeat-containing protein 43. (681 aa)
TRMT61BPutative tRNA (Adenine-N(1)-)-methyltransferase catalytic subunit TRMT61B. (496 aa)
WDR3WD repeat-containing protein 3. (943 aa)
GNL3LGuanine nucleotide-binding protein-like 3-like protein. (585 aa)
RRP1BRibosomal RNA processing protein 1-like protein B. (725 aa)
RRP36Ribosomal RNA-processing protein 36. (246 aa)
RRP1Ribosomal RNA processing protein 1-like protein A. (446 aa)
NLE1Notchless protein-like protein 1. (487 aa)
PWP2Periodic tryptophan protein 2-like protein. (921 aa)
DDX55RNA helicase. (601 aa)
UTP14AU3 small nucleolar RNA-associated protein 14-like protein A. (769 aa)
WDR6WD repeat domain 6. (1181 aa)
PUM3Pumilio domain-containing protein KIAA0020. (630 aa)
ENSBMUP00000018356annotation not available (111 aa)
BYSLEssential nuclear protein 1. (274 aa)
EXOSC8Exosome complex exonuclease RRP43. (276 aa)
GLMNGlomulin. (592 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
DDX18RNA helicase. (760 aa)
DDX49Putative ATP-dependent RNA helicase DDX49; Belongs to the DEAD box helicase family. (483 aa)
TRMT1N(2),N(2)-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (676 aa)
DNTTIP2Deoxynucleotidyltransferase terminal-interacting protein 2. (767 aa)
RRP7ARibosomal RNA-processing protein 7-like protein A. (280 aa)
RSL1D1Ribosomal L1 domain-containing protein 1. (479 aa)
NSUN3Putative methyltransferase NSUN3; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (340 aa)
FBLrRNA 2'-O-methyltransferase fibrillarin. (322 aa)
WDR55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (382 aa)
TRMT6tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. (497 aa)
ZNF593Bud site selection protein 20. (134 aa)
ENSBMUP00000021619annotation not available (67 aa)
UTP23rRNA-processing protein UTP23-like protein. (248 aa)
DDX24ATP-dependent RNA helicase DDX24. (813 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
GRWD1Glutamate-rich WD repeat-containing protein 1. (446 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (688 aa)
PA2G4Proliferation-associated protein 2G4. (394 aa)
RPF2Ribosome production factor 2-like protein. (306 aa)
ENSBMUP00000022908annotation not available (121 aa)
ZCCHC8Zinc finger CCHC domain-containing protein 8. (707 aa)
ESF1ESF1-like protein. (858 aa)
NOL6Nucleolar protein 6. (1146 aa)
PMELMelanocyte protein Pmel 17. (698 aa)
BMS1Ribosome biogenesis protein BMS1-like protein. (872 aa)
TBL3Transducin beta-like protein 3. (802 aa)
NOP58Nucleolar protein 58. (531 aa)
NSA2Ribosome biogenesis protein NSA2-like protein. (259 aa)
WDR12Ribosome biogenesis protein WDR12. (423 aa)
DHX37Putative ATP-dependent RNA helicase DHX37. (1147 aa)
TTC27Tetratricopeptide repeat protein 27. (820 aa)
NOL10Nucleolar protein 10. (688 aa)
UTP18U3 small nucleolar RNA-associated protein 18-like protein. (564 aa)
RRP12RRP12-like protein. (1297 aa)
M91_05028Uncharacterized protein. (181 aa)
EXOSC13'-5' exoribonuclease CSL4-like protein. (195 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (877 aa)
EBNA1BP2Putative rRNA-processing protein EBP2. (504 aa)
NOP56Nucleolar protein 56. (596 aa)
RIOK2Serine/threonine-protein kinase RIO2. (551 aa)
NOC3LNucleolar complex protein 3-like protein. (481 aa)
C1DNuclear nucleic acid-binding protein C1D. (141 aa)
PNO1RNA-binding protein PNO1. (252 aa)
TRMT61AtRNA (Adenine-N(1)-)-methyltransferase catalytic subunit TRMT61A. (300 aa)
P2RY11Purinergic receptor P2Y11. (374 aa)
LOC102276062Suppressor of SWI4 1-like protein; Belongs to the G-protein coupled receptor 1 family. (469 aa)
TTC37Tetratricopeptide repeat protein 37. (1563 aa)
TSR1Pre-rRNA-processing protein TSR1-like protein. (803 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
NOC4LNucleolar complex protein 4-like protein. (516 aa)
ENSBMUP00000029771annotation not available (100 aa)
SURF6SURF6 domain-containing protein. (353 aa)
PUS1tRNA pseudouridine synthase A, mitochondrial. (433 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10-like. (677 aa)
WDR75WD repeat-containing protein 75. (834 aa)
RTCARNA 3'-terminal phosphate cyclase. (379 aa)
UTP15U3 small nucleolar RNA-associated protein 15-like protein. (519 aa)
MTREXSuperkiller viralicidic activity 2-like 2. (1023 aa)
EXOSC5Exosome complex component RRP46. (235 aa)
WDR74WD repeat-containing protein 74. (421 aa)
DIS3Exosome complex exonuclease RRP44; Belongs to the RNR ribonuclease family. (958 aa)
EXOSC4Exosome complex exonuclease RRP41. (245 aa)
HGH1Brain protein 16. (385 aa)
RPF1Ribosome production factor 1. (391 aa)
BOP1Ribosome biogenesis protein BOP1. (708 aa)
KRR1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (382 aa)
ABT1Activator of basal transcription 1. (275 aa)
NSUN2tRNA (Cytosine-5-)-methyltransferase NSUN2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (840 aa)
LOC102264383Essential nuclear protein 1. (423 aa)
THADATHADA, armadillo repeat containing. (1951 aa)
WDR36WD repeat-containing protein 36. (895 aa)
NOP14Nucleolar protein 14. (843 aa)
TRMT5tRNA (Guanine-N(1)-)-methyltransferase. (497 aa)
METTL1tRNA (guanine(46)-N(7))-methyltransferase. (277 aa)
NOC2LNucleolar complex protein 2-like protein. (749 aa)
ENSBMUP00000034706annotation not available (56 aa)
DUS3LDihydrouridine synthase 3 like. (648 aa)
DCAF13DDB1- and CUL4-associated factor 13. (445 aa)
RETREG2Protein FAM134A. (507 aa)
MPHOSPH6M-phase phosphoprotein 6. (160 aa)
DDX56Putative ATP-dependent RNA helicase DDX56. (546 aa)
M91_16460PINc domain-containing protein. (165 aa)
DUS1LtRNA-dihydrouridine synthase 1-like protein. (475 aa)
NGDNNeuroguidin. (339 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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