(38 nodes) Proton-transporting V-type ATPase complex network (Bos mutus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	ATP6V1B1	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
	ATP6V1B2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
	ATP6V0B	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
	ATP6V0D1	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	RNASEK	Ribonuclease kappa. (98 aa)
	ENSBMUP00000006145	annotation not available (102 aa)
	ATP6V0A4-2	V-type H+-transporting ATPase subunit a. (135 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (819 aa)
	ATP6V1E2	V-type proton ATPase subunit E 2. (226 aa)
	ATP6AP1L	V-type proton ATPase subunit S1-like protein. (278 aa)
	ENSBMUP00000011052	annotation not available (81 aa)
	ATP6V1E1	V-type proton ATPase subunit E 1. (226 aa)
	LIM2	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
	ATP6V1D	V-type proton ATPase subunit D. (247 aa)
	CNST	Consortin. (721 aa)
	ATP6V0E2	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	ATP6V0D2	V-type proton ATPase subunit d 2. (351 aa)
	M91_00880	Uncharacterized protein. (74 aa)
	ATP6AP2	Renin receptor. (301 aa)
	ATP6V0A2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
	ATP6V1H	V-type H+-transporting ATPase subunit H. (483 aa)
	ATP6V1G2	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (136 aa)
	TLDC1	TLD domain-containing protein KIAA1609. (408 aa)
	ENSBMUP00000018964	annotation not available (194 aa)
	ATP6V1G1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	ATP6V1G3	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	ATP6V1A	V-type proton ATPase catalytic subunit A. (618 aa)
	ATP6V0A1	V-type H+-transporting ATPase subunit a. (838 aa)
	ATP6V0E1	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	ENSBMUP00000024193	annotation not available (220 aa)
	ATP6V1C2	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (437 aa)
	ENSBMUP00000025799	annotation not available (100 aa)
	ENSBMUP00000026546	annotation not available (93 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	ATP6V1F	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	ATP6V0A4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (792 aa)
	ATP6V1C1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
	ATP6AP1	ATPase H+ transporting accessory protein 1. (460 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6AP1	ATP6AP2	ENSBMUP00000036239	ENSBMUP00000014596	ATPase H+ transporting accessory protein 1.	Renin receptor.	0.997
ATP6AP1	ATP6V0A1	ENSBMUP00000036239	ENSBMUP00000021565	ATPase H+ transporting accessory protein 1.	V-type H+-transporting ATPase subunit a.	0.999
ATP6AP1	ATP6V0A2	ENSBMUP00000036239	ENSBMUP00000017480	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.989
ATP6AP1	ATP6V0A4	ENSBMUP00000036239	ENSBMUP00000034372	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.803
ATP6AP1	ATP6V0A4-2	ENSBMUP00000036239	ENSBMUP00000006164	ATPase H+ transporting accessory protein 1.	V-type H+-transporting ATPase subunit a.	0.979
ATP6AP1	ATP6V0B	ENSBMUP00000036239	ENSBMUP00000003951	ATPase H+ transporting accessory protein 1.	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	0.999
ATP6AP1	ATP6V0C	ENSBMUP00000036239	ENSBMUP00000029624	ATPase H+ transporting accessory protein 1.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
ATP6AP1	ATP6V0D1	ENSBMUP00000036239	ENSBMUP00000004694	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
ATP6AP1	ATP6V0D2	ENSBMUP00000036239	ENSBMUP00000014195	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit d 2.	0.994
ATP6AP1	ATP6V0E1	ENSBMUP00000036239	ENSBMUP00000023262	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.920
ATP6AP1	ATP6V0E2	ENSBMUP00000036239	ENSBMUP00000013625	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.977
ATP6AP1	ATP6V1A	ENSBMUP00000036239	ENSBMUP00000020905	ATPase H+ transporting accessory protein 1.	V-type proton ATPase catalytic subunit A.	0.999
ATP6AP1	ATP6V1B1	ENSBMUP00000036239	ENSBMUP00000001520	ATPase H+ transporting accessory protein 1.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.979
ATP6AP1	ATP6V1B2	ENSBMUP00000036239	ENSBMUP00000003073	ATPase H+ transporting accessory protein 1.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.982
ATP6AP1	ATP6V1C1	ENSBMUP00000036239	ENSBMUP00000035009	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
ATP6AP1	ATP6V1C2	ENSBMUP00000036239	ENSBMUP00000024342	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.875
ATP6AP1	ATP6V1D	ENSBMUP00000036239	ENSBMUP00000011674	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit D.	0.999
ATP6AP1	ATP6V1E1	ENSBMUP00000036239	ENSBMUP00000011268	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit E 1.	0.999
ATP6AP1	ATP6V1E2	ENSBMUP00000036239	ENSBMUP00000006387	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit E 2.	0.933
ATP6AP1	ATP6V1F	ENSBMUP00000036239	ENSBMUP00000030985	ATPase H+ transporting accessory protein 1.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.992