STRINGSTRING
M91_03257 M91_03257 ENSBMUP00000000180 ENSBMUP00000000180 M91_11341 M91_11341 UBE2Z UBE2Z M91_06400 M91_06400 ENSBMUP00000001831 ENSBMUP00000001831 NFATC2IP NFATC2IP SENP1 SENP1 UBE2B UBE2B UBE3C UBE3C ENSBMUP00000003025 ENSBMUP00000003025 M91_12934 M91_12934 UBE2Q2 UBE2Q2 RNF169 RNF169 M91_16898 M91_16898 CDC34 CDC34 ENSBMUP00000005059 ENSBMUP00000005059 ABRAXAS1 ABRAXAS1 ENSBMUP00000005800 ENSBMUP00000005800 SAE1 SAE1 ENSBMUP00000006401 ENSBMUP00000006401 ENSBMUP00000007008 ENSBMUP00000007008 ENSBMUP00000007365 ENSBMUP00000007365 UBE2N UBE2N PIAS1 PIAS1 PIAS3 PIAS3 ENSBMUP00000008758 ENSBMUP00000008758 ZMIZ2 ZMIZ2 ENSBMUP00000009019 ENSBMUP00000009019 BRCC3 BRCC3 CNFN CNFN RANBP2 RANBP2 MDC1 MDC1 ENSBMUP00000009984 ENSBMUP00000009984 ENSBMUP00000010118 ENSBMUP00000010118 UBR1 UBR1 KCTD2 KCTD2 UBE2U UBE2U SUMO2 SUMO2 LOC102272795 LOC102272795 RNF165 RNF165 LOC102272480 LOC102272480 UBE2W UBE2W SENP7 SENP7 UBE2A UBE2A UBE2G1 UBE2G1 ENSBMUP00000013730 ENSBMUP00000013730 ENSBMUP00000013748 ENSBMUP00000013748 SENP2 SENP2 UBE2O UBE2O UBE2Q1 UBE2Q1 ENSBMUP00000014459 ENSBMUP00000014459 UBE2V2 UBE2V2 ENSBMUP00000014858 ENSBMUP00000014858 TMEM189 TMEM189 UBE2V1 UBE2V1 UBA6 UBA6 RAD18 RAD18 ENSBMUP00000015985 ENSBMUP00000015985 ENSBMUP00000016033 ENSBMUP00000016033 ENSBMUP00000016303 ENSBMUP00000016303 ENSBMUP00000016464 ENSBMUP00000016464 PIAS2 PIAS2 ENSBMUP00000016987 ENSBMUP00000016987 BABAM2 BABAM2 UBR2 UBR2 ENSBMUP00000018262 ENSBMUP00000018262 ENSBMUP00000018439 ENSBMUP00000018439 ZNF451 ZNF451 RLIM RLIM LOC102271309 LOC102271309 UBE2D2 UBE2D2 MGLL MGLL ENSBMUP00000020374 ENSBMUP00000020374 UBE2D1 UBE2D1 RNF8 RNF8 UBE2K UBE2K RANGAP1 RANGAP1 CCDC197 CCDC197 ENSBMUP00000022134 ENSBMUP00000022134 UBE2R2 UBE2R2 SUMO1 SUMO1 ENSBMUP00000024181 ENSBMUP00000024181 UBC UBC ENSBMUP00000024507 ENSBMUP00000024507 UIMC1 UIMC1 PIAS4 PIAS4 RIF1 RIF1 RNF44 RNF44 ENSBMUP00000026682 ENSBMUP00000026682 UBOX5 UBOX5 TP53BP1 TP53BP1 BABAM1 BABAM1 PLAC8 PLAC8 UBE2J1 UBE2J1 RNF168 RNF168 SENP5 SENP5 ENSBMUP00000029324 ENSBMUP00000029324 ENSBMUP00000029638 ENSBMUP00000029638 PAXIP1 PAXIP1 HLTF HLTF LONRF2 LONRF2 M91_19001 M91_19001 ZNF281 ZNF281 UBA2 UBA2 UBE2I UBE2I HACE1 HACE1 M91_15717 M91_15717 UBE2H UBE2H STUB1 STUB1 ENSBMUP00000032263 ENSBMUP00000032263 LOC102269547 LOC102269547 ENSBMUP00000032580 ENSBMUP00000032580 UBE2J2 UBE2J2 C1QTNF12 C1QTNF12 RNF4 RNF4 DSPP DSPP RNF38 RNF38 ENSBMUP00000034243 ENSBMUP00000034243 UBA1 UBA1 SENP6 SENP6 UBR5 UBR5 TRIP12 TRIP12 ENSBMUP00000035452 ENSBMUP00000035452 M91_02869 M91_02869 CHEK2 CHEK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M91_03257Small ubiquitin-related modifier. (105 aa)
ENSBMUP00000000180annotation not available (181 aa)
M91_11341Histone H2A; Belongs to the histone H2A family. (145 aa)
UBE2ZUbiquitin-conjugating enzyme E2 Z. (323 aa)
M91_06400Small ubiquitin-related modifier 1. (80 aa)
ENSBMUP00000001831annotation not available (108 aa)
NFATC2IPNuclear factor of activated T-cells 2 interacting protein. (413 aa)
SENP1Sentrin-specific protease 1. (737 aa)
UBE2BUbiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
UBE3CUbiquitin-protein ligase E3C. (1063 aa)
ENSBMUP00000003025annotation not available (96 aa)
M91_12934Ubiquitin-conjugating enzyme E2 D3. (78 aa)
UBE2Q2Ubiquitin-conjugating enzyme E2 Q2. (374 aa)
RNF169RING finger protein 169. (708 aa)
M91_16898UBIQUITIN_CONJUGAT_2 domain-containing protein. (71 aa)
CDC34Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (234 aa)
ENSBMUP00000005059annotation not available (173 aa)
ABRAXAS1BRCA1-A complex subunit Abraxas. (428 aa)
ENSBMUP00000005800annotation not available (173 aa)
SAE1SUMO-activating enzyme subunit 1. (346 aa)
ENSBMUP00000006401annotation not available (91 aa)
ENSBMUP00000007008annotation not available (98 aa)
ENSBMUP00000007365annotation not available (182 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PIAS1E3 SUMO-protein ligase PIAS1. (651 aa)
PIAS3E3 SUMO-protein ligase PIAS3. (628 aa)
ENSBMUP00000008758annotation not available (214 aa)
ZMIZ2Zinc finger MIZ domain-containing protein 2. (922 aa)
ENSBMUP00000009019annotation not available (245 aa)
BRCC3Lys-63-specific deubiquitinase BRCC36. (291 aa)
CNFNCornifelin. (111 aa)
RANBP2E3 SUMO-protein ligase RanBP2. (3033 aa)
MDC1Mediator of DNA damage checkpoint protein 1. (1065 aa)
ENSBMUP00000009984annotation not available (144 aa)
ENSBMUP00000010118annotation not available (187 aa)
UBR1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1615 aa)
KCTD2BTB/POZ domain-containing protein KCTD2. (263 aa)
UBE2UUbiquitin-conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (319 aa)
SUMO2Small ubiquitin-related modifier. (88 aa)
LOC102272795Keratin, type II microfibrillar, component 7C-like. (170 aa)
RNF165RING finger protein 165. (154 aa)
LOC102272480Aquaporin-12B; Belongs to the MIP/aquaporin (TC 1.A.8) family. (307 aa)
UBE2WPutative ubiquitin-conjugating enzyme E2 W. (196 aa)
SENP7Sentrin-specific protease 7. (1044 aa)
UBE2AUbiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
UBE2G1Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
ENSBMUP00000013730annotation not available (61 aa)
ENSBMUP00000013748annotation not available (165 aa)
SENP2Sentrin-specific protease 2. (589 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1289 aa)
UBE2Q1Ubiquitin-conjugating enzyme E2 Q1. (422 aa)
ENSBMUP00000014459Protein PML-like. (66 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
ENSBMUP00000014858annotation not available (108 aa)
TMEM189Transmembrane protein 189. (193 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1. (168 aa)
UBA6Ubiquitin-like modifier-activating enzyme 6. (1057 aa)
RAD18E3 ubiquitin-protein ligase RAD18. (501 aa)
ENSBMUP00000015985annotation not available (210 aa)
ENSBMUP00000016033annotation not available (74 aa)
ENSBMUP00000016303annotation not available (169 aa)
ENSBMUP00000016464annotation not available (106 aa)
PIAS2E3 SUMO-protein ligase PIAS2. (621 aa)
ENSBMUP00000016987annotation not available (53 aa)
BABAM2BRCA1-A complex subunit BRE. (383 aa)
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1756 aa)
ENSBMUP00000018262annotation not available (138 aa)
ENSBMUP00000018439annotation not available (91 aa)
ZNF451Zinc finger protein 451. (1048 aa)
RLIME3 ubiquitin-protein ligase RLIM. (611 aa)
LOC102271309Ubiquitin-conjugating enzyme E2 D3-like. (148 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
MGLLMonoglyceride lipase. (363 aa)
ENSBMUP00000020374annotation not available (159 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa)
UBE2KUbiquitin-conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (212 aa)
RANGAP1Ran GTPase-activating protein 1. (584 aa)
CCDC197Uncharacterized protein. (265 aa)
ENSBMUP00000022134annotation not available (164 aa)
UBE2R2Ubiquitin-conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
SUMO1Small ubiquitin-related modifier. (147 aa)
ENSBMUP00000024181annotation not available (101 aa)
UBCPolyubiquitin-C. (305 aa)
ENSBMUP00000024507annotation not available (137 aa)
UIMC1Uncharacterized protein. (225 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (513 aa)
RIF1Replication timing regulatory factor 1. (2465 aa)
RNF44Ring finger protein 44. (432 aa)
ENSBMUP00000026682annotation not available (93 aa)
UBOX5RING finger protein 37. (537 aa)
TP53BP1Tumor suppressor p53-binding protein 1. (1965 aa)
BABAM1BRISC and BRCA1 A complex member 1. (332 aa)
PLAC8Placenta-specific 8 protein. (116 aa)
UBE2J1Ubiquitin-conjugating enzyme E2 J1. (324 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (573 aa)
SENP5Sentrin-specific protease 5. (754 aa)
ENSBMUP00000029324annotation not available (110 aa)
ENSBMUP00000029638annotation not available (60 aa)
PAXIP1PAX-interacting protein 1. (974 aa)
HLTFHelicase-like transcription factor. (1009 aa)
LONRF2LON peptidase N-terminal domain and ring finger 2. (312 aa)
M91_19001BRCA1-A complex subunit RAP80. (201 aa)
ZNF281Zinc finger protein 281. (643 aa)
UBA2SUMO-activating enzyme subunit 2. (640 aa)
UBE2ISUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
HACE1E3 ubiquitin-protein ligase HACE1. (875 aa)
M91_15717Rad60-SLD domain-containing protein. (54 aa)
UBE2HUbiquitin-conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (303 aa)
ENSBMUP00000032263annotation not available (64 aa)
LOC102269547UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
ENSBMUP00000032580annotation not available (197 aa)
UBE2J2Ubiquitin-conjugating enzyme E2 J2. (259 aa)
C1QTNF12Protein FAM132A. (287 aa)
RNF4E3 ubiquitin ligase RNF4. (186 aa)
DSPPDentin sialophosphoprotein. (1249 aa)
RNF38RING finger protein 38. (514 aa)
ENSBMUP00000034243annotation not available (72 aa)
UBA1Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
SENP6Sentrin-specific protease 6. (1115 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2798 aa)
TRIP12Putative E3 ubiquitin-protein ligase TRIP12. (2034 aa)
ENSBMUP00000035452annotation not available (91 aa)
M91_02869Ubiquitin-conjugating enzyme E2 D2. (53 aa)
CHEK2Checkpoint kinase 2. (441 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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